Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.
暂无分享,去创建一个
S. Gygi | I. Harris | J. Brugge | J. L. Coloff | L. Selfors | J. Murphy | Laura M. Shelton | Kenjiro Kami | J. P. Murphy | C. Braun | K. Kami | Jonathan L. Coloff
[1] Christian M. Metallo,et al. Branched chain amino acid catabolism fuels adipocyte differentiation and lipogenesis , 2015, Nature chemical biology.
[2] R. Deberardinis,et al. NRF2 regulates serine biosynthesis in non-small cell lung cancer , 2015, Nature Genetics.
[3] A. Vazquez,et al. Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis , 2015, Nature Cell Biology.
[4] M. V. Heiden,et al. Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells , 2015, Cell.
[5] D. Sabatini,et al. An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis , 2015, Cell.
[6] S. Gygi,et al. Comprehensive Temporal Protein Dynamics during the Diauxic Shift in Saccharomyces cerevisiae , 2015, Molecular & Cellular Proteomics.
[7] Liangfeng Han,et al. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate , 2015, Clinical Cancer Research.
[8] Robert A. Egnatchik,et al. Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. , 2015, Cancer cell.
[9] R. Deberardinis,et al. Glutamine oxidation maintains the TCA cycle and cell survival during impaired mitochondrial pyruvate transport. , 2014, Molecular cell.
[10] J. Blenis,et al. The mTORC1/S6K1 Pathway Regulates Glutamine Metabolism through the eIF4B-Dependent Control of c-Myc Translation , 2014, Current Biology.
[11] Michael L. Gatza,et al. An integrated genomics approach identifies drivers of proliferation in luminal subtype human breast cancer , 2014, Nature Genetics.
[12] S. Gygi,et al. Combining Amine Metabolomics and Quantitative Proteomics of Cancer Cells Using Derivatization with Isobaric Tags , 2014, Analytical chemistry.
[13] John Quackenbush,et al. Gene Expression Signature of Normal Cell-of-Origin Predicts Ovarian Tumor Outcomes , 2013, PloS one.
[14] Ralph J DeBerardinis,et al. Glutamine and cancer: cell biology, physiology, and clinical opportunities. , 2013, The Journal of clinical investigation.
[15] K. Vosseller,et al. O-GlcNAc in cancer biology , 2013, Amino Acids.
[16] B. Manning,et al. Signal integration by mTORC1 coordinates nutrient input with biosynthetic output , 2013, Nature Cell Biology.
[17] Gregory Stephanopoulos,et al. The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4 , 2013, Cell.
[18] R. Kaufman,et al. ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death , 2013, Nature Cell Biology.
[19] Ronan M. T. Fleming,et al. A community-driven global reconstruction of human metabolism , 2013, Nature Biotechnology.
[20] John M. Asara,et al. Glutamine supports pancreatic cancer growth through a Kras-regulated metabolic pathway , 2013, Nature.
[21] G. Stephanopoulos,et al. Loss of RBF1 changes glutamine catabolism. , 2013, Genes & development.
[22] J. Maris,et al. ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation. , 2012, Cancer cell.
[23] A. McClatchey,et al. Contact inhibition (of proliferation) redux. , 2012, Current opinion in cell biology.
[24] H. Aburatani,et al. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic reprogramming. , 2012, Cancer cell.
[25] G. Mills,et al. Akt and ERK Control the Proliferative Response of Mammary Epithelial Cells to the Growth Factors IGF-1 and EGF Through the Cell Cycle Inhibitor p57Kip2 , 2012, Science Signaling.
[26] J. Brugge,et al. Outgrowth of Single Oncogene-expressing Cells from Suppressive Epithelial Environments , 2012, Nature.
[27] H. Coller. The Essence of Quiescence , 2011, Science.
[28] M. V. Vander Heiden,et al. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. , 2011, Annual review of cell and developmental biology.
[29] David Venet,et al. Most Random Gene Expression Signatures Are Significantly Associated with Breast Cancer Outcome , 2011, PLoS Comput. Biol..
[30] Gregory Stephanopoulos,et al. Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis , 2012, BMC Proceedings.
[31] C. Stanley,et al. The structure and allosteric regulation of glutamate dehydrogenase , 2011, Neurochemistry International.
[32] Taotao Lao,et al. Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells , 2010, Cell cycle.
[33] Elizabeth L. Johnson,et al. Quiescent Fibroblasts Exhibit High Metabolic Activity , 2010, PLoS biology.
[34] Mark T. W. Ebbert,et al. A Comparison of PAM50 Intrinsic Subtyping with Immunohistochemistry and Clinical Prognostic Factors in Tamoxifen-Treated Estrogen Receptor–Positive Breast Cancer , 2010, Clinical Cancer Research.
[35] Gregory Stephanopoulos,et al. Nontargeted elucidation of metabolic pathways using stable-isotope tracers and mass spectrometry. , 2010, Analytical chemistry.
[36] R. Deberardinis,et al. Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. , 2009, Cancer research.
[37] Hanna Y. Irie,et al. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment , 2009, Nature.
[38] L. Cantley,et al. Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation , 2009, Science.
[39] F. Middleton,et al. Activation of Mammalian Target of Rapamycin Controls the Loss of TCRζ in Lupus T Cells through HRES-1/Rab4-Regulated Lysosomal Degradation1 , 2009, The Journal of Immunology.
[40] Anthony Mancuso,et al. Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction , 2008, Proceedings of the National Academy of Sciences.
[41] A. Lane,et al. Targeting aspartate aminotransferase in breast cancer , 2008, Breast Cancer Research.
[42] J. Rathmell,et al. Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival , 2008, Journal of leukocyte biology.
[43] Mina J Bissell,et al. Unraveling the microenvironmental influences on the normal mammary gland and breast cancer. , 2008, Seminars in cancer biology.
[44] R. Deberardinis,et al. Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis , 2007, Proceedings of the National Academy of Sciences.
[45] Kenneth M. Yamada,et al. Modeling Tissue Morphogenesis and Cancer in 3D , 2007, Cell.
[46] C. Adams. Role of the Transcription Factor ATF4 in the Anabolic Actions of Insulin and the Anti-anabolic Actions of Glucocorticoids* , 2007, Journal of Biological Chemistry.
[47] Zena Werb,et al. GATA-3 Maintains the Differentiation of the Luminal Cell Fate in the Mammary Gland , 2006, Cell.
[48] F. Alt,et al. SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells , 2006, Cell.
[49] Jayanta Debnath,et al. Modelling glandular epithelial cancers in three-dimensional cultures , 2005, Nature Reviews Cancer.
[50] Kara Dolinski,et al. Homeostatic adjustment and metabolic remodeling in glucose-limited yeast cultures. , 2005, Molecular biology of the cell.
[51] J. Blenis,et al. mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E , 2004, Molecular and Cellular Biology.
[52] P. Hammerman,et al. Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival , 2003, Molecular and Cellular Biology.
[53] C. Thompson,et al. The CD28 signaling pathway regulates glucose metabolism. , 2002, Immunity.
[54] N. Robakis,et al. Novel human glutamate dehydrogenase expressed in neural and testicular tissues and encoded by an X-linked intronless gene. , 1994, The Journal of biological chemistry.
[55] A. Zetterberg,et al. Glutamine and the regulation of DNA replication and cell multiplication in fibroblasts , 1981, Journal of cellular physiology.
[56] D. E. Atkinson. The energy charge of the adenylate pool as a regulatory parameter. Interaction with feedback modifiers. , 1968, Biochemistry.
[57] 이연수. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer , 2011 .
[58] Tsung-Cheng Chang,et al. c-Myc suppression of miR-23 enhances mitochondrial glutaminase and glutamine metabolism , 2009, Nature.
[59] J. Mitchison. Cell Biology , 1964, Nature.