Towards the mechanism of spermatotoxicity of p-tert-butyl-alpha-methylhydrocinnamic aldehyde: inhibition of late stage ex-vivo spermatogenesis in rat seminiferous tubule cultures by para-tert-butyl- benzoic acid

[1]  D. Sévin,et al.  Exometabolome profiling reveals activation of the carnitine buffering pathway in fed‐batch cultures of CHO cells co‐fed with glucose and lactic acid , 2021, Biotechnology progress.

[2]  A. Natsch,et al.  Benzoyl-CoA conjugate accumulation as an initiating event for male reprotoxic effects in the rat? Structure–activity analysis, species specificity, and in vivo relevance , 2020, Archives of Toxicology.

[3]  Guo-Fang Zhang,et al.  Propionate-induced changes in cardiac metabolism, notably CoA trapping, are not altered by l-carnitine. , 2018, American journal of physiology. Endocrinology and metabolism.

[4]  A. Natsch,et al.  p-Alkyl-Benzoyl-CoA Conjugates as Relevant Metabolites of Aromatic Aldehydes With Rat Testicular Toxicity—Studies Leading to the Design of a Safer New Fragrance Chemical , 2017, Toxicological sciences : an official journal of the Society of Toxicology.

[5]  Thomas Hartung,et al.  Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells , 2017, Archives of Toxicology.

[6]  Takao Shimizu,et al.  Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis , 2017, The Journal of Biological Chemistry.

[7]  H. Koch,et al.  Human metabolism and excretion kinetics of the fragrance lysmeral after a single oral dosage. , 2017, International journal of hygiene and environmental health.

[8]  K. Goldstein,et al.  Use of a rat ex-vivo testis culture method to assess toxicity of select known male reproductive toxicants. , 2016, Reproductive toxicology.

[9]  M. Darnell,et al.  Metabolism of xenobiotic carboxylic acids: focus on coenzyme A conjugation, reactivity, and interference with lipid metabolism. , 2013, Chemical research in toxicology.

[10]  M. Capecchi,et al.  ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice , 2011, Journal of Lipid Research.

[11]  T. Ehrhardt,et al.  The Herbicide Saflufenacil (Kixor™) is a New Inhibitor of Protoporphyrinogen IX Oxidase Activity , 2010, Weed Science.

[12]  Manabu T. Nakamura,et al.  Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration , 2009, Journal of Lipid Research.

[13]  S. Bruner,et al.  Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC. , 2007, Biochemistry.

[14]  M. Godet,et al.  The effects of FSH and of testosterone on the completion of meiosis and the very early steps of spermiogenesis of the rat: an in vitro study. , 2004, Journal of molecular endocrinology.

[15]  R. Ramsay,et al.  Carnitine acyltransferases and their influence on CoA pools in health and disease. , 2004, Molecular aspects of medicine.

[16]  B B Rudkin,et al.  Developmental changes in cyclin B1 and cyclin-dependent kinase 1 (CDK1) levels in the different populations of spermatogenic cells of the post-natal rat testis. , 2000, European journal of cell biology.

[17]  R. Brownsey,et al.  Bimodal Activation of Acetyl-CoA Carboxylase by Glutamate* , 2000, The Journal of Biological Chemistry.

[18]  E. Brass.  Overview of coenzyme A metabolism and its role in cellular toxicity. , 1994, Chemico-biological interactions.

[19]  R. Harris,et al.  Inhibition of hepatic gluconeogenesis and lipogenesis by benzoic acid, p-tert.-butylbenzoic acid, and a structurally related hypolipidemic agent SC-33459. , 1982, Archives of biochemistry and biophysics.

[20]  V. Caso,et al.  Carnitine protects mitochondria and removes toxic acyls from xenobiotics. , 2001, Drugs under experimental and clinical research.

[21]  M. G..  Human Metabolism , 2022, Nature.