From Acute Pancreatitis to Pancreonekrosis during Pregnancy

Acute pancreatitis during pregnancy, although a rare but extremely formidable complication, is accompanied by a high level of perinatal and maternal mortality. Excessive hypertriglyceridemia is an extremely important risk factor for pancreatitis, especially during pregnancy. The secretion of cholesterol in hepatic bile increases in the second and reaches a peak in the third trimester compared with bile acids and phospholipids, which leads to a supersaturation of bile. Which determines the highest incidence of acute pancreatitis in pregnant women in the third trimester. The acute onset, the nature of the disease and the difficulties in diagnosis in the treatment of acute pancreatitis in pregnant women significantly threaten the health of the mother and fetus. Although most authors argue that treating acute pancreatitis during pregnancy is similar to treating non-pregnant patients, this is actually far from the truth. During pregnancy, the features of the pathogenesis of acute pancreatitis in pregnant women come to the fore, which must be taken into account when managing these patients.