Renal tubular dysfunction in children with sickle cell haemoglobinopathy

Children with sickle cell disease (SCD) are remarkably more prone than others to renal dysfunction. The kidneys, as one of the systemic long‐term hazards in SCD, may be affected by both the haemodynamic changes of chronic anaemia as well as by the consequences of vaso‐occlusion. The aim of this study was to evaluate the proximal tubular function in a group of Saudi children with established SCD.

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