Cellular FLICE-inhibitory protein (c-FLIP) signalling: a key regulator of receptor-mediated apoptosis in physiologic context and in cancer.
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[1] S. Canevari,et al. c-FLIPL expression defines two ovarian cancer patient subsets and is a prognostic factor of adverse outcome. , 2009, Endocrine-related cancer.
[2] A. Safa,et al. RNA interference in cancer: targeting the anti-apoptotic protein c-FLIP for drug discovery. , 2009, Mini reviews in medicinal chemistry.
[3] Yigong Shi,et al. Mechanism of procaspase-8 activation by c-FLIPL , 2009, Proceedings of the National Academy of Sciences.
[4] H. Walczak,et al. Is TRAIL the holy grail of cancer therapy? , 2009, Apoptosis.
[5] G. Tiegs,et al. Down-regulation of the De-ubiquitinating Enzyme Ubiquitin-specific Protease 2 Contributes to Tumor Necrosis Factor-α-induced Hepatocyte Survival* , 2009, Journal of Biological Chemistry.
[6] G. Melino,et al. p63 regulates the caspase-8-FLIP apoptotic pathway in epidermis , 2008, Cell Death and Differentiation.
[7] B. Tsang,et al. Cisplatin induces p53-dependent FLICE-like inhibitory protein ubiquitination in ovarian cancer cells. , 2008, Cancer research.
[8] H. Gollnick,et al. Suppression of cFLIP is sufficient to sensitize human melanoma cells to TRAIL- and CD95L-mediated apoptosis , 2008, Oncogene.
[9] V. Bumbasirevic,et al. TRAIL induces proliferation of human glioma cells by c-FLIPL-mediated activation of ERK1/2 , 2008, Cellular and Molecular Life Sciences.
[10] A. Safa,et al. Cellular FLICE-like inhibitory protein (C-FLIP): a novel target for cancer therapy. , 2008, Current cancer drug targets.
[11] K. Okumura,et al. Downregulation of c-FLIP promotes caspase-dependent JNK activation and reactive oxygen species accumulation in tumor cells , 2008, Oncogene.
[12] F. Khuri,et al. Lipid rafts and nonrafts mediate tumor necrosis factor related apoptosis-inducing ligand induced apoptotic and nonapoptotic signals in non small cell lung carcinoma cells. , 2007, Cancer research.
[13] Daniel B Longley,et al. c-FLIP: a key regulator of colorectal cancer cell death. , 2007, Cancer research.
[14] Wendy L. Allen,et al. Cellular FLICE-inhibitory protein regulates chemotherapy-induced apoptosis in breast cancer cells , 2007, Molecular Cancer Therapeutics.
[15] Xiaoping Zhang,et al. MG-132 Sensitizes TRAIL-Resistant Prostate Cancer Cells by Activating c-Fos/c-Jun Heterodimers and Repressing c-FLIP(L) , 2007 .
[16] S. Canevari,et al. Sensitization of p53-mutated epithelial ovarian cancer to CD95-mediated apoptosis is synergistically induced by cisplatin pretreatment , 2007, Molecular Cancer Therapeutics.
[17] W. Yeh,et al. An antiapoptotic protein, c‐FLIPL, directly binds to MKK7 and inhibits the JNK pathway , 2006, The EMBO journal.
[18] P. Krammer,et al. The c-FLIP–NH2 terminus (p22-FLIP) induces NF-κB activation , 2006, The Journal of experimental medicine.
[19] M. Karin,et al. The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover , 2006, Cell.
[20] W L Allen,et al. c-FLIP inhibits chemotherapy-induced colorectal cancer cell death , 2006, Oncogene.
[21] J. Tschopp,et al. Life and death decisions: secondary complexes and lipid rafts in TNF receptor family signal transduction. , 2004, Immunity.
[22] S. Canevari,et al. CD95-Mediated Apoptosis Is Impaired at Receptor Level by Cellular FLICE-Inhibitory Protein (Long Form) in Wild-Type p53 Human Ovarian Carcinoma , 2004, Clinical Cancer Research.
[23] J. Tschopp,et al. N-Terminal Fragment of c-FLIP(L) Processed by Caspase 8 Specifically Interacts with TRAF2 and Induces Activation of the NF-κB Signaling Pathway , 2004, Molecular and Cellular Biology.
[24] B. Tsang,et al. Resistance of Human Ovarian Cancer Cells to Tumor Necrosis Factor α Is a Consequence of Nuclear Factor κB-Mediated Induction of Fas-Associated Death Domain-Like Interleukin-1β-Converting Enzyme-Like Inhibitory Protein , 2003 .
[25] Scott W. Lowe,et al. Apoptosis A Link between Cancer Genetics and Chemotherapy , 2002, Cell.
[26] D. Goeddel,et al. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. , 2000, Immunity.
[27] Ingo Schmitz,et al. The Role of c-FLIP in Modulation of CD95-induced Apoptosis* , 1999, The Journal of Biological Chemistry.
[28] Margot Thome,et al. Inhibition of death receptor signals by cellular FLIP , 1997, Nature.
[29] P. Vandenabeele,et al. Caspases in cell survival, proliferation and differentiation , 2007, Cell Death and Differentiation.