Evaluation of formocresol, calcium hydroxide, ferric sulfate, and MTA primary molar pulpotomies

Objective: The aim of this study is to evaluate four different pulpotomy medicaments in primary molars. Materials and Methods: A total of 147 primary molars with deep caries were treated with four different pulpotomy medicaments (FC: formocresol, FS: ferric sulfate, CH: calcium hydroxide, and MTA: mineral trioxide aggregate) in this study. The criteria for tooth selection for inclusion were no clinical and radiographic evidence of pulp pathology. During 30 months of follow-up at 6-month intervals, clinical and radiographic success and failures were recorded. The differences between the groups were statistically analyzed using the Chi-square test and Kaplan-Meier analysis. Results: At 30 months, clinical success rates were 100%, 95.2%, 96.4%, and 85% in the FC, FS, MTA, and CH groups, respectively. In radiographic analysis, the MTA group had the highest (96.4%), and the CH group had the lowest success rate (85%). There were no clinical and radiographic differences between materials (P > 0.05). Conclusions: Although there were no differences between materials, only in the CH group did three teeth require extraction due to further clinical symptoms of radiographic failures during the 30-month follow-up period. None of the failed teeth in the other groups required extraction during the 30-month follow-up period.

[1]  A. Glenny,et al.  Pulp treatment for extensive decay in primary teeth. , 2014, The Cochrane database of systematic reviews.

[2]  Sampath Anche,et al.  Dental pulp response to collagen and pulpotec cement as pulpotomy agents in primary dentition: A histological study , 2013, Journal of conservative dentistry : JCD.

[3]  H. Varma,et al.  Calcium phosphate cement as an alternative for formocresol in primary teeth pulpotomies. , 2013, Indian journal of dental research : official publication of Indian Society for Dental Research.

[4]  T. Oliveira,et al.  Clinical, radiographic and histologic analysis of the effects of pulp capping materials used in pulpotomies of human primary teeth , 2013, European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry.

[5]  E. Sepet,et al.  Effects of folk medicinal plant extract Ankaferd Blood stopper® in vital primary molar pulpotomy , 2012, European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry.

[6]  John Wright,et al.  Multi-surface composite vs stainless steel crown restorations after mineral trioxide aggregate pulpotomy: a randomized controlled trial. , 2012, Pediatric dentistry.

[7]  A. Haghdoost,et al.  A comparative study of dental pulp response to several pulpotomy agents. , 2010, International endodontic journal.

[8]  Ş. Sarı,et al.  A Comparison of four pulpotomy techniques in primary molars: a long-term follow-up. , 2008, Journal of endodontics.

[9]  D. Sönmez,et al.  Ca(OH)2 pulpotomy in primary teeth. Part I: internal resorption as a complication following pulpotomy. , 2008, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[10]  T. Oliveira,et al.  The effectiveness of mineral trioxide aggregate, calcium hydroxide and formocresol for pulpotomies in primary teeth. , 2008, International endodontic journal.

[11]  Z. Cehreli,et al.  Clinical performance of Class II adhesive restorations in pulpectomized primary molars: 12-month results. , 2008, Journal of dentistry for children.

[12]  P. Abbott,et al.  Clinical, radiographic and histological analysis of the effects of mineral trioxide aggregate used in direct pulp capping and pulpotomies of primary teeth. , 2006, Australian dental journal.

[13]  V. Zivojinović,et al.  Evaluation of three pulpotomy medicaments in primary teeth. , 2005, European journal of paediatric dentistry.

[14]  N. Alamoudi,et al.  Success of mineral trioxide aggregate in pulpotomized primary molars. , 2005, The Journal of clinical pediatric dentistry.

[15]  P. Planells,et al.  Dentin bridge formation after mineral trioxide aggregate (MTA) pulpotomies in primary teeth. , 2005, American journal of dentistry.

[16]  G. Holan,et al.  Long-term evaluation of pulpotomy in primary molars using mineral trioxide aggregate or formocresol. , 2005, Pediatric dentistry.

[17]  A. Khademi,et al.  SUCCESS RATE OF FORMOCRESOL PULPOTOMY VERSUS MINERAL TRIOXIDE AGGREGATE IN HUMAN PRIMARY MOLAR TOOTH , 2004 .

[18]  C. Bramante,et al.  Histologic evaluation of pulpotomies in dog using two types of mineral trioxide aggregate and regular and white Portland cements as wound dressings. , 2004, Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.

[19]  F. García-Godoy,et al.  Microleakage of restorative techniques for pulpotomized primary molars. , 2004, Journal of dentistry for children.

[20]  D. Avery,et al.  Comparison of mineral trioxide aggregate and formocresol as pulp-capping agents in pulpotomized primary teeth. , 2004, Pediatric dentistry.

[21]  N. Farooq,et al.  Caries control and other variables associated with success of primary molar vital pulp therapy. , 2004, Pediatric dentistry.

[22]  P. Judd,et al.  Long-term outcomes of primary molar ferric sulfate pulpotomy and root canal therapy. , 2003, Pediatric dentistry.

[23]  J. Gutmann,et al.  Histological and scanning electron microscopy assessment of various vital pulp-therapy materials. , 2003, Journal of endodontics.

[24]  D. Odont,et al.  Mineral trioxide aggregate vs. formocresol in pulpotomized primary molars: a preliminary report. , 2001, Pediatric dentistry.

[25]  J. Whitworth,et al.  Primary molar pulp therapy--histological evaluation of failure. , 2008, International journal of paediatric dentistry.

[26]  Q. Al-Jame,et al.  Ferric sulfate as pulpotomy agent in primary teeth: twenty month clinical follow-up. , 2000, The Journal of clinical pediatric dentistry.

[27]  J. Whitworth,et al.  An investigation of the relative efficacy of Buckley's Formocresol and calcium hydroxide in primary molar vital pulp therapy. , 2000 .

[28]  F. García-Godoy,et al.  Fracture strength of adhesively restored pulpotomized primary molars. , 1999, ASDC journal of dentistry for children.

[29]  K. Weerheijm,et al.  Calcium hydroxide pulpotomy with a light-cured cavity-sealing material after two years. , 1997, ASDC journal of dentistry for children.

[30]  M. Torabinejad,et al.  Physical and chemical properties of a new root-end filling material. , 1995, Journal of endodontics.

[31]  D. Ranly.  Pulpotomy therapy in primary teeth: new modalities for old rationales. , 1994, Pediatric dentistry.

[32]  R. Udin,et al.  A clinical study of ferric sulfate as a pulpotomy agent in primary teeth. , 1991, Pediatric dentistry.

[33]  U. Schröder.  Effect of an extra-pulpal blood clot on healing following experimental pulpotomy and capping with calcium hydroxide. , 1973, Odontologisk revy.

[34]  E. Emanuel.  Pulp treatment. , 1968, Chronicle.

[35]  H. Zander.  Reaction of the Pulp to Calcium Hydroxide , 1939 .

[36]  C. A. Sweet.  Procedure for Treatment of Exposed and Pulpless Deciduous Teeth , 1930 .

[37]  J. C. Witt,et al.  Solubility of Calcium Hydroxide , 1928 .