A common single-nucleotide variant in T is strongly associated with chordoma

[1]  Paul Flicek,et al.  An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma , 2012, The Journal of pathology.

[2]  Julie M. Batten,et al.  Recurrent Chromosomal Copy Number Alterations in Sporadic Chordomas , 2011, PloS one.

[3]  P. Bosco,et al.  APOE and Alzheimer disease: a major gene with semi-dominant inheritance , 2011, Molecular Psychiatry.

[4]  Raymond K. Auerbach,et al.  A User's Guide to the Encyclopedia of DNA Elements (ENCODE) , 2011, PLoS biology.

[5]  T. Jacques,et al.  Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional‐based study , 2011, The Journal of pathology.

[6]  N. Carter,et al.  Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development , 2011, Cell.

[7]  David I. Smith,et al.  Tumor Transcriptome Sequencing Reveals Allelic Expression Imbalances Associated with Copy Number Alterations , 2010, PloS one.

[8]  A. Goldstein,et al.  T (brachyury) gene duplication confers major susceptibility to familial chordoma , 2009, Nature Genetics.

[9]  R. Eeles,et al.  Genome-wide association studies in cancer. , 2008, Human molecular genetics.

[10]  M. D. den Bakker,et al.  Brachyury Expression in Extra-axial Skeletal and Soft Tissue Chordomas: A Marker that Distinguishes Chordoma From Mixed Tumor/Myoepithelioma/Parachordoma in Soft Tissue , 2008, The American journal of surgical pathology.

[11]  S. Henderson,et al.  Brachyury, a crucial regulator of notochordal development, is a novel biomarker for chordomas , 2006, The Journal of pathology.

[12]  Derek L. Stemple,et al.  Structure and function of the notochord: an essential organ for chordate development , 2005, Development.

[13]  A. Goldstein,et al.  Chordoma: incidence and survival patterns in the United States, 1973–1995 , 2004, Cancer Causes & Control.

[14]  C B Begg,et al.  The lifetime risks of breast cancer in Ashkenazi Jewish carriers of BRCA1 and BRCA2 mutations. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[15]  J. Sowden,et al.  The T transcription factor functions as a dimer and exhibits a common human polymorphism Gly‐177‐Asp in the conserved DNA‐binding domain , 1997, FEBS letters.