Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma

[1]  C. Lengerke,et al.  SOX2 amplification is a common event in squamous cell carcinomas of different organ sites. , 2011, Human pathology.

[2]  M. Meyerson,et al.  SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer , 2011, Modern Pathology.

[3]  E. Brambilla,et al.  SOX2 Is an Oncogene Activated by Recurrent 3q26.3 Amplifications in Human Lung Squamous Cell Carcinomas , 2010, PloS one.

[4]  Paulo P. Amaral,et al.  Complex architecture and regulated expression of the Sox2ot locus during vertebrate development. , 2009, RNA.

[5]  G. Daley,et al.  Live cell imaging distinguishes bona fide human iPS cells from partially reprogrammed cells , 2009, Nature Biotechnology.

[6]  A. Regev,et al.  SOX2 Is an Amplified Lineage Survival Oncogene in Lung and Esophageal Squamous Cell Carcinomas , 2009, Nature Genetics.

[7]  G. Daley,et al.  Hematopoietic Development from Human Induced Pluripotent Stem Cells , 2009, Annals of the New York Academy of Sciences.

[8]  Jing Liang,et al.  The Molecular Mechanism Governing the Oncogenic Potential of SOX2 in Breast Cancer* , 2008, Journal of Biological Chemistry.

[9]  S. Orkin,et al.  An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells (DOI:10.1016/j.cell.2008.02.039) , 2008 .

[10]  C. Gontan,et al.  Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. , 2008, Developmental biology.

[11]  A. Regev,et al.  An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors , 2008, Nature Genetics.

[12]  S. Orkin,et al.  An Extended Transcriptional Network for Pluripotency of Embryonic Stem Cells , 2008, Cell.

[13]  George Q. Daley,et al.  Reprogramming of human somatic cells to pluripotency with defined factors , 2008, Nature.

[14]  Shulan Tian,et al.  Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.

[15]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[16]  T. Graf Faculty Opinions recommendation of Induction of pluripotent stem cells from adult human fibroblasts by defined factors. , 2007 .

[17]  K. Ligon,et al.  Embryonic Stem Cell Transcription Factor Signatures in the Diagnosis of Primary and Metastatic Germ Cell Tumors , 2007, The American journal of surgical pathology.

[18]  C. Perou,et al.  The Triple Negative Paradox: Primary Tumor Chemosensitivity of Breast Cancer Subtypes , 2007, Clinical Cancer Research.

[19]  J. Reis-Filho,et al.  Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer , 2007, Modern Pathology.

[20]  Stuart H. Orkin,et al.  A protein interaction network for pluripotency of embryonic stem cells , 2006, Nature.

[21]  Robert Tibshirani,et al.  Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene‐expression subtypes of breast cancer , 2006, Genes, chromosomes & cancer.

[22]  J. Reis-Filho,et al.  Basal-like breast cancer and the BRCA1 phenotype , 2006, Oncogene.

[23]  M. Wegner,et al.  The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors , 2006, Nucleic acids research.

[24]  A. Ashworth,et al.  Basal-like breast carcinomas: clinical outcome and response to chemotherapy , 2006, Journal of Clinical Pathology.

[25]  X. Chen,et al.  The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells , 2006, Nature Genetics.

[26]  J. Benítez,et al.  Prognostic Significance of Basal-Like Phenotype and Fascin Expression in Node-Negative Invasive Breast Carcinomas , 2006, Clinical Cancer Research.

[27]  Y. Tsutani,et al.  Histopathologic Evaluation of Stepwise Progression of Pancreatic Carcinoma with Immunohistochemical Analysis of Gastric Epithelial Transcription Factor SOX2: Comparison of Expression Patterns between Invasive Components and Cancerous or Nonneoplastic Intraductal Components , 2006, Pancreas.

[28]  Megan F. Cole,et al.  Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells , 2005, Cell.

[29]  Christina Backes,et al.  Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[30]  Peter Devilee,et al.  Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations. , 2005, Cancer research.

[31]  A. Ashworth,et al.  Hallmarks of 'BRCAness' in sporadic cancers , 2004, Nature Reviews Cancer.

[32]  D. Wilhelm,et al.  Sox genes and cancer , 2004, Cytogenetic and Genome Research.

[33]  O. Olopade,et al.  Estrogen Receptor Status in BRCA1- and BRCA2-Related Breast Cancer , 2004, Clinical Cancer Research.

[34]  Y. Eishi,et al.  Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma. , 2004, International journal of oncology.

[35]  P. V. van Diest,et al.  In lymph node‐negative invasive breast carcinomas, specific chromosomal aberrations are strongly associated with high mitotic activity and predict outcome more accurately than grade, tumour diameter, and oestrogen receptor , 2003, The Journal of pathology.

[36]  L. Pevny,et al.  SOX2 Functions to Maintain Neural Progenitor Identity , 2003, Neuron.

[37]  Philip M. Long,et al.  Breast cancer classification and prognosis based on gene expression profiles from a population-based study , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[38]  R. Tibshirani,et al.  Repeated observation of breast tumor subtypes in independent gene expression data sets , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[39]  Marcel J T Reinders,et al.  Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors. , 2002, Cancer research.

[40]  P. Koopman,et al.  Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. , 2002, Current opinion in genetics & development.

[41]  R. Tibshirani,et al.  Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[42]  B. Wullich,et al.  Novel amplification unit at chromosome 3q25–q27 in human prostate cancer , 2000, The Prostate.

[43]  Christian A. Rees,et al.  Molecular portraits of human breast tumours , 2000, Nature.

[44]  D. Jäger,et al.  Serological identification of embryonic neural proteins as highly immunogenic tumor antigens in small cell lung cancer. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[45]  H. Kondoh,et al.  Pairing SOX off: with partners in the regulation of embryonic development. , 2000, Trends in genetics : TIG.

[46]  Lin Yang,et al.  Transcriptional regulatory networks in embryonic stem cells. , 2011, Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques.

[47]  R. Lovell-Badge,et al.  Multipotent cell lineages in early mouse development depend on SOX2 function. , 2003, Genes & development.