Pre-travel vaccine information needs, attitudes, drivers of uptake and the role for decision aids in travel medicine

Abstract Background Many travellers do not receive vaccines pre-travel. Tools such as vaccine decision aids could support informed vaccine decision-making. We aimed to characterise Australians’ pre-travel vaccine attitudes, behaviours and information needs and examine the role for decision aids in travel medicine. Methods Online cross-sectional survey of Australian adults in December 2022. We included questions on demographics, pre-travel health-seeking behaviour, and information needs. We measured vaccine confidence (Vaccine Confidence Index Index) and used hypothetical disease scenarios to evaluate behavioural and social drivers of vaccination. We used multivariable logistic regression models to identify predictors of vaccine uptake and thematically analysed free-text responses. Results We received complete survey responses from 1223/1326 Australians (92% response rate). Amongst those reporting previous overseas travel, 67% (778/1161) reported past pre-travel health encounter(s) and 64% (743/1161) reported past pre-travel vaccination. Half (50%) strongly agreed that vaccines were important for their health; fewer strongly agreed that vaccines were safe (37%) and effective (38%). In multivariable analyses, past pre-travel vaccine uptake was associated with increasing age (OR = 1.17 [95% CI 1.08–1.27] p < 0.001 per ten-year increase) and travel to higher-risk destinations (OR = 2.92 [2.17–3.93] p < 0.001); travellers visiting friends and relatives (VFRs) were less likely to have received pre-travel vaccines (OR = 0.74 [0.56–0.97] p = 0.028). Predictors for wanting vaccination against hypothetical diseases included past pre-travel vaccination (Disease X: OR 2.60 [1.91–3.56] p < 0.001) and confidence in vaccine safety (Disease X: OR 7.18 [5.07–10.18], p < 0.001); past VFR travel was predictive of not wanting vaccination (Disease X: OR 0.72 [0.52–1.00], p = 0.049). Most (63%) were interested in using a vaccine decision aid, generally together with a trusted health professional. Conclusions Health professionals play an important role in supporting pre-travel vaccine decision-making. However, our findings indicate that reliable, accurate and engaging digital resources, such as decision aids, could support travellers to make informed pre-travel vaccine decisions.

[1]  P. Leggat,et al.  Types and outcomes of pharmacist-managed travel health services: A systematic review. , 2022, Travel medicine and infectious disease.

[2]  A. Siani,et al.  Is vaccine confidence an unexpected victim of the COVID-19 pandemic? , 2022, Vaccine.

[3]  W. Ricciardi,et al.  Social media and attitudes towards a COVID-19 vaccination: A systematic review of the literature , 2022, eClinicalMedicine.

[4]  Mahmudul Hassan Al Imam,et al.  "Scary to get, more scary not to": COVID-19 vaccine acceptance among healthcare workers in Central Queensland, Australia, a cross-sectional survey. , 2022, Communicable diseases intelligence.

[5]  Kirby Goidel,et al.  Imperfect messengers? An analysis of vaccine confidence among primary care physicians , 2022, Vaccine.

[6]  S. Lehmann,et al.  Characterizing polarization in online vaccine discourse—A large-scale study , 2022, PloS one.

[7]  C. Molony,et al.  Using social media listening and data mining to understand travellers’ perspectives on travel disease risks and vaccine-related attitudes and behaviours , 2022, Journal of travel medicine.

[8]  K. Lavoie,et al.  Attitudes towards vaccines and intention to vaccinate against COVID-19: a cross-sectional analysis—implications for public health communications in Australia , 2022, BMJ Open.

[9]  G. Elwyn,et al.  Shared decision‐making interventions: An overview and a meta‐analysis of their impact on vaccine uptake , 2021, Journal of internal medicine.

[10]  K. Leder,et al.  Typhoid fever in travellers: estimating the risk of acquisition by country , 2021, Journal of travel medicine.

[11]  C. Masuet-Aumatell,et al.  Acceptance of yellow fever vaccine in the older traveller: a cohort study , 2021, Acta bio-medica : Atenei Parmensis.

[12]  A. Chughtai,et al.  Trust in government, intention to vaccinate and COVID-19 vaccine hesitancy: A comparative survey of five large cities in the United States, United Kingdom, and Australia , 2021, Vaccine.

[13]  J. Leask,et al.  A systematic review and meta-analysis of effectiveness of decision aids for vaccination decision-making. , 2021, Vaccine.

[14]  S. Lewandowsky,et al.  Effects of different types of written vaccination information on COVID-19 vaccine hesitancy in the UK (OCEANS-III): a single-blind, parallel-group, randomised controlled trial , 2021, The Lancet Public Health.

[15]  M. Hiligsmann,et al.  Vaccine preferences driving vaccine-decision making of different target groups: a systematic review of choice-based experiments , 2020, BMC Infectious Diseases.

[16]  H. Larson,et al.  Mapping global trends in vaccine confidence and investigating barriers to vaccine uptake: a large-scale retrospective temporal modelling study , 2020, The Lancet.

[17]  S. Omer,et al.  Efficacy of a Web-Based Intervention to Increase Uptake of Maternal Vaccines: An RCT. , 2019, American journal of preventive medicine.

[18]  O. Brady,et al.  Factors Affecting Pre-Travel Health Seeking Behaviour and Adherence to Pre-Travel Health Advice: A Systematic Review. , 2019, Journal of travel medicine.

[19]  Paul A. Harris,et al.  The REDCap consortium: Building an international community of software platform partners , 2019, J. Biomed. Informatics.

[20]  Sowmya R. Rao,et al.  Characteristics and preparation of the last-minute traveler: analysis of vaccine usage in the Global TravEpiNet Consortium , 2019, Journal of travel medicine.

[21]  K. Khan,et al.  How Can We Keep Immigrant Travelers Healthy? Health Challenges Experienced by Canadian South Asian Travelers Visiting Friends and Relatives , 2018, Qualitative health research.

[22]  C. Poulos,et al.  German travelers' preferences for travel vaccines assessed by a discrete choice experiment. , 2018, Vaccine.

[23]  Iain G. Johnston,et al.  The State of Vaccine Confidence 2016: Global Insights Through a 67-Country Survey , 2016, EBioMedicine.

[24]  C. Macintyre,et al.  The contribution of travellers visiting friends and relatives to notified infectious diseases in Australia: state-based enhanced surveillance , 2016, Epidemiology and Infection.

[25]  C. Macintyre,et al.  Improving the uptake of pre-travel health advice amongst migrant Australians: exploring the attitudes of primary care providers and migrant community groups , 2016, BMC Infectious Diseases.

[26]  N. MacDonald Vaccine hesitancy: Definition, scope and determinants. , 2015, Vaccine.

[27]  K. Leder,et al.  Immediate recall of health issues discussed during a pre-travel consultation. , 2015, Journal of travel medicine.

[28]  Sowmya R. Rao,et al.  Pre-Travel Health Preparation of Pediatric International Travelers: Analysis From the Global TravEpiNet Consortium. , 2013, Journal of the Pediatric Infectious Diseases Society.

[29]  K. Leder,et al.  Aggregate travel vs. single trip assessment: arguments for cumulative risk analysis. , 2012, Vaccine.

[30]  N. Gallagher,et al.  Pretravel health preparation among US residents traveling to India to VFRs: importance of ethnicity in defining VFRs. , 2009, Journal of travel medicine.

[31]  S. Pocock,et al.  The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. , 2007, Preventive medicine.

[32]  V. Braun,et al.  Using thematic analysis in psychology , 2006 .

[33]  Marco Magenta,et al.  Legislation , 1980, Archives des Maladies Professionnelles et de l'Environnement.

[34]  N. Zwar,et al.  Improving access and provision of pre-travel healthcare for travellers visiting friends and relatives: a review of the evidence. , 2018, Journal of travel medicine.

[35]  THE ACT GOVERNMENT , 2018 .

[36]  P. V. van Genderen,et al.  Import and spread of extended-spectrum β-lactamase-producing Enterobacteriaceae by international travellers (COMBAT study): a prospective, multicentre cohort study. , 2017, The Lancet. Infectious diseases.

[37]  sennis About the sample size calculator , 2017 .