Pulmonary edema as a complication of acute airway obstruction.

Acute fulminating pulmonary edema developed in three patients after acute airway obstruction secondary to tumor, strangulation, and interrupted hanging (one case each). The common etiologic factor was vigorous inspiratory effort against a totally obstructed upper airway. Acute pulmonary edema followed the event in minutes to hours and required ventilatory assistance to maintain oxygenation. All patients eventually responded to fluid restriction, diuretics, and steroids. One case was complicated by aspiration of gastric contents following respiratory failure. To our knowledge, this condition is previously unreported in English literature. We presume that the pathogenesis is related to alveolar and capillary damage, induced by the severe negative pressure generated by attempting to inspire against the closed upper airway.

[1]  A. Bernstein,et al.  Re-expansion pulmonary oedema. , 1975, Thorax.

[2]  F. Grover,et al.  Effect of methylprednisolone sodium succinate on experimental pulmonary contusion. , 1974, The Journal of thoracic and cardiovascular surgery.

[3]  J. Trinkle,et al.  Pulmonary Contusion: Pathogenesis and Effect of Various Resuscitative Measures , 1973 .

[4]  Motsay Gj,et al.  Acute respiratory distress syndrome in adults. Definition, etiology and treatment. , 1973 .

[5]  E D Robin,et al.  Pulmonary edema. 2. , 1973, The New England journal of medicine.

[6]  J. Karliner.  Noncardiogenic Forms of Pulmonary Edema , 1972, Circulation.

[7]  M. Klein.  Asphyxia neonatorum caused by foaming. , 1972, Lancet.

[8]  M. E. Childress,et al.  Unilateral pulmonary edema resulting from treatment of spontaneous pneumothorax. , 2015, The American review of respiratory disease.

[9]  M. el-Guindy,et al.  Delayed asphyxia: a cause of death in interrupted hanging and throttling. , 1971, The Journal of the Egyptian Medical Association.

[10]  B. Goetzman,et al.  Hypoxia and iodoacetic acid and alveolocapillary barrier permeability to albumin. , 1970, The American journal of physiology.

[11]  D. Nicoloff,et al.  Hypoxia and Edema of the Perfused Isolated Canine Lung∗ , 1969, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[12]  M. Ziskind,et al.  Acute pulmonary edema following the treatment of spontaneous pneumothorax with excessive negative intrapleural pressure. , 1965, The American review of respiratory disease.

[13]  Swann He.  THE DEVELOPMENT OF PULMONARY EDEMA DURING THE AGONAL PERIOD OF SUDDEN ASPHYXIAL DEATHS. , 1964 .

[14]  Swann He.  Occurrence of pulmonary edema in sudden asphyxial deaths. , 1960 .

[15]  M. Visscher,et al.  The physiology and pharmacology of lung edema. , 1956, Pharmacological reviews.

[16]  W. O. Fenn,et al.  Mechanics of respiration. , 1951, The American journal of medicine.