A system biology approach to identify regulatory pathways underlying the neuroendocrine control of female puberty in rats and nonhuman primates
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[1] S. Ojeda,et al. Epigenetic regulation of female puberty , 2015, Frontiers in Neuroendocrinology.
[2] S. Ojeda,et al. Epigenetic Control of Female Puberty , 2013, Nature Neuroscience.
[3] J. Mackay,et al. Two-timing zinc finger transcription factors liaising with RNA. , 2012, Trends in biochemical sciences.
[4] S. Ojeda,et al. Transcription of the human EAP1 gene is regulated by upstream components of a puberty-controlling Tumor Suppressor Gene network , 2012, Molecular and Cellular Endocrinology.
[5] Joshua Kim,et al. Assessment of epigenetic contributions to sexually-dimorphic Kiss1 expression in the anteroventral periventricular nucleus of mice. , 2012, Endocrinology.
[6] Joshua Kim,et al. Development, sex steroid regulation, and phenotypic characterization of RFamide-related peptide (Rfrp) gene expression and RFamide receptors in the mouse hypothalamus. , 2012, Endocrinology.
[7] A. Topaloğlu,et al. Inactivating KISS1 mutation and hypogonadotropic hypogonadism. , 2012, The New England journal of medicine.
[8] R. Harris,et al. Gene Coexpression Networks in Human Brain Identify Epigenetic Modifications in Alcohol Dependence , 2012, The Journal of Neuroscience.
[9] C. Caligioni,et al. Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men. , 2012, Endocrinology.
[10] A. Kauffman,et al. The Role of Kisspeptin and RFamide‐Related Peptide‐3 Neurones in the Circadian‐Timed Preovulatory Luteinising Hormone Surge , 2012, Journal of neuroendocrinology.
[11] S. Opal,et al. Proprotein convertases in health and disease. , 2011, The New England journal of medicine.
[12] Michael Mitzenmacher,et al. Detecting Novel Associations in Large Data Sets , 2011, Science.
[13] S. McWeeney,et al. Occupancy Classification of Position Weight Matrix-Inferred Transcription Factor Binding Sites , 2011, PloS one.
[14] R. Palmiter,et al. Regulation of NKB pathways and their roles in the control of Kiss1 neurons in the arcuate nucleus of the male mouse. , 2011, Endocrinology.
[15] S. Ojeda,et al. Prostaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation , 2011, Proceedings of the National Academy of Sciences.
[16] S. Ojeda,et al. Transcriptional regulation of the human KiSS1 gene , 2011, Molecular and Cellular Endocrinology.
[17] U. Boehm,et al. Female reproductive maturation in the absence of kisspeptin/GPR54 signaling , 2011, Nature Neuroscience.
[18] S. Ojeda,et al. SynCAM1, a synaptic adhesion molecule, is expressed in astrocytes and contributes to erbB4 receptor-mediated control of female sexual development. , 2011, Endocrinology.
[19] S. Ojeda,et al. The synaptic cell adhesion molecule, SynCAM1, mediates astrocyte-to-astrocyte and astrocyte-to-GnRH neuron adhesiveness in the mouse hypothalamus. , 2011, Endocrinology.
[20] S. Ojeda,et al. A Novel Transcription Complex That Selectively Modulates Apoptosis of Breast Cancer Cells through Regulation of FASTKD2 , 2011, Molecular and Cellular Biology.
[21] Derek Y. Chiang,et al. Suppression of Lung Adenocarcinoma Progression by Nkx2-1 , 2011, Nature.
[22] Henriette O'Geen,et al. ZNF274 Recruits the Histone Methyltransferase SETDB1 to the 3′ Ends of ZNF Genes , 2010, PloS one.
[23] S. Ojeda,et al. Contribution of glial–neuronal interactions to the neuroendocrine control of female puberty , 2010, The European journal of neuroscience.
[24] Christian Gieger,et al. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies , 2010, Nature Genetics.
[25] R. Paro,et al. Interpretation of developmental signaling at chromatin: the Polycomb perspective. , 2010, Developmental cell.
[26] J. R. Kurian,et al. Epigenetic changes coincide with in vitro primate GnRH neuronal maturation. , 2010, Endocrinology.
[27] Shannon McWeeney,et al. Genetic diversity and striatal gene networks: focus on the heterogeneous stock-collaborative cross (HS-CC) mouse , 2010, BMC Genomics.
[28] C. Dubay,et al. Gene networks and the neuroendocrine regulation of puberty , 2010, Molecular and Cellular Endocrinology.
[29] W. Colledge,et al. The role of kisspeptin signaling in reproduction. , 2010, Physiology.
[30] L. Kriegsfeld,et al. Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function , 2010, Frontiers in Neuroendocrinology.
[31] Gary D. Bader,et al. The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function , 2010, Nucleic Acids Res..
[32] K. Mogi,et al. Neurokinin B and Dynorphin A in Kisspeptin Neurons of the Arcuate Nucleus Participate in Generation of Periodic Oscillation of Neural Activity Driving Pulsatile Gonadotropin-Releasing Hormone Secretion in the Goat , 2010, The Journal of Neuroscience.
[33] Wei Keat Lim,et al. The transcriptional network for mesenchymal transformation of brain tumors , 2009, Nature.
[34] Giacomo Cavalli,et al. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling , 2009, Nature Genetics.
[35] R. Steiner,et al. Kisspeptin signaling in the brain. , 2009, Endocrine reviews.
[36] Robert E. Kingston,et al. Mechanisms of Polycomb gene silencing: knowns and unknowns , 2009, Nature Reviews Molecular Cell Biology.
[37] Donald K. Clifton,et al. Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse , 2009, The Journal of Neuroscience.
[38] K. Harvey,et al. A tumor suppressive activity of Drosophila Polycomb genes mediated by JAK/STAT signaling , 2009, Nature Genetics.
[39] S. Balasubramanian,et al. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans , 2009, Nature Structural &Molecular Biology.
[40] R. Gregory,et al. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in embryonic stem cells , 2009, Nature Structural &Molecular Biology.
[41] C. Joo,et al. TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation , 2009, Cell.
[42] W. Colledge,et al. Distribution of Kisspeptin Neurones in the Adult Female Mouse Brain , 2009, Journal of neuroendocrinology.
[43] D. Koh,et al. A Novel POK Family Transcription Factor, ZBTB5, Represses Transcription of p21CIP1 Gene* , 2009, The Journal of Biological Chemistry.
[44] A. Herbison,et al. RFamide-related peptide-3, a mammalian gonadotropin-inhibitory hormone ortholog, regulates gonadotropin-releasing hormone neuron firing in the mouse. , 2009, Endocrinology.
[45] E. Demerath,et al. Meta-analysis of genome-wide association data identifies two loci influencing age at menarche , 2009, Nature Genetics.
[46] D. Gudbjartsson,et al. Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche , 2009, Nature Genetics.
[47] P. Ridker,et al. Genome-wide association studies identify novel loci associated with age at menarche and age at natural menopause , 2009, Nature Genetics.
[48] Madeleine P. Ball,et al. Targeted and genome-scale methylomics reveals gene body signatures in human cell lines , 2009, Nature Biotechnology.
[49] Michael A. Beer,et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation , 2009, Proceedings of the National Academy of Sciences.
[50] Frank Reimann,et al. TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction , 2009, Nature Genetics.
[51] O. Rønnekleiv,et al. FXYD1, a Modulator of Na+,K+‐ATPase Activity, Facilitates Female Sexual Development by Maintaining Gonadotrophin‐Releasing Hormone Neuronal Excitability , 2009, Journal of neuroendocrinology.
[52] J. Baik,et al. Kinesin superfamily-associated protein 3 is preferentially expressed in glutamatergic neurons and contributes to the excitatory control of female puberty. , 2008, Endocrinology.
[53] D. Reich,et al. Association studies of common variants in 10 hypogonadotropic hypogonadism genes with age at menarche. , 2008, The Journal of clinical endocrinology and metabolism.
[54] L. Kriegsfeld,et al. Alterations in RFamide-related peptide expression are coordinated with the preovulatory luteinizing hormone surge. , 2008, Endocrinology.
[55] C. Ha,et al. NELL2, a Neuron-Specific EGF-Like Protein, Is Selectively Expressed in Glutamatergic Neurons and Contributes to the Glutamatergic Control of GnRH Neurons at Puberty , 2008, Neuroendocrinology.
[56] S. Ojeda,et al. Glial–Gonadotrophin Hormone (GnRH) Neurone Interactions in the Median Eminence and the Control of GnRH Secretion , 2008, Journal of neuroendocrinology.
[57] C. Villar,et al. Programming of gene expression by Polycomb group proteins. , 2008, Trends in cell biology.
[58] F. Ebling,et al. RFAmide-related peptide: another sexy peptide? , 2008, Endocrinology.
[59] Bin Zhang,et al. Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R , 2008, Bioinform..
[60] S. Ojeda,et al. Gene Expression Profiling of Hypothalamic Hamartomas: A Search for Genes Associated with Central Precocious Puberty , 2007, Hormone Research in Paediatrics.
[61] E. Peles,et al. A Contactin–Receptor‐Like Protein Tyrosine Phosphatase β Complex Mediates Adhesive Communication Between Astroglial Cells and Gonadotrophin‐Releasing Hormone Neurones , 2007, Journal of neuroendocrinology.
[62] C. Dubay,et al. Expression of a tumor-related gene network increases in the mammalian hypothalamus at the time of female puberty. , 2007, Endocrinology.
[63] R. Steiner,et al. Emerging ideas about kisspeptin– GPR54 signaling in the neuroendocrine regulation of reproduction , 2007, Trends in Neurosciences.
[64] Felecia Cerrato,et al. Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice. , 2007, Endocrinology.
[65] G. Bédécarrats,et al. Mutations in the human gonadotropin-releasing hormone receptor: insights into receptor biology and function. , 2007, Seminars in reproductive medicine.
[66] T. Mikkelsen,et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells , 2007, Nature.
[67] S. Ojeda,et al. Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis. , 2007, The Journal of clinical investigation.
[68] R. Jaenisch,et al. A Chromatin Landmark and Transcription Initiation at Most Promoters in Human Cells , 2007, Cell.
[69] Shane C. Dillon,et al. The landscape of histone modifications across 1% of the human genome in five human cell lines. , 2007, Genome research.
[70] Michael B. Stadler,et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome , 2007, Nature Genetics.
[71] J. Costoya. Functional analysis of the role of POK transcriptional repressors. , 2007, Briefings in functional genomics & proteomics.
[72] Robert Gentleman,et al. Using GOstats to test gene lists for GO term association , 2007, Bioinform..
[73] S. Ojeda,et al. Deletion of the Ttf1 Gene in Differentiated Neurons Disrupts Female Reproduction without Impairing Basal Ganglia Function , 2006, The Journal of Neuroscience.
[74] Ben Abbas,et al. Human heterochromatin proteins form large domains containing KRAB-ZNF genes. , 2006, Genome research.
[75] Michael K. Skinner,et al. CHAPTER 38 – Puberty in the Rat , 2006 .
[76] J. Daniel,et al. POZ for effect--POZ-ZF transcription factors in cancer and development. , 2006, Trends in cell biology.
[77] M. Tena-Sempere. KiSS-1 and Reproduction: Focus on Its Role in the Metabolic Regulation of Fertility , 2006, Neuroendocrinology.
[78] S. Ojeda,et al. Quantitative proteomics identifies a change in glial glutamate metabolism at the time of female puberty , 2006, Molecular and Cellular Endocrinology.
[79] R. Steiner,et al. Kiss1 Neurons in the Forebrain as Central Processors for Generating the Preovulatory Luteinizing Hormone Surge , 2006, The Journal of Neuroscience.
[80] S. Hinuma,et al. Recent advances in mammalian RFamide peptides: The discovery and functional analyses of PrRP, RFRPs and QRFP , 2006, Peptides.
[81] S. Ojeda,et al. Minireview: the neuroendocrine regulation of puberty: is the time ripe for a systems biology approach? , 2006, Endocrinology.
[82] D. Brann,et al. Role of astrocytes in reproduction and neuroprotection , 2006, Molecular and Cellular Endocrinology.
[83] B. Dudas,et al. Three‐Dimensional Representation of the Neurotransmitter Systems of the Human Hypothalamus: Inputs of the Gonadotrophin Hormone‐Releasing Hormone Neuronal System , 2006, Journal of neuroendocrinology.
[84] M. Costa,et al. Hypothalamic Tumor Necrosis Factor-α Converting Enzyme Mediates Excitatory Amino Acid-Dependent Neuron-to-Glia Signaling in the Neuroendocrine Brain , 2006, The Journal of Neuroscience.
[85] Guillaume J. Filion,et al. A Family of Human Zinc Finger Proteins That Bind Methylated DNA and Repress Transcription , 2006, Molecular and Cellular Biology.
[86] K. S. Deshpande,et al. Human protein reference database—2006 update , 2005, Nucleic Acids Res..
[87] Suzanne M. Moenter,et al. Endogenous γ-Aminobutyric Acid Can Excite Gonadotropin-Releasing Hormone Neurons , 2005 .
[88] G. Kaur,et al. Neuronal-glial plasticity in gonadotropin-releasing hormone release in adult female rats: role of the polysialylated form of the neural cell adhesion molecule. , 2005, The Journal of endocrinology.
[89] W. Lam,et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells , 2005, Nature Genetics.
[90] William J. R. Longabaugh,et al. Computational representation of developmental genetic regulatory networks. , 2005, Developmental biology.
[91] R. Natarajan,et al. Mapping Global Histone Methylation Patterns in the Coding Regions of Human Genes , 2005, Molecular and Cellular Biology.
[92] Adam A. Margolin,et al. Reverse engineering of regulatory networks in human B cells , 2005, Nature Genetics.
[93] S. Ojeda,et al. Increased hypothalamic GPR54 signaling: a potential mechanism for initiation of puberty in primates. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[94] Masamitsu Iino,et al. System-level identification of transcriptional circuits underlying mammalian circadian clocks , 2005, Nature Genetics.
[95] A. Erkanli,et al. Genetic and environmental influences on the relative timing of pubertal change. , 2004, Twin research : the official journal of the International Society for Twin Studies.
[96] Annie E. Hill,et al. Chromosomes 6 and 13 harbor genes that regulate pubertal timing in mouse chromosome substitution strains. , 2004, Endocrinology.
[97] M. Gerstein,et al. Genomic analysis of regulatory network dynamics reveals large topological changes , 2004, Nature.
[98] John D. Storey. The positive false discovery rate: a Bayesian interpretation and the q-value , 2003 .
[99] A Finney,et al. Systems biology markup language: Level 2 and beyond. , 2003, Biochemical Society transactions.
[100] P. Shannon,et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. , 2003, Genome research.
[101] S. O’Rahilly,et al. The GPR54 Gene as a Regulator of Puberty , 2003 .
[102] Hanno Steen,et al. Development of human protein reference database as an initial platform for approaching systems biology in humans. , 2003, Genome research.
[103] Y. Kitamura,et al. IGSF4: a new intercellular adhesion molecule that is called by three names, TSLC1, SgIGSF and SynCAM, by virtue of its diverse function. , 2003, Histology and histopathology.
[104] Raul Urrutia,et al. KRAB-containing zinc-finger repressor proteins , 2003, Genome Biology.
[105] E. Génin,et al. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[106] P. Steeg,et al. Metastasis suppressor genes: basic biology and potential clinical use. , 2003, Clinical breast cancer.
[107] Suzanne M. Moenter,et al. Activation of A-type gamma-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons. , 2002, Molecular endocrinology.
[108] A. Barabasi,et al. Hierarchical Organization of Modularity in Metabolic Networks , 2002, Science.
[109] S. Khochbin,et al. Class II Histone Deacetylases Are Directly Recruited by BCL6 Transcriptional Repressor* , 2002, The Journal of Biological Chemistry.
[110] L. Hood,et al. A Genomic Regulatory Network for Development , 2002, Science.
[111] V. Prévot. Glial–Neuronal–Endothelial Interactions are Involved in the Control of GnRH Secretion , 2002, Journal of neuroendocrinology.
[112] S. Schiffmann,et al. The Metastasis Suppressor Gene KiSS-1 Encodes Kisspeptins, the Natural Ligands of the Orphan G Protein-coupled Receptor GPR54* , 2001, The Journal of Biological Chemistry.
[113] W. Crowley,et al. Perspective: the importance of genetic defects in humans in elucidating the complexities of the hypothalamic-pituitary-gonadal axis. , 2001, Endocrinology.
[114] Roger E Bumgarner,et al. Integrated genomic and proteomic analyses of a systematically perturbed metabolic network. , 2001, Science.
[115] H. Fukuhara,et al. TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer , 2001, Nature Genetics.
[116] E. Terasawa,et al. Neurobiological mechanisms of the onset of puberty in primates. , 2001, Endocrine reviews.
[117] M. Costa,et al. TTF-1, a Homeodomain Gene Required for Diencephalic Morphogenesis, Is Postnatally Expressed in the Neuroendocrine Brain in a Developmentally Regulated and Cell-Specific Fashion , 2001, Molecular and Cellular Neuroscience.
[118] A Nava,et al. Characterization of C14orf4, a novel intronless human gene containing a polyglutamine repeat, mapped to the ARVD1 critical region. , 2000, Biochemical and biophysical research communications.
[119] Masaki Tanaka,et al. New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals , 2000, Nature Cell Biology.
[120] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[121] M. Costa,et al. The Oct-2 POU domain gene in the neuroendocrine brain: a transcriptional regulator of mammalian puberty. , 1999, Endocrinology.
[122] E Branscomb,et al. Comparative analysis of a conserved zinc finger gene cluster on human chromosome 19q and mouse chromosome 7. , 1996, Genomics.
[123] C. Lagenaur,et al. Postnatal expression of polysialic acid-neural cell adhesion molecule in the hypothalamus of the male rhesus monkey (Macaca mulatta). , 1993, Endocrinology.
[124] S. Ojeda,et al. The juvenile-peripubertal transition period in the female rat: establishment of a diurnal pattern of pulsatile luteinizing hormone secretion. , 1985, Endocrinology.
[125] H. Imura,et al. Suppressive effect of dynorphin-(1-13) on luteinizing hormone release in conscious castrated rats. , 1982, Life sciences.
[126] K. Pirke,et al. β-Endorphin and dynorphin control serum luteinizing hormone level in immature female rats , 1981, Nature.
[127] S. Ojeda,et al. A single-nucleotide polymorphism in the EAP1 gene is associated with amenorrhea/oligomenorrhea in nonhuman primates. , 2012, Endocrinology.
[128] S. Ojeda,et al. Hypothalamic EAP1 (enhanced at puberty 1) is required for menstrual cyclicity in nonhuman primates. , 2012, Endocrinology.
[129] S. Lightman,et al. The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat. , 2012, Endocrinology.
[130] M. Kemal Sönmez,et al. Computing graphlet signatures of network nodes and motifs in Cytoscape with GraphletCounter , 2012, Bioinform..
[131] S. Horvath,et al. A General Framework for Weighted Gene Co-Expression Network Analysis , 2005, Statistical applications in genetics and molecular biology.
[132] Michael N Lehman,et al. Kisspeptin / Neurokinin B / Dynorphin ( KNDy ) Cells of the Arcuate Nucleus : A Central Node in the Control of Gonadotropin-Releasing Hormone Secretion , 2010 .
[133] S. Ojeda,et al. A Role for Glial Cells of the Neuroendocrine Brain in the Central Control of Female Sexual Development , 2009 .
[134] Vincenzo Pirrotta,et al. Polycomb silencing mechanisms and the management of genomic programmes , 2007, Nature Reviews Genetics.
[135] T. Plant,et al. CHAPTER 40 – Puberty in Nonhuman Primates* and Humans , 2006 .
[136] Hiroaki Kitano,et al. Next generation simulation tools: the Systems Biology Workbench and BioSPICE integration. , 2003, Omics : a journal of integrative biology.
[137] S. Ojeda,et al. Neuroendocrine Regulation of Puberty , 2000 .
[138] Xianrang Song,et al. Maturation of a central , 1996 .
[139] W. McGuire,et al. Breast Cancer 4 , 1981, Springer US.
[140] Thomas Lengauer,et al. Bioinformatics Original Paper Improved Scoring of Functional Groups from Gene Expression Data by Decorrelating Go Graph Structure , 2022 .
[141] J. T. Smith,et al. A Role for Kisspeptins in the Regulation of Gonadotropin Secretion in the Mouse Materials and Methods Animals and Chemicals , 2022 .
[142] P. Deloukas,et al. Serveur Académique Lausannois SERVAL serval.unil.ch , 2022 .