The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

[1]  D. Girelli,et al.  Novel TMPRSS6 mutations associated with iron‐refractory iron deficiency anemia (IRIDA) , 2010, Human mutation.

[2]  Inês Barroso,et al.  Genome-wide association study identifies five loci associated with lung function , 2010, Nature Genetics.

[3]  G. Cooke,et al.  MMP12, lung function, and COPD in high-risk populations. , 2010, The New England journal of medicine.

[4]  N. Laird,et al.  Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation , 2010, Respiratory research.

[5]  H. von Melchner,et al.  Inactivation of sestrin 2 induces TGF-β signaling and partially rescues pulmonary emphysema in a mouse model of COPD , 2010, Disease Models & Mechanisms.

[6]  K. Morgan,et al.  Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population , 2010, BMC Medical Genetics.

[7]  E. Silverman,et al.  MMP12, lung function, and COPD in high-risk populations. , 2009, The New England journal of medicine.

[8]  D. DeMeo,et al.  Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene. , 2009, American journal of human genetics.

[9]  D. Postma,et al.  Meta-analyses on suspected chronic obstructive pulmonary disease genes: a summary of 20 years' research. , 2009, American journal of respiratory and critical care medicine.

[10]  K. Shianna,et al.  A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci , 2009, PLoS genetics.

[11]  Tim Becker,et al.  Genetic association analysis with FAMHAP: a major program update , 2009, Bioinform..

[12]  J. Carter,et al.  Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect. , 2008, American journal of respiratory and critical care medicine.

[13]  M. Spitz,et al.  The CHRNA5-A3 region on chromosome 15q24-25.1 is a risk factor both for nicotine dependence and for lung cancer. , 2008, Journal of the National Cancer Institute.

[14]  S. Matalon,et al.  Alpha1-antitrypsin inhibits the activity of the matriptase catalytic domain in vitro. , 2008, American journal of respiratory cell and molecular biology.

[15]  G. Mills,et al.  Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1 , 2008, Nature Genetics.

[16]  C. Mathers,et al.  Projections of Global Mortality and Burden of Disease from 2002 to 2030 , 2006, PLoS medicine.

[17]  Mark Daly,et al.  Haploview: analysis and visualization of LD and haplotype maps , 2005, Bioinform..

[18]  Michael Knapp,et al.  A powerful strategy to account for multiple testing in the context of haplotype analysis. , 2004, American journal of human genetics.

[19]  Kazuhiro Iwai,et al.  Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice , 2001, Nature Genetics.

[20]  Z. Šidák.  Rectangular Confidence Regions for the Means of Multivariate Normal Distributions , 1967 .