Disambiguation of Multiple Sequence Learning by Theta Phase Coding

In spatial alternation tasks, the same place in different behavioral sequences is represented by different neurons in the rat hippocampus. This indicates that associative memory in the brain solves the memory interference problem at each instance. By assuming that different behavioral sequences are encoded in different continuous attractors, we hypothesize that theta rhythm-dependent activity provides cooperation between external input and retrieval of the behavioral episode. In our computer experiments, these two activities with an appropriate phase difference enable the maintaining of a consistent attractor in accordance with behavior. It suggests neural dynamics for the real-time process of associate memory.

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