Free radicals and brain aging.
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[1] L. Horrocks,et al. Acidic hydrolysis of plasmalogens followed by high-performance liquid chromatography , 1993, Lipids.
[2] D. Butterfield,et al. Quantitative proteomics analysis of specific protein expression and oxidative modification in aged senescence-accelerated-prone 8 mice brain , 2004, Neuroscience.
[3] Giovanni Scapagnini,et al. Free radicals: key to brain aging and heme oxygenase as a cellular response to oxidative stress. , 2004, The journals of gerontology. Series A, Biological sciences and medical sciences.
[4] D. Butterfield. Proteomics: a new approach to investigate oxidative stress in Alzheimer's disease brain , 2004, Brain Research.
[5] Stefani N. Thomas,et al. High-Throughput Proteomic-Based Identification of Oxidatively Induced Protein Carbonylation in Mouse Brain , 2003, Pharmaceutical Research.
[6] D. Butterfield,et al. Disruption of Thiol Homeostasis and Nitrosative Stress in the Cerebrospinal Fluid of Patients with Active Multiple Sclerosis: Evidence for a Protective Role of Acetylcarnitine , 2003, Neurochemical Research.
[7] D. Bechtold,et al. Induction of Hsp27 and Hsp32 Stress Proteins and Vimentin in Glial Cells of the Rat Hippocampus Following Hyperthermia , 2003, Neurochemical Research.
[8] S. Pasquaré,et al. Age-Associated Changes in Central Nervous System Glycerolipid Composition and Metabolism , 2002, Neurochemical Research.
[9] V. Calabrese,et al. Mitochondrial Involvement in Brain Function and Dysfunction: Relevance to Aging, Neurodegenerative Disorders and Longevity , 2001, Neurochemical Research.
[10] V. Calabrese,et al. NO Synthase and NO-Dependent Signal Pathways in Brain Aging and Neurodegenerative Disorders: The Role of Oxidant/Antioxidant Balance , 2000, Neurochemical Research.
[11] D. Butterfield,et al. The Free Radical Antioxidant Vitamin E Protects Cortical Synaptosomal Membranes from Amyloid β-Peptide(25-35) Toxicity But Not from Hydroxynonenal Toxicity: Relevance to the Free Radical Hypothesis of Alzheimer's Disease , 1998, Neurochemical Research.
[12] L. Balázs,et al. Evidence of an oxidative challenge in the Alzheimer's brain , 1994, Neurochemical Research.
[13] J. Vitorica,et al. Age-related quantitative changes in enzyme activities of rat brain , 1981, Neurochemical Research.
[14] G. Kaur,et al. Mitochondrial electron transport chain complexes in aging rat brain and lymphocytes , 2004, Biogerontology.
[15] G. Kaur,et al. Alterations in oxidative stress scavenger system in aging rat brain and lymphocytes , 2004, Biogerontology.
[16] The proteomics of ageing , 2004, Biogerontology.
[17] H. Schipper,et al. Role of heme oxygenase-1 in the biogenesis of corpora amylacea , 2004, Biogerontology.
[18] D. Butterfield,et al. Elevation of mitochondrial glutathione by γ‐glutamylcysteine ethyl ester protects mitochondria against peroxynitrite‐induced oxidative stress , 2003, Journal of neuroscience research.
[19] Robert F Service. Public Projects Gear Up to Chart the Protein Landscape , 2003, Science.
[20] D. Butterfield,et al. Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: A nutritional approach , 2003, Amino Acids.
[21] N. Kaplowitz,et al. Sensitivity of the 2‐oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion , 2003, Hepatology.
[22] R. Mikkelsen,et al. Biological chemistry of reactive oxygen and nitrogen and radiation-induced signal transduction mechanisms , 2003, Oncogene.
[23] D. Butterfield,et al. Proteomics in Alzheimer's disease: insights into potential mechanisms of neurodegeneration , 2003, Journal of neurochemistry.
[24] Federico V Pallardó,et al. The role of mitochondrial oxidative stress in aging. , 2003, Free radical biology & medicine.
[25] J. Morrow,et al. Age-independent, gray matter-localized, brain-enhanced oxidative stress in male fischer 344 rats: brain levels of F(2)-isoprostanes and F(4)-neuroprostanes. , 2003, Free radical biology & medicine.
[26] J. Ji,et al. Proteomic comparison between human young and old brains by two-dimensional gel electrophoresis and identification of proteins , 2003, International Journal of Developmental Neuroscience.
[27] R. Rodnight,et al. Changes in heat shock protein 27 phosphorylation and immunocontent in response to preconditioning to oxygen and glucose deprivation in organotypic hippocampal cultures , 2003, Neuroscience.
[28] Rui Wang,et al. Interaction of Selective Amino Acid Residues of KCa Channels with Carbon Monoxide , 2003, Experimental biology and medicine.
[29] C. Schöneich. Proteomics in gerontological research , 2003, Experimental Gerontology.
[30] J. Hirrlinger,et al. Glutathione Pathways in the Brain , 2003, Biological chemistry.
[31] S. Nigam,et al. Aging, lipid modifications and phospholipases—new concepts , 2003, Ageing Research Reviews.
[32] B. Ames. Review Article: Delaying the Mitochondrial Decay of Aging—a Metabolic Tune‐up , 2003, Alzheimer disease and associated disorders.
[33] Mayer Rj. From neurodegeneration to neurohomeostasis: the role of ubiquitin. , 2003 .
[34] D. Butterfield,et al. The antioxidants α‐lipoic acid and N‐acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice , 2003, Journal of neurochemistry.
[35] P. Parsons,et al. Influence of ageing, heat shock treatment and in vivo total antioxidant status on gene-expression profile and protein synthesis in human peripheral lymphocytes , 2003, Mechanisms of Ageing and Development.
[36] H. Remmen,et al. Comparative proteomics: characterization of a two-dimensional gel electrophoresis system to study the effect of aging on mitochondrial proteins , 2003, Mechanisms of Ageing and Development.
[37] R. Mayer. From neurodegeneration to neurohomeostasis: the role of ubiquitin. , 2003, Drug news & perspectives.
[38] W. Dröge. Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants , 2002, Experimental Gerontology.
[39] B. Ames,et al. Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[40] M. Kim,et al. Immunohistochemical study on the distribution of nitrotyrosine and neuronal nitric oxide synthase in aged rat cerebellum , 2002, Brain Research.
[41] K. Hensley,et al. Oxidative stress in brain aging Implications for therapeutics of neurodegenerative diseases , 2002, Neurobiology of Aging.
[42] R. S. Sohal,et al. Mechanisms of aging: an appraisal of the oxidative stress hypothesis. , 2002, Free radical biology & medicine.
[43] D. Butterfield,et al. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II: dihydropyrimidinase‐related protein 2, α‐enolase and heat shock cognate 71 , 2002, Journal of neurochemistry.
[44] B. Öztaş,et al. Comparison of the Activities of Na+,K+-ATPase in Brains of Rats at Different Ages , 2002, Gerontology.
[45] D. Butterfield,et al. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. , 2002, Free radical biology & medicine.
[46] D. Butterfield,et al. Nutritional approaches to combat oxidative stress in Alzheimer's disease. , 2002, The Journal of nutritional biochemistry.
[47] R. Sapolsky,et al. Gene transfer of HSP72 protects cornu ammonis 1 region of the hippocampus neurons from global ischemia: Influence of Bcl‐2 , 2002, Annals of neurology.
[48] B. Ames,et al. Oxidative damage increases with age in a canine model of human brain aging , 2002, Journal of neurochemistry.
[49] D. Butterfield,et al. Molecular Chaperones and Their Roles in Neural Cell Differentiation , 2002, Developmental Neuroscience.
[50] D. Butterfield,et al. Elevated glutathione as a therapeutic strategy in Alzheimer's disease , 2002 .
[51] D. Butterfield,et al. Elevation of brain glutathione by γ‐glutamylcysteine ethyl ester protects against peroxynitrite‐induced oxidative stress , 2002, Journal of neuroscience research.
[52] G. Sobue,et al. Lipid peroxidation and advanced glycation end products in the brain in normal aging and in Alzheimer's disease , 2002, Acta Neuropathologica.
[53] D. Butterfield,et al. Lipid peroxidation and protein oxidation in Alzheimer's disease brain: Potential causes and consequences involving amyloid β-peptide-associated free radical oxidative stress , 2002 .
[54] T. Montine,et al. Effects of reactive γ‐ketoaldehydes formed by the isoprostane pathway (isoketals) and cyclooxygenase pathway (levuglandins) on proteasome function , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[55] Olivier Toussaint,et al. Proteomics in experimental gerontology , 2002, Experimental Gerontology.
[56] N. Abraham,et al. Regional distribution of heme oxygenase, HSP70, and glutathione in brain: Relevance for endogenous oxidant/antioxidant balance and stress tolerance , 2002, Journal of neuroscience research.
[57] Jeffrey N Keller,et al. The proteasome in brain aging , 2002, Ageing Research Reviews.
[58] C. Leeuwenburgh,et al. Aging and the Role of Reactive Nitrogen Species , 2002, Annals of the New York Academy of Sciences.
[59] M. Kim,et al. Age-related changes in the distribution of nitrotyrosine in the cerebral cortex and hippocampus of rats , 2002, Brain Research.
[60] V. Calabrese,et al. Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers. , 2002, Molecular pharmacology.
[61] M. L. Genova,et al. Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging. , 2002, Biochimica et biophysica acta.
[62] D. Geroldi,et al. ATPases enzyme activities during ageing in different types of somatic and synaptic plasma membranes from rat frontal cerebral cortex , 2002, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[63] S. Kelly,et al. Neuroprotection: Heat Shock Proteins , 2002, Current medical research and opinion.
[64] V. Calabrese,et al. Vitamin E and Neurodegenerative Disorders Associated with Oxidative Stress , 2002, Nutritional neuroscience.
[65] D. Butterfield. Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. , 2002, Free radical research.
[66] Elias S. J. Arnér,et al. Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. , 2001, Free radical biology & medicine.
[67] K. Baskerville,et al. Signatures of hippocampal oxidative stress in aged spatial learning-impaired rodents , 2001, Neuroscience.
[68] V. Kansal,et al. Age-dependent variations in mitochondrial and cytosolic antioxidant enzymes and lipid peroxidation in different regions of central nervous system of guinea pigs. , 2001, Indian journal of biochemistry & biophysics.
[69] L. Roberts,et al. Measurement of F(2)-isoprostanes unveils profound oxidative stress in aged rats. , 2001, Biochemical and biophysical research communications.
[70] E. Stadtman,et al. Oxidative modification of proteins during aging , 2001, Experimental Gerontology.
[71] S. Imam,et al. Aging increases the susceptiblity to methamphetamine‐induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia , 2001, Journal of neurochemistry.
[72] G. Spiteller. Lipid peroxidation in aging and age-dependent diseases , 2001, Experimental Gerontology.
[73] C. Richter-Landsberg,et al. Stress proteins in oligodendrocytes: differential effects of heat shock and oxidative stress , 2001, Journal of neurochemistry.
[74] T. Montine,et al. Formation of Highly Reactive γ-Ketoaldehydes (Neuroketals) as Products of the Neuroprostane Pathway* , 2001, The Journal of Biological Chemistry.
[75] D. Butterfield,et al. Glutathione elevation and its protective role in acrolein-induced protein damage in synaptosomal membranes: relevance to brain lipid peroxidation in neurodegenerative disease , 2001, Neurochemistry International.
[76] D. Allan Butterfield,et al. Brain protein oxidation in age-related neurodegenerative disorders that are associated with aggregated proteins , 2001, Mechanisms of Ageing and Development.
[77] Virginia M. Y. Lee,et al. Increased Lipid Peroxidation Precedes Amyloid Plaque Formation in an Animal Model of Alzheimer Amyloidosis , 2001, The Journal of Neuroscience.
[78] N. Ballatori,et al. Novel roles for glutathione in gene expression, cell death, and membrane transport of organic solutes. , 2001, Journal of hepatology.
[79] E. Melamed,et al. Oxidative stress induced-neurodegenerative diseases: the need for antioxidants that penetrate the blood brain barrier , 2001, Neuropharmacology.
[80] G. Spiteller. Peroxidation of linoleic acid and its relation to aging and age dependent diseases , 2001, Mechanisms of Ageing and Development.
[81] G. Storz,et al. Structural Basis of the Redox Switch in the OxyR Transcription Factor , 2001, Cell.
[82] T. Toda. Proteome and Proteomics for the Research on Protein Alterations in Aging , 2001, Annals of the New York Academy of Sciences.
[83] K. Watanabe,et al. Induction of mitochondrial heat shock protein 60 and 10 mRNAs following transient focal cerebral ischemia in the rat. , 2001, Brain research. Molecular brain research.
[84] D. Butterfield,et al. Protein oxidation in the brain in Alzheimer's disease , 2001, Neuroscience.
[85] R. Porsolt,et al. Brain and hippocampus fatty acid composition in phospholipid classes of aged-relative cognitive deficit rats. , 2001, Prostaglandins, leukotrienes, and essential fatty acids.
[86] W. Markesbery,et al. Acrolein is increased in Alzheimer’s disease brain and is toxic to primary hippocampal cultures , 2001, Neurobiology of Aging.
[87] U. Çakatay,et al. Relation of oxidative protein damage and nitrotyrosine levels in the aging rat brain , 2001, Experimental Gerontology.
[88] D. Botstein,et al. Role of thioredoxin reductase in the Yap1p‐dependent response to oxidative stress in Saccharomyces cerevisiae , 2001, Molecular microbiology.
[89] J. Bohl,et al. Immunohistochemical investigation of the brain of aged dogs. I. Detection of neurofibrillary tangles and of 4-hydroxynonenal protein, an oxidative damage product, in senile plaques , 2001, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.
[90] W. Koppenol,et al. Reaction of peroxynitrite with carbon dioxide: intermediates and determination of the yield of CO3•– and NO2• , 2001, JBIC Journal of Biological Inorganic Chemistry.
[91] T. Lüscher,et al. Enhanced Peroxynitrite Formation Is Associated with Vascular Aging , 2000, The Journal of experimental medicine.
[92] E. Hall,et al. LC-MS/MS detection of peroxynitrite-derived 3-nitrotyrosine in rat microvessels. , 2000, Free radical biology & medicine.
[93] K. Davies,et al. Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II—aging of nondividing cells , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[94] K. Davies,et al. Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I— effects of proliferative senescence , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[95] B. Fanburg,et al. Reactive oxygen species in cell signaling. , 2000, American journal of physiology. Lung cellular and molecular physiology.
[96] G. Branlant,et al. A Sulfenic Acid Enzyme Intermediate Is Involved in the Catalytic Mechanism of Peptide Methionine Sulfoxide Reductase fromEscherichia coli * , 2000, The Journal of Biological Chemistry.
[97] H. Ku,et al. Age-associated changes of superoxide dismutase and catalase activities in the rat brain. , 2000, Journal of biomedical science.
[98] W. Markesbery,et al. Acrolein, a product of lipid peroxidation, inhibits glucose and glutamate uptake in primary neuronal cultures. , 2000, Free radical biology & medicine.
[99] E. Herrero,et al. Oxidative stress promotes specific protein damage in Saccharomyces cerevisiae. , 2000, The Journal of biological chemistry.
[100] H. Schipper,et al. Heme oxygenase-1: role in brain aging and neurodegeneration , 2000, Experimental Gerontology.
[101] Y. Itoyama,et al. Increased bilirubins and their derivatives in cerebrospinal fluid in Alzheimer’s disease , 2000, Neurobiology of Aging.
[102] V. Calabrese,et al. Nitric oxide synthase induction in astroglial cell cultures: Effect on heat shock protein 70 synthesis and oxidant/antioxidant balance , 2000, Journal of neuroscience research.
[103] W. Markesbery,et al. Decreased levels of proteasome activity and proteasome expression in aging spinal cord , 2000, Neuroscience.
[104] M. Bicho,et al. Acid phosphatase, genetic polymorphism and cardiovascular risk factors in a pediatric population. , 2000, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology.
[105] J. Alam,et al. The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo. , 2000, The American journal of pathology.
[106] D. Slatter,et al. The importance of lipid-derived malondialdehyde in diabetes mellitus , 2000, Diabetologia.
[107] R. Foresti,et al. Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress. , 2000, Free radical biology & medicine.
[108] Stephen Barnes,et al. Nitric Oxide Reaction with Lipid Peroxyl Radicals Spares α-Tocopherol during Lipid Peroxidation , 2000, The Journal of Biological Chemistry.
[109] V. Calabrese,et al. HSP70 induction in the brain following ethanol administration in the rat: regulation by glutathione redox state. , 2000, Biochemical and biophysical research communications.
[110] T. Zglinicki,et al. Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts. , 2000, Free radical biology & medicine.
[111] E. Cabiscol,et al. Oxidative stress in bacteria and protein damage by reactive oxygen species. , 2000, International microbiology : the official journal of the Spanish Society for Microbiology.
[112] D. Butterfield,et al. In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brain , 2000, Neurochemistry International.
[113] J. Morrow,et al. Measurement of F(2)-isoprostanes as an index of oxidative stress in vivo. , 2000, Free radical biology & medicine.
[114] D. Betteridge,et al. What is oxidative stress? , 2000, Metabolism: clinical and experimental.
[115] W. Markesbery,et al. Possible involvement of proteasome inhibition in aging: implications for oxidative stress , 2000, Mechanisms of Ageing and Development.
[116] C. Suschek,et al. Implications of inducible nitric oxide synthase expression and enzyme activity. , 2000, Antioxidants & redox signaling.
[117] J. Eiserich,et al. Nitric oxide reaction with lipid peroxyl radicals spares alpha-tocopherol during lipid peroxidation. Greater oxidant protection from the pair nitric oxide/alpha-tocopherol than alpha-tocopherol/ascorbate. , 2000, The Journal of biological chemistry.
[118] R. Floyd. Antioxidants, oxidative stress, and degenerative neurological disorders. , 1999, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.
[119] D. Bredt. Endogenous nitric oxide synthesis: biological functions and pathophysiology. , 1999, Free radical research.
[120] R. Foresti,et al. The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis. , 1999, Free radical research.
[121] I. Fridovich. Fundamental Aspects of Reactive Oxygen Species, or What's the Matter with Oxygen? , 1999, Annals of the New York Academy of Sciences.
[122] S. Sorbi,et al. Oxidative Stress and a Key Metabolic Enzyme in Alzheimer Brains, Cultured Cells, and an Animal Model of Chronic Oxidative Deficits , 1999, Annals of the New York Academy of Sciences.
[123] B. Halliwell. Antioxidant defence mechanisms: from the beginning to the end (of the beginning). , 1999, Free radical research.
[124] B. Kalyanaraman,et al. Bicarbonate Enhances the Peroxidase Activity of Cu,Zn-Superoxide Dismutase , 1999, The Journal of Biological Chemistry.
[125] A. Dominiczak,et al. Endothelial function in hypertension: the role of superoxide anion. , 1999, Hypertension.
[126] W. Nauseef. The NADPH-dependent oxidase of phagocytes. , 1999, Proceedings of the Association of American Physicians.
[127] H. J. Kim,et al. Characterization of three isoforms of mammalian peroxiredoxin that reduce peroxides in the presence of thioredoxin. , 1999, Diabetes research and clinical practice.
[128] G. Gibson,et al. Oxidative stress is associated with region-specific neuronal death during thiamine deficiency. , 1999, Journal of neuropathology and experimental neurology.
[129] B. Mayer,et al. Enzymatic function of nitric oxide synthases. , 1999, Cardiovascular research.
[130] L. Beilin,et al. Measurement of Urinary F2-Isoprostanes as Markers of in Vivo Lipid Peroxidation—A Comparison of Enzyme Immunoassay with Gas Chromatography/Mass Spectrometry , 1999 .
[131] D. Praticò,et al. Brains of Aged Apolipoprotein E‐Deficient Mice Have Increased Levels of F2‐Isoprostanes, In Vivo Markers of Lipid Peroxidation , 1999, Journal of neurochemistry.
[132] G. Barja. Mitochondrial Oxygen Radical Generation and Leak: Sites of Production in States 4 and 3, Organ Specificity, and Relation to Aging and Longevity , 1999, Journal of bioenergetics and biomembranes.
[133] B. Halliwell. Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and the effects of nutrition. , 1999, Mutation research.
[134] M. Scheffner,et al. Activation of the Cell Death Program by Nitric Oxide Involves Inhibition of the Proteasome* , 1999, The Journal of Biological Chemistry.
[135] R. G. Paul,et al. Reactions of Lipid-derived Malondialdehyde with Collagen* , 1999, The Journal of Biological Chemistry.
[136] H. Tohgi,et al. Alterations of 3-nitrotyrosine concentration in the cerebrospinal fluid during aging and in patients with Alzheimer's disease , 1999, Neuroscience Letters.
[137] J. Sloane,et al. Increased microglial activation and protein nitration in white matter of the aging monkey☆ , 1999, Neurobiology of Aging.
[138] N. Kruger,et al. Nitrogen dioxide induces cis-trans-isomerization of arachidonic acid within cellular phospholipids. Detection of trans-arachidonic acids in vivo. , 1999, The Journal of biological chemistry.
[139] S. Brüsselbach,et al. Inhibition of D1, D2, and A-cyclin expression in HL-60 cells by the lipid peroxydation product 4-hydroxynonenal. , 1999, Free radical biology & medicine.
[140] R. Ali,et al. The aging paradox: free radical theory of aging , 1999, Experimental Gerontology.
[141] G. Storz,et al. Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[142] J. Morrow,et al. Identification of Extremely Reactive γ-Ketoaldehydes (Isolevuglandins) as Products of the Isoprostane Pathway and Characterization of Their Lysyl Protein Adducts* , 1999, The Journal of Biological Chemistry.
[143] J. Morrow,et al. Formation of Reactive Cyclopentenone Compounds in Vivo as Products of the Isoprostane Pathway* , 1999, The Journal of Biological Chemistry.
[144] H. Mühl,et al. Inducible NO synthase: role in cellular signalling. , 1999, The Journal of experimental biology.
[145] B. Babior. NADPH oxidase: an update. , 1999, Blood.
[146] F. Sharp,et al. Anti-oxidants prevent focal rat brain injury as assessed by induction of heat shock proteins (HSP70, HO-1/HSP32, HSP47) following subarachnoid injections of lysed blood. , 1999, Brain research. Molecular brain research.
[147] D. Butterfield,et al. Peroxynitrite‐Induced Alterations in Synaptosomal Membrane Proteins , 1999, Journal of neurochemistry.
[148] N. Krishna,et al. Nitration of unsaturated fatty acids by nitric oxide-derived reactive nitrogen species peroxynitrite, nitrous acid, nitrogen dioxide, and nitronium ion. , 1999, Chemical research in toxicology.
[149] S. Rhee,et al. Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin. , 1999, Methods in enzymology.
[150] J. Morrow,et al. Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress. , 1999, Methods in enzymology.
[151] L. Beilin,et al. Measurement of urinary F(2)-isoprostanes as markers of in vivo lipid peroxidation-A comparison of enzyme immunoassay with gas chromatography/mass spectrometry. , 1999, Analytical biochemistry.
[152] M. Lagarde,et al. Covalent modifications of aminophospholipids by 4-hydroxynonenal. , 1998, Free radical biology & medicine.
[153] J. Joseph,et al. Nitration of γ-tocopherol and oxidation of α-tocopherol by copper-zinc superoxide dismutase/H2O2/NO2−: Role of nitrogen dioxide free radical , 1998 .
[154] T. Montine,et al. Cerebrospinal fluid F2‐isoprostane levels are increased in Alzheimer's disease , 1998, Annals of neurology.
[155] L. Klassen,et al. Detection of circulating antibodies to malondialdehyde-acetaldehyde adducts in ethanol-fed rats. , 1998, Gastroenterology.
[156] Munehiro Yoshida,et al. A simple, rapid, highly sensitive and reproducible quantification method for plasma malondialdehyde by high-performance liquid chromatography. , 1998, Biomedical chromatography : BMC.
[157] L. Marnett,et al. Induction of cell cycle arrest by the endogenous product of lipid peroxidation, malondialdehyde. , 1998, Carcinogenesis.
[158] B. Kalyanaraman,et al. Nitric oxide and low-density lipoprotein oxidation. , 1998, Free radical research.
[159] T. Montine,et al. Formation of Isoprostane-like Compounds (Neuroprostanes) in Vivo from Docosahexaenoic Acid* , 1998, The Journal of Biological Chemistry.
[160] J. Morrow,et al. Comparison of formation of D2/E2-isoprostanes and F2-isoprostanes in vitro and in vivo--effects of oxygen tension and glutathione. , 1998, Archives of biochemistry and biophysics.
[161] K. Davies,et al. Peroxynitrite Increases the Degradation of Aconitase and Other Cellular Proteins by Proteasome* , 1998, The Journal of Biological Chemistry.
[162] E. Niki,et al. Protein-bound acrolein: potential markers for oxidative stress. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[163] M. Cappiello,et al. Site-specific inactivation of aldose reductase by 4-hydroxynonenal. , 1998, Archives of biochemistry and biophysics.
[164] E. Cabiscol,et al. Identification of the Major Oxidatively Damaged Proteins inEscherichia coli Cells Exposed to Oxidative Stress* , 1998, The Journal of Biological Chemistry.
[165] D. Butterfield,et al. Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction , 1998, Mechanisms of Ageing and Development.
[166] D. Slatter,et al. Formation of a dihydropyridine derivative as a potential cross‐link derived from malondialdehyde in physiological systems , 1998, FEBS letters.
[167] J. Morrow,et al. The Isoprostanes: Unique Bioactive Products of Lipid Peroxidation , 1997, Journal of Biomedical Science.
[168] A. Colell,et al. Oxidative stress: Role of mitochondria and protection by glutathione , 1998, BioFactors.
[169] J. Joseph,et al. Nitration of gamma-tocopherol and oxidation of alpha-tocopherol by copper-zinc superoxide dismutase/H2O2/NO2-: role of nitrogen dioxide free radical. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[170] M. Lynch. Analysis of the Mechanisms Underlying the Age-related Impairment in Long-Term Potentiation in the Rat , 1998, Reviews in the neurosciences.
[171] D. Butterfield,et al. Oxidative modification of glutamine synthetase by amyloid beta peptide. , 1997, Free radical research.
[172] I. Fridovich. Superoxide Anion Radical (O·̄2), Superoxide Dismutases, and Related Matters* , 1997, The Journal of Biological Chemistry.
[173] R. J. Herr,et al. Diastereoselective Synthesis of an Isoprostane: (.+-.)-8-epi-PFG2. alpha. Ethyl Ester. , 1997 .
[174] M. Mattson,et al. Amyloid β‐Peptide Induces Cell Monolayer Albumin Permeability, Impairs Glucose Transport, and Induces Apoptosis in Vascular Endothelial Cells , 1997 .
[175] Mark A. Smith,et al. 4‐Hydroxynonenal‐Derived Advanced Lipid Peroxidation End Products Are Increased in Alzheimer's Disease , 1997, Journal of neurochemistry.
[176] J. Morrow,et al. The generation and actions of isoprostanes. , 1997, Biochimica et biophysica acta.
[177] B. Friguet,et al. Inhibition of the multicatalytic proteinase (proteasome) by 4‐hydroxy‐2‐nonenal cross‐linked protein , 1997, FEBS letters.
[178] S. L. Fink,et al. Defective Herpes Simplex Virus Vectors Expressing the Rat Brain Stress‐Inducible Heat Shock Protein 72 Protect Cultured Neurons from Severe Heat Shock , 1997, Journal of neurochemistry.
[179] D. Butterfield,et al. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-α-phenylnitrone , 1997 .
[180] R. J. Herr,et al. Diastereoselective Synthesis of an Isoprostane: (+/-)-8-epi-PGF(2)(alpha) Ethyl Ester. , 1997, The Journal of organic chemistry.
[181] D. Butterfield,et al. Effect of 2-cyclohexene-1-one-induced glutathione diminution on ischemia/reperfusion-induced alterations in the physical state of brain synaptosomal membrane proteins and lipids , 1997, Neuroscience.
[182] D. Allan Butterfield,et al. Chapter 7 Protein Oxidation Processes in Aging Brain , 1997 .
[183] M. Maines,et al. The heme oxygenase system: a regulator of second messenger gases. , 1997, Annual review of pharmacology and toxicology.
[184] D. Butterfield,et al. Free radical oxidation of brain proteins in accelerated senescence and its modulation by N-tert-butyl-alpha-phenylnitrone. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[185] M. Mattson,et al. Amyloid beta-peptide induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells. , 1997, Journal of neurochemistry.
[186] J S Beckman,et al. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. , 1996, The American journal of physiology.
[187] D. Butterfield,et al. Prevention of Hyperoxia‐Induced Alterations in Synaptosomal Membrane‐Associated Proteins by N‐tert‐Butyl‐α‐Phenylnitrone and 4‐Hydroxy‐2,2,6,6‐Tetramethylpiperidin‐1‐oxyl (Tempol) , 1996, Journal of neurochemistry.
[188] J. Morrow,et al. Nonenzymatic Free Radical-catalyzed Generation of Thromboxane-like Compounds (Isothromboxanes) in Vivo* , 1996, The Journal of Biological Chemistry.
[189] J. Bonventre,et al. Cytosolic Phospholipase A2 (PLA2), but Not Secretory PLA2, Potentiates Hydrogen Peroxide Cytotoxicity in Kidney Epithelial Cells* , 1996, The Journal of Biological Chemistry.
[190] B. Friguet,et al. Age-related decline of rat liver multicatalytic proteinase activity and protection from oxidative inactivation by heat-shock protein 90. , 1996, Archives of biochemistry and biophysics.
[191] B. Halliwell,et al. Antioxidants in human health and disease. , 1996, Annual review of nutrition.
[192] L. Tian,et al. Age-dependent increase of indigenous dna adducts in rat brain is associated with a lipid peroxidation product , 1996, Experimental Gerontology.
[193] N. Hattori,et al. Immunohistochemical detection of 4-hydroxynonenal protein adducts in Parkinson disease. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[194] V. C. Pandey,et al. Permeability function related to cerebral microvessel enzymes during ageing in rats , 1996, International Journal of Developmental Neuroscience.
[195] A. Keller,et al. Expression of the Neuron‐Specific Enolase Gene by Rat Oligodendroglial Cells During Their Differentiation , 1996, Journal of neurochemistry.
[196] F. Sharp,et al. Astrocyte survival and HSP70 heat shock protein induction following heat shock and acidosis. , 1996, Glia.
[197] F. V. van Kuijk,et al. 4-hydroxynonenal inhibits Na(+)-K(+)-ATPase. , 1996, Free radical biology & medicine.
[198] R. S. Sohal,et al. Effect of the Spin-Trapping CompoundN-tert-Butyl-α-phenylnitrone on Protein Oxidation and Life Span , 1995 .
[199] W. Slikker,et al. Age-related changes in antioxidant enzymes, superoxide dismutase, catalase, glutathione peroxidase and glutathione in different regions of mouse brain , 1995, International Journal of Developmental Neuroscience.
[200] D. Butterfield,et al. Brain Regional Correspondence Between Alzheimer's Disease Histopathology and Biomarkers of Protein Oxidation , 1995, Journal of neurochemistry.
[201] V. Ferrans,et al. Requirement for Generation of H2O2 for Platelet-Derived Growth Factor Signal Transduction , 1995, Science.
[202] G. López,et al. Age-associated changes in the content and fatty acid composition of brain glycerophospholipids. , 1995, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.
[203] D. Butterfield,et al. Membrane protein alterations in rodent erythrocytes and synaptosomes due to aging and hyperoxia. , 1995, Biochimica et biophysica acta.
[204] M. Cini,et al. Studies on lipid peroxidation and protein oxidation in the aging brain , 1995, Neurobiology of Aging.
[205] D. Butterfield,et al. Ischemia/reperfusion-induced changes in membrane proteins and lipids of gerbil cortical synaptosomes , 1995, Neuroscience.
[206] R. S. Sohal,et al. Effect of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone on protein oxidation and life span. , 1995, Archives of biochemistry and biophysics.
[207] M. Balazy. Peroxynitrite and arachidonic acid. Identification of arachidonate epoxides. , 1994, Polish journal of pharmacology.
[208] D. Butterfield,et al. Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure. , 1994, Free radical biology & medicine.
[209] D. Macey,et al. Iron release from ferritin and its sensitivity to superoxide ions differs among vertebrates. , 1994, The Biochemical journal.
[210] J. Morrow,et al. Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. , 1994, The Journal of biological chemistry.
[211] R. S. Sohal,et al. Aging and proteolysis of oxidized proteins. , 1994, Archives of biochemistry and biophysics.
[212] G. Shah,et al. Age-related changes in tissue content of malondialdehyde-modified proteins. , 1994, Life sciences.
[213] S. Shah,et al. Evidence suggesting that iron and calcium are interrelated in oxidant-induced DNA damage. , 1993, Kidney international.
[214] Jiankang Liu,et al. Age-associated changes in superoxide dismutase activity, thiobarbituric acid reactivity and reduced glutathione level in the brain and liver in senescence accelerated mice (SAM): a comparison with ddY mice , 1993, Mechanisms of Ageing and Development.
[215] B. Ames,et al. Oxidants, antioxidants, and the degenerative diseases of aging. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[216] R. Miller,et al. Zinc protoporphyrin-IX blocks the effects of metabotropic glutamate receptor activation in the rat nucleus tractus solitarii. , 1993, Molecular pharmacology.
[217] H. Esterbauer,et al. Cytotoxicity and genotoxicity of lipid-oxidation products. , 1993, The American journal of clinical nutrition.
[218] S. Snyder,et al. Carbon monoxide: a putative neural messenger. , 1993, Science.
[219] D. Li,et al. I-compounds--endogenous DNA markers of nutritional status, ageing, tumour promotion and carcinogenesis. , 1993, IARC scientific publications.
[220] S. Agarwal,et al. Isolation of a malondialdehyde-deoxyguanosine adduct from rat liver DNA. , 1992, Free radical biology & medicine.
[221] J. Morrow,et al. Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. , 1992, The Journal of clinical investigation.
[222] Shozo Yamamoto,et al. Mammalian lipoxygenases: molecular structures and functions. , 1992, Biochimica et biophysica acta.
[223] V. Petruzzella,et al. Lipid Composition in Synaptic and Nonsynaptic Mitochondria from Rat Brains and Effect of Aging , 1992, Journal of neurochemistry.
[224] M. Marletta,et al. Nitric oxide synthase is a cytochrome P-450 type hemoprotein. , 1992, Biochemistry.
[225] B. Halliwell,et al. Biologically relevant metal ion‐dependent hydroxyl radical generation An update , 1992, FEBS letters.
[226] E. Stadtman,et al. Modification of histidine residues in proteins by reaction with 4-hydroxynonenal. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[227] W. Markesbery,et al. Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[228] I. Young,et al. Measurement of Malondialdehyde in Plasma by High Performance Liquid Chromatography with Fluorimetric Detection , 1991, Annals of clinical biochemistry.
[229] B. Freeman,et al. Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide. , 1991, Archives of biochemistry and biophysics.
[230] R. Floyd,et al. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[231] S. Hazen,et al. Activation of a membrane-associated phospholipase A2 during rabbit myocardial ischemia which is highly selective for plasmalogen substrate. , 1991, The Journal of biological chemistry.
[232] J. Remacle,et al. Cytotoxicity of linoleic acid peroxide, malondialdehyde and 4-hydroxynonenal towards human fibroblasts. , 1991, Toxicology.
[233] S. Murphy,et al. Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6). , 1991, Journal of neurochemistry.
[234] H. Esterbauer,et al. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. , 1991, Free radical biology & medicine.
[235] J. Carney. Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound n-tert-butyl-α-phenylnitrone. Proceedings of the National , 1991 .
[236] K. Ohno,et al. Quantitative determination of deleted mitochondrial DNA relative to normal DNA in parkinsonian striatum by a kinetic PCR analysis. , 1990, Biochemical and biophysical research communications.
[237] L. Ignarro. Haem-dependent activation of guanylate cyclase and cyclic GMP formation by endogenous nitric oxide: a unique transduction mechanism for transcellular signaling. , 1990, Pharmacology & toxicology.
[238] D. Li,et al. Age-related DNA modifications (I-compounds): modulation by physiological and pathological processes. , 1990, Mutation research.
[239] J L Witztum,et al. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. , 1990, Arteriosclerosis.
[240] V. Hrachovina,et al. [Lactate dehydrogenase and malate dehydrogenase activity in the glial and neuronal fractions of the brain tissue in rats of various ages]. , 1990, Sbornik lekarsky.
[241] R. Floyd,et al. Role of oxygen free radicals in carcinogenesis and brain ischemia , 1990, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[242] E. Stadtman,et al. Metal ion-catalyzed oxidation of proteins: biochemical mechanism and biological consequences. , 1990, Free radical biology & medicine.
[243] T. Gräser,et al. Study on the mechanism of carbon monoxide induced endothelium-independent relaxation in porcine coronary artery and vein. , 1990, Biomedica biochimica acta.
[244] K. V. van Golen,et al. Age-dependent covalent DNA alterations (I-compounds) in rat liver mitochondrial DNA. , 1990, Mutation research.
[245] J. Zweier,et al. Characterization of free radical generation by xanthine oxidase. Evidence for hydroxyl radical generation. , 1989, The Journal of biological chemistry.
[246] J. Liehr,et al. Age-dependent covalent DNA alterations (I-compounds) in rodent tissues: species, tissue and sex specificities. , 1989, Mutation research.
[247] V. Nair,et al. Fluorescent 1,4-Dihydropyridines: The Malondialdehyde Connection. , 1988 .
[248] R. Lehrer,et al. Human neutrophil antimicrobial activity. , 1988, Reviews of infectious diseases.
[249] G. Turner,et al. Fluorescent 1.4-Dihydropyridines: The Malondlaldehyde connection , 1988 .
[250] B. Halliwell. Oxidants and human disease: some new concepts , 1987 .
[251] F. Amenta,et al. Enzyme histochemistry of the choroid plexus in old rats , 1987, Mechanisms of Ageing and Development.
[252] V. Yong,et al. Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease , 1987, Annals of neurology.
[253] S. Wong,et al. Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. , 1987, Clinical chemistry.
[254] K. Ohta,et al. Regional Distributions of Thiobarbituric Acid‐Reactive Products, Activities of Enzymes Regulating the Metabolism of Oxygen Free Radicals, and Some of the Related Enzymes in Adult and Aged Rat Brains , 1986, Journal of neurochemistry.
[255] P. Bellavite,et al. Mechanism of production of toxic oxygen radicals by granulocytes and macrophages and their function in the inflammatory process. , 1985, Pathology, research and practice.
[256] J. Povlishock,et al. Appearance of Superoxide Anion Radical in Cerebral Extracellular Space during Increased Prostaglandin Synthesis in Cats , 1985, Circulation research.
[257] D. Steinberg,et al. Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[258] F. Schroeder,et al. Sex and age alter plasma membranes of cultured fibroblasts. , 1984, European journal of biochemistry.
[259] E. Frankel. Chemistry of free radical and singlet oxidation of lipids. , 1984, Progress in lipid research.
[260] L. Marnett,et al. Unequivocal demonstration that malondialdehyde is a mutagen. , 1983, Carcinogenesis.
[261] E. Hedegaard,et al. Nano-scale densitometric quantitation of phospholipids. , 1981, Journal of chromatography.
[262] C. S. Cooper,et al. Degenerative chemistry of malondialdehyde. Structure, stereochemistry, and kinetics of formation of enaminals from reaction with amino acids , 1981 .
[263] J. Zyren,et al. Fatty acid analysis on short glass capillary columns. , 1980, Journal of agricultural and food chemistry.
[264] F. Vitiello,et al. Thin-layer chromatography of phospholipids. , 1978, Journal of chromatography.
[265] E. Granström,et al. Radioimmunoassay of prostaglandins and thromboxanes. , 1978, Advances in prostaglandin and thromboxane research.
[266] I. Fridovich,et al. An iron-containing superoxide dismutase from Escherichia coli. , 1973, The Journal of biological chemistry.
[267] I. Fridovich,et al. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). , 1969, The Journal of biological chemistry.
[268] D. Harman. PROLONGATION OF LIFE: ROLE OF FREE RADICAL REACTIONS IN AGING , 1969, Journal of the American Geriatrics Society.
[269] King Tp. Selective chemical modification of arginyl residues. , 1966 .
[270] T. King. Selective chemical modification of arginyl residues. , 1966, Biochemistry.
[271] D. Harman. Aging: a theory based on free radical and radiation chemistry. , 1956, Journal of gerontology.