Leptin levels predict the development of insulin resistance in a sample of adult men-The Olivetti Heart Study.

[1]  Pasquale Strazzullo,et al.  Circulating leptin levels predict the decline in renal function with age in a sample of adult men (The Olivetti Heart Study) , 2019, Internal and Emergency Medicine.

[2]  M. Banach,et al.  Leptin, cardiovascular diseases and type 2 diabetes mellitus , 2018, Acta Pharmacologica Sinica.

[3]  V. Somers,et al.  Statins decrease leptin expression in human white adipocytes , 2018, Physiological reports.

[4]  J. Holst,et al.  Effect of liraglutide on ectopic fat in polycystic ovary syndrome: A randomized clinical trial , 2018, Diabetes, obesity & metabolism.

[5]  S. Li,et al.  The effect of sitagliptin on obese patients with insulin treatment-induced diabetes mellitus. , 2017, European review for medical and pharmacological sciences.

[6]  A. Sahebkar,et al.  Effect of ezetimibe on plasma adipokines: a systematic review and meta‐analysis , 2017, British journal of clinical pharmacology.

[7]  Z. Yao,et al.  Liraglutide ameliorates palmitate-induced endothelial dysfunction through activating AMPK and reversing leptin resistance. , 2016, Biochemical and biophysical research communications.

[8]  J. Correale,et al.  Immunologic Effects of Metformin and Pioglitazone Treatment on Metabolic Syndrome and Multiple Sclerosis. , 2016, JAMA neurology.

[9]  A. Sahebkar,et al.  Improvement of plasma adiponectin, leptin and C-reactive protein concentrations by orlistat: a systematic review and meta-analysis. , 2016, British journal of clinical pharmacology.

[10]  M. Hanafi,et al.  Modulation of Adipocytokines Production and Serum NEFA Level by Metformin, Glimepiride, and Sitagliptin in HFD/STZ Diabetic Rats , 2015, Biochemistry research international.

[11]  D. Morgan,et al.  Leptin Receptor Signaling in the Hypothalamus Regulates Hepatic Autonomic Nerve Activity via Phosphatidylinositol 3-Kinase and AMP-Activated Protein Kinase , 2015, The Journal of Neuroscience.

[12]  R. Grempler,et al.  Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet , 2014, Diabetes, metabolic syndrome and obesity : targets and therapy.

[13]  R. Bloigu,et al.  Long-term fructose feeding changes the expression of leptin receptors and autophagy genes in the adipose tissue and liver of male rats: a possible link to elevated triglycerides , 2013, Genes & Nutrition.

[14]  K. Labuzek,et al.  Effects of 90-day hypolipidemic treatment on insulin resistance, adipokines and proinflammatory cytokines in patients with mixed hyperlipidemia and impaired fasting glucose. , 2012, International journal of clinical pharmacology and therapeutics.

[15]  M. Quon,et al.  Deterioration of glucose homeostasis in type 2 diabetic patients one year after beginning of statins therapy. , 2012, Atherosclerosis.

[16]  F. Cappuccio,et al.  Hyperleptinemia is associated with hypertension, systemic inflammation and insulin resistance in overweight but not in normal weight men. , 2012, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[17]  G. Frühbeck,et al.  Leptin Reduces the Expression and Increases the Phosphorylation of the Negative Regulators of GLUT4 Traffic TBC1D1 and TBC1D4 in Muscle of ob/ob Mice , 2012, PloS one.

[18]  Yan-ming Sun,et al.  Effect of statin therapy on leptin levels in patients with coronary heart disease , 2010, Peptides.

[19]  D. Pupek-Musialik,et al.  Leptin, soluble leptin receptors, free leptin index, and their relationship with insulin resistance and BMI: high normal BMI is the threshold for serum leptin increase in humans. , 2010, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[20]  M. Myers,et al.  Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis , 2010, Diabetes.

[21]  F. Kim,et al.  Hypothalamic leptin signaling regulates hepatic insulin sensitivity via a neurocircuit involving the vagus nerve. , 2009, Endocrinology.

[22]  A. Siani,et al.  High-circulating leptin levels are associated with greater risk of hypertension in men independently of body mass and insulin resistance: results of an eight-year follow-up study. , 2008, The Journal of clinical endocrinology and metabolism.

[23]  U. Broedl,et al.  Adipokines and Insulin Resistance , 2008, Molecular medicine.

[24]  F. Cappuccio,et al.  Circulating leptin levels predict the development of metabolic syndrome in middle-aged men: an 8-year follow-up study , 2007, Journal of hypertension.

[25]  J. Flier,et al.  Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells. , 2006, Cell metabolism.

[26]  W. Haynes Role of leptin in obesity‐related hypertension , 2005, Experimental physiology.

[27]  U. Ekelund,et al.  Leptin predicts a worsening of the features of the metabolic syndrome independently of obesity. , 2005, Obesity research.

[28]  H. Münzberg,et al.  Molecular and anatomical determinants of central leptin resistance , 2005, Nature Neuroscience.

[29]  A. Yoshimura,et al.  Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity , 2004, Nature Medicine.

[30]  P. Strazzullo,et al.  Plasma leptin measurements in epidemiological investigation: comparison of two commonly used assays and estimate of regression dilution bias. , 2002, Nutrition, metabolism, and cardiovascular diseases : NMCD.

[31]  K. Clément,et al.  Soluble leptin receptor in serum of subjects with complete resistance to leptin: relation to fat mass. , 2000, Diabetes.

[32]  N. Chinookoswong,et al.  Leptin restores euglycemia and normalizes glucose turnover in insulin-deficient diabetes in the rat. , 1999, Diabetes.

[33]  S. Kiechl,et al.  Prevalence of insulin resistance in metabolic disorders: the Bruneck Study. , 1998, Diabetes.

[34]  D. Morgan,et al.  Effects of leptin on insulin sensitivity in normal rats. , 1997, Endocrinology.

[35]  G W Becker,et al.  Leptin is a four‐helix bundle: secondary structure by NMR , 1997, FEBS letters.

[36]  R. Considine,et al.  Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance , 1996, The Lancet.

[37]  R. Considine,et al.  Serum immunoreactive-leptin concentrations in normal-weight and obese humans. , 1996, The New England journal of medicine.

[38]  J. Habener,et al.  Signal transduction crosstalk in the endocrine system: pancreatic beta-cells and the glucose competence concept. , 1992, Trends in biochemical sciences.

[39]  P. Kirchhof,et al.  The task force for the management ofarterial hypertension of the european society ofhypertension (esh) and of the european society of cardiology (esc) , 2013 .

[40]  R. Curi,et al.  Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation , 1999, International Journal of Obesity.