NFATc1 Promotes Prostate Tumorigenesis and Overcomes PTEN Loss-Induced Senescence
暂无分享,去创建一个
Matthew H Bailey | L. Ding | P. Humphrey | C. Maher | G. Andriole | F. Chen | Hong Zhang | Jie Ning | H. Liapis | P. Tripathi | Z. You | Matthew H. Bailey | A. Hsi | M. Ruzinova | K. Manda | J. Ning
[1] Yi Li,et al. The role of NFATc1 in prostate cancer progression: Cyclosporine A and tacrolimus inhibit cell proliferation, migration, and invasion , 2015, The Prostate.
[2] Zhongming Zhao,et al. Key regulators in prostate cancer identified by co-expression module analysis , 2014, BMC Genomics.
[3] Z. Culig. Proinflammatory cytokine interleukin-6 in prostate carcinogenesis. , 2014, American journal of clinical and experimental urology.
[4] C. Creighton,et al. VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2 , 2014, Oncogene.
[5] A. Tewari,et al. Inflammation and prostate cancer: the role of interleukin 6 (IL‐6) , 2014, BJU international.
[6] A. Carnero,et al. The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models , 2014, Front. Oncol..
[7] E. Antonarakis,et al. Castration-resistant prostate cancer: latest evidence and therapeutic implications , 2014, Therapeutic advances in medical oncology.
[8] J. Pfeifer,et al. Activation of NFAT signaling establishes a tumorigenic microenvironment through cell autonomous and non-cell autonomous mechanisms , 2014, Oncogene.
[9] R. Agarwal,et al. Silibinin inhibits prostate cancer cells‐ and RANKL‐induced osteoclastogenesis by targeting NFATc1, NF‐κB, and AP‐1 activation in RAW264.7 cells , 2014, Molecular carcinogenesis.
[10] S. Komarova,et al. Molecular Signaling Pathways Mediating Osteoclastogenesis Induced by Prostate Cancer Cells , 2013, BMC Cancer.
[11] M. Moore,et al. Genomic Rearrangements of PTEN in Prostate Cancer , 2013, Front. Oncol..
[12] M. Pan,et al. NFAT gene family in inflammation and cancer. , 2013, Current molecular medicine.
[13] Lianfeng Zhang,et al. STAT3 interacts with Skp2/p27/p21 pathway to regulate the motility and invasion of gastric cancer cells. , 2013, Cellular signalling.
[14] M. Serrano,et al. PTEN in cancer, metabolism, and aging , 2013, Trends in Endocrinology & Metabolism.
[15] Daniel J. Devine,et al. Cytoplasmic translocation of p21 mediates NUPR1‐induced chemoresistance , 2012, FEBS letters.
[16] Wenrong Zhao,et al. Stat3 induces oncogenic Skp2 expression in human cervical carcinoma cells. , 2012, Biochemical and biophysical research communications.
[17] L. Trusolino,et al. Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils , 2011, EMBO molecular medicine.
[18] A. Toker,et al. NFAT promotes carcinoma invasive migration through glypican-6 , 2011, The Biochemical journal.
[19] Frank McCormick,et al. Cancer therapy based on oncogene addiction , 2011, Journal of surgical oncology.
[20] Gerald C. Chu,et al. SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression , 2011, Nature.
[21] Feng Chen,et al. Activation of NFAT signaling in podocytes causes glomerulosclerosis. , 2010, Journal of the American Society of Nephrology : JASN.
[22] Vassiliki Tzelepi,et al. Therapeutic targeting of the prostate cancer microenvironment , 2010, Nature Reviews Urology.
[23] C. Sander,et al. Integrative genomic profiling of human prostate cancer. , 2010, Cancer cell.
[24] E. Agardh,et al. Nuclear Factor of Activated T‐cells (NFAT) regulates osteopontin expression in arterial smooth muscle in response to diabetes‐induced hyperglycemia , 2010 .
[25] A. Kozubík,et al. Breast cancer-specific mutations in CK1ε inhibit Wnt/β-catenin and activate the Wnt/Rac1/JNK and NFAT pathways to decrease cell adhesion and promote cell migration , 2010, Breast Cancer Research.
[26] Manoj Bhasin,et al. Identification of the Transcription Factor Single-Minded Homologue 2 as a Potential Biomarker and Immunotherapy Target in Prostate Cancer , 2009, Clinical Cancer Research.
[27] L. Lagunas,et al. Deregulated NFATc1 activity transforms murine fibroblasts via an autocrine growth factor‐mediated Stat3‐dependent pathway , 2009, Journal of cellular biochemistry.
[28] J. Viola,et al. Dual Roles for NFAT Transcription Factor Genes as Oncogenes and Tumor Suppressors , 2008, Molecular and Cellular Biology.
[29] Yahui Kong,et al. Suppression of human tumor cell proliferation by Smurf2‐induced senescence , 2008, Journal of cellular physiology.
[30] C. Alberti. Genetic and microenvironmental implications in prostate cancer progression and metastasis. , 2008, European review for medical and pharmacological sciences.
[31] A. Joe,et al. Oncogene addiction. , 2008, Cancer research.
[32] N. Prevarskaya,et al. TRPV6 channel controls prostate cancer cell proliferation via Ca2+/NFAT-dependent pathways , 2007, Oncogene.
[33] G. Crabtree,et al. Enhanced NFATc1 Nuclear Occupancy Causes T Cell Activation Independent of CD28 Costimulation1 , 2007, The Journal of Immunology.
[34] T. Gress,et al. Overexpression of c‐myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway , 2006, The EMBO journal.
[35] A. Toker,et al. NFAT Induces Breast Cancer Cell Invasion by Promoting the Induction of Cyclooxygenase-2* , 2006, Journal of Biological Chemistry.
[36] A. Toker,et al. Akt blocks breast cancer cell motility and invasion through the transcription factor NFAT. , 2005, Molecular cell.
[37] J. Whitsett,et al. Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction , 2005, Nucleic acids research.
[38] C. Kao,et al. NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen. , 2003, Journal of molecular biology.
[39] J. Neal,et al. A Constitutively Active NFATc1 Mutant Induces a Transformed Phenotype in 3T3-L1 Fibroblasts* , 2003, The Journal of Biological Chemistry.
[40] M. Blagosklonny. Are p27 and p21 Cytoplasmic Oncoproteins? , 2002, Cell cycle.
[41] Leslie M. Shaw,et al. The role of NFAT transcription factors in integrin-mediated carcinoma invasion , 2002, Nature Cell Biology.
[42] I. Graef,et al. NFAT signaling in vertebrate development. , 2001, Current opinion in genetics & development.
[43] T. Yeatman,et al. Stat3-mediated Myc expression is required for Src transformation and PDGF-induced mitogenesis , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[44] P. Roy-Burman,et al. Generation of a prostate epithelial cell-specific Cre transgenic mouse model for tissue-specific gene ablation , 2001, Mechanisms of Development.
[45] T. Hirano,et al. Stat3 Is Required for the Gp130-mediated Full Activation of the C-myc Gene , 1999 .
[46] P. Briand,et al. The effect of estrone-progesterone treatment on cell proliferation kinetics of hormone-dependent GR mouse mammary tumors. , 1975, Cancer research.