Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas
暂无分享,去创建一个
H. J. Olverman | P. Kelly | E. Paul | C. Lowry | J. Seckl | Alon Chen | O. Issler | Y. Kuperman | R. Carter | A. Neufeld-Cohen | P. Jamieson | R. Carter
[1] E. Paul,et al. Functional topography of serotonergic systems supports the Deakin/Graeff hypothesis of anxiety and affective disorders , 2013, Journal of psychopharmacology.
[2] N. Coimbra,et al. Differential involvement of dorsal raphe subnuclei in the regulation of anxiety- and panic-related defensive behaviors , 2012, Neuroscience.
[3] Y. Li,et al. Chronic social defeat up‐regulates expression of the serotonin transporter in rat dorsal raphe nucleus and projection regions in a glucocorticoid‐dependent manner , 2012, Journal of neurochemistry.
[4] J. Vaughan,et al. Chronic Activation of Corticotropin-Releasing Factor Type 2 Receptors Reveals a Key Role for 5-HT1A Receptor Responsiveness in Mediating Behavioral and Serotonergic Responses to Stressful Challenge , 2012, Biological Psychiatry.
[5] M. Lebow,et al. Susceptibility to PTSD-Like Behavior Is Mediated by Corticotropin-Releasing Factor Receptor Type 2 Levels in the Bed Nucleus of the Stria Terminalis , 2012, The Journal of Neuroscience.
[6] C. Sandi,et al. Evidence for biological roots in the transgenerational transmission of intimate partner violence , 2012, Translational Psychiatry.
[7] G. Aston-Jones,et al. A Septal-Hypothalamic Pathway Drives Orexin Neurons, Which Is Necessary for Conditioned Cocaine Preference , 2012, The Journal of Neuroscience.
[8] G. Miller,et al. Advances in tryptophan hydroxylase‐2 gene expression regulation: New insights into serotonin–stress interaction and clinical implications , 2012, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[9] David L. Walker,et al. EFFECTS OF CONTINUOUSLY ENHANCED CORTICOTROPIN RELEASING FACTOR EXPRESSION WITHIN THE BED NUCLEUS OF THE STRIA TERMINALIS ON CONDITIONED AND UNCONDITIONED ANXIETY , 2012, Molecular Psychiatry.
[10] S. Maier,et al. Uncontrollable, But Not Controllable, Stress Desensitizes 5-HT1A Receptors in the Dorsal Raphe Nucleus , 2011, The Journal of Neuroscience.
[11] C. Winstanley,et al. Contributions of serotonin in addiction vulnerability , 2011, Neuropharmacology.
[12] E. V. Bockstaele,et al. Collateralized dorsal raphe nucleus projections: A mechanism for the integration of diverse functions during stress , 2011, Journal of Chemical Neuroanatomy.
[13] C. Lowry,et al. Topographical distribution of corticotropin-releasing factor type 2 receptor-like immunoreactivity in the rat dorsal raphe nucleus: co-localization with tryptophan hydroxylase , 2011, Neuroscience.
[14] T. Dinan,et al. Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders. , 2011, The international journal of neuropsychopharmacology.
[15] C. Nemeroff,et al. The role of corticotropin-releasing hormone in the pathophysiology of depression: therapeutic implications. , 2011, Current topics in medicinal chemistry.
[16] K. Lesch,et al. Cerebral metabolic responses to 5-HT2A/C receptor activation in mice with genetically modified serotonin transporter (SERT) expression , 2011, European Neuropsychopharmacology.
[17] A. Grace,et al. Hippocampus, amygdala, and stress: interacting systems that affect susceptibility to addiction , 2011, Annals of the New York Academy of Sciences.
[18] C. Lowry,et al. A triple urocortin knockout mouse model reveals an essential role for urocortins in stress recovery , 2010, Proceedings of the National Academy of Sciences.
[19] Alon Chen,et al. Perifornical Urocortin-3 mediates the link between stress-induced anxiety and energy homeostasis , 2010, Proceedings of the National Academy of Sciences.
[20] F. Beuschlein,et al. Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits , 2010, Molecular Psychiatry.
[21] C. Barbui,et al. Long term treatment of depression with selective serotonin reuptake inhibitors and newer antidepressants , 2010, BMJ : British Medical Journal.
[22] I. Lucki,et al. Corticotropin-releasing factor in the dorsal raphe nucleus: Linking stress coping and addiction , 2010, Brain Research.
[23] Rupert Lanzenberger,et al. The Serotonin-1A Receptor in Anxiety Disorders , 2009, Biological Psychiatry.
[24] G. Forster,et al. Corticotropin-Releasing Factor Receptor Antagonism within the Dorsal Raphe Nucleus Reduces Social Anxiety-Like Behavior after Early-Life Social Isolation , 2009, The Journal of Neuroscience.
[25] T. Bale,et al. Influence of sex and corticotropin-releasing factor pathways as determinants in serotonin sensitivity. , 2009, Endocrinology.
[26] H. J. Olverman,et al. Sex influences the effect of a lifelong increase in serotonin transporter function on cerebral metabolism , 2009, Journal of neuroscience research.
[27] E. V. Bockstaele,et al. Stress-Induced Redistribution of Corticotropin-Releasing Factor Receptor Subtypes in the Dorsal Raphe Nucleus , 2009, Biological Psychiatry.
[28] C. Lowry,et al. Acoustic stimulation in vivo and corticotropin-releasing factor in vitro increase tryptophan hydroxylase activity in the rat caudal dorsal raphe nucleus , 2009, Neuroscience Letters.
[29] Anantha Shekhar,et al. Serotonergic Systems, Anxiety, and Affective Disorder , 2008, Annals of the New York Academy of Sciences.
[30] H. J. Olverman,et al. Novel analysis for improved validity in semi-quantitative 2-deoxyglucose autoradiographic imaging , 2008, Journal of Neuroscience Methods.
[31] C. Lowry,et al. Evidence for serotonin synthesis-dependent regulation of in vitro neuronal firing rates in the midbrain raphe complex. , 2008, European journal of pharmacology.
[32] C. Lowry,et al. Corticotropin‐releasing factor in the dorsal raphe nucleus increases medial prefrontal cortical serotonin via type 2 receptors and median raphe nucleus activity , 2008, The European journal of neuroscience.
[33] F. Weiss,et al. The Dorsal Subiculum Mediates the Acquisition of Conditioned Reinstatement of Cocaine-Seeking , 2008, Neuropsychopharmacology.
[34] E. Meloni,et al. Activation of Raphe Efferents to the Medial Prefrontal Cortex by Corticotropin-Releasing Factor: Correlation with Anxiety-Like Behavior , 2008, Biological Psychiatry.
[35] D. Finn,et al. Urocortin 1 microinjection into the mouse lateral septum regulates the acquisition and expression of alcohol consumption , 2008, Neuroscience.
[36] C. H. Summers,et al. Corticotropin-releasing factor 1 and 2 receptors in the dorsal raphé differentially affect serotonin release in the nucleus accumbens. , 2008, European journal of pharmacology.
[37] T. Sharp,et al. Important messages in the 'post': recent discoveries in 5-HT neurone feedback control. , 2007, Trends in pharmacological sciences.
[38] J. Neumaier,et al. Chronic low dose ovine corticotropin releasing factor or urocortin II into the rostral dorsal raphe alters exploratory behavior and serotonergic gene expression in specific subregions of the dorsal raphe , 2007, Neuroscience.
[39] O. Jahn,et al. Differential activation of CRF receptor subtypes removes stress‐induced memory deficit and anxiety , 2007, The European journal of neuroscience.
[40] E. Zorrilla,et al. Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: Ancient CRF paralogs , 2007, Frontiers in Neuroendocrinology.
[41] C. H. Summers,et al. Corticotropin-releasing factor in the dorsal raphe elicits temporally distinct serotonergic responses in the limbic system in relation to fear behavior , 2006, Neuroscience.
[42] T. Sharp,et al. In vivo evidence that 5‐HT2C receptors inhibit 5‐HT neuronal activity via a GABAergic mechanism , 2006, British journal of pharmacology.
[43] S. O’Mara. Controlling hippocampal output: The central role of subiculum in hippocampal information processing , 2006, Behavioural Brain Research.
[44] W. Vale,et al. The Effect of Lateral Septum Corticotropin-Releasing Factor Receptor 2 Activation on Anxiety Is Modulated by Stress , 2006, The Journal of Neuroscience.
[45] E. V. Bockstaele,et al. Differential projections of dorsal raphe nucleus neurons to the lateral septum and striatum , 2006, Journal of Chemical Neuroanatomy.
[46] J. Gugten,et al. Distribution and expression of CRF receptor 1 and 2 mRNAs in the CRF over-expressing mouse brain , 2006, Brain Research.
[47] C. Lowry,et al. Evidence supporting a role for corticotropin-releasing factor type 2 (CRF2) receptors in the regulation of subpopulations of serotonergic neurons , 2006, Brain Research.
[48] A. Shekhar,et al. Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs , 2005, Neuroscience.
[49] K. L. Gardner,et al. Early life experience alters behavior during social defeat: Focus on serotonergic systems , 2005, Neuroscience.
[50] A. Weitemier,et al. Lesions of the Edinger-Westphal nucleus alter food and water consumption. , 2005, Behavioral neuroscience.
[51] G. Abbadessa,et al. Effects of swim stress and α-MSH acute pre-treatment on brain 5-HT transporter and corticosterone receptor , 2005, Pharmacology Biochemistry and Behavior.
[52] T. Sharp,et al. A role for midbrain raphe &ggr; aminobutyric acid neurons in 5-hydroxytryptamine feedback control , 2005, Neuroreport.
[53] C. Lowry,et al. Urocortin 2 increases c-Fos expression in topographically organized subpopulations of serotonergic neurons in the rat dorsal raphe nucleus , 2005, Brain Research.
[54] K. Lewis,et al. Mouse corticotropin-releasing factor receptor type 2alpha gene: isolation, distribution, pharmacological characterization and regulation by stress and glucocorticoids. , 2005, Molecular endocrinology.
[55] P. Shinnick‐Gallagher,et al. Chronic Cocaine Administration Switches Corticotropin-Releasing Factor2 Receptor-Mediated Depression to Facilitation of Glutamatergic Transmission in the Lateral Septum , 2005, The Journal of Neuroscience.
[56] Anders Hay-Schmidt,et al. Modulation of anxiety circuits by serotonergic systems , 2005, Stress.
[57] S. Maier,et al. Microinjection of urocortin 2 into the dorsal raphe nucleus activates serotonergic neurons and increases extracellular serotonin in the basolateral amygdala , 2004, Neuroscience.
[58] M. Nishiyama,et al. Urocortins and corticotropin releasing factor type 2 receptors in the hypothalamus and the cardiovascular system , 2004, Peptides.
[59] S. Maier,et al. Differential expression of 5HT‐1A, α1b adrenergic, CRF‐R1, and CRF‐R2 receptor mRNA in serotonergic, γ‐aminobutyric acidergic, and catecholaminergic cells of the rat dorsal raphe nucleus , 2004 .
[60] W. Vale,et al. Selective Activation of Corticotropin-Releasing Factor-2 Receptors on Neurochemically Identified Neurons in the Rat Dorsal Raphe Nucleus Reveals Dual Actions , 2004, The Journal of Neuroscience.
[61] W. Vale,et al. CRF and CRF receptors: role in stress responsivity and other behaviors. , 2004, Annual review of pharmacology and toxicology.
[62] B. Vanderbeek,et al. Dexamethasone exposure during the neonatal period alters ORL1 mRNA expression in the hypothalamic paraventricular nucleus and hippocampus of the adult rat. , 2003, Brain research. Developmental brain research.
[63] S. Maier,et al. Low doses of corticotropin-releasing hormone injected into the dorsal raphe nucleus block the behavioral consequences of uncontrollable stress , 2003, Behavioural Brain Research.
[64] F. Holsboer,et al. Limbic corticotropin-releasing hormone receptor 1 mediates anxiety-related behavior and hormonal adaptation to stress , 2003, Nature Neuroscience.
[65] G. Griebel,et al. Effects of the selective nonpeptide corticotropin-releasing factor receptor 1 antagonist antalarmin in the chronic mild stress model of depression in mice , 2003, Progress in Neuro-Psychopharmacology and Biological Psychiatry.
[66] Michael Davis,et al. Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxiety. , 2003, European journal of pharmacology.
[67] S. Maier,et al. Corticotropin Releasing Hormone Type 2 Receptors in the Dorsal Raphe Nucleus Mediate the Behavioral Consequences of Uncontrollable Stress , 2003, The Journal of Neuroscience.
[68] Hans-Jürgen Möller,et al. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Pharmacological Treatment of Anxiety, Obsessive-Compulsive and Post-Traumatic Stress Disorders – First Revision , 2002, The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry.
[69] T. Baram,et al. Corticotropin-Releasing Hormone (CRH) Downregulates the Function of Its Receptor (CRF1) and Induces CRF1 Expression in Hippocampal and Cortical Regions of the Immature Rat Brain , 2002, Experimental Neurology.
[70] N. Kalin,et al. Reduction of Stress-Induced Behavior by Antagonism of Corticotropin-Releasing Hormone 2 (CRH2) Receptors in Lateral Septum or CRH1 Receptors in Amygdala , 2002, The Journal of Neuroscience.
[71] F. Holsboer,et al. Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. , 2002, Current opinion in pharmacology.
[72] P. Celada,et al. Control of Dorsal Raphe Serotonergic Neurons by the Medial Prefrontal Cortex: Involvement of Serotonin-1A, GABAA, and Glutamate Receptors , 2001, The Journal of Neuroscience.
[73] George Paxinos,et al. The Mouse Brain in Stereotaxic Coordinates , 2001 .
[74] C. Donaldson,et al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[75] A. Hsueh,et al. Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor , 2001, Nature Medicine.
[76] J. Vaughan,et al. Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[77] P. Sawchenko,et al. Distribution of mRNAs encoding CRF receptors in brain and pituitary of rat and mouse , 2000, The Journal of comparative neurology.
[78] S. Lightman,et al. Corticotropin-Releasing Factor Increases In VitroFiring Rates of Serotonergic Neurons in the Rat Dorsal Raphe Nucleus: Evidence for Activation of a Topographically Organized Mesolimbocortical Serotonergic System , 2000, The Journal of Neuroscience.
[79] O. Hermanson,et al. Deletion of Crhr2 reveals an anxiolytic role for corticotropin-releasing hormone receptor-2 , 2000, Nature Genetics.
[80] Paul E. Sawchenko,et al. Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress , 2000, Nature Genetics.
[81] Susan E. Murray,et al. Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2 , 2000, Nature Genetics.
[82] K. Rice,et al. Effects of Corticotropin-Releasing Factor on Neuronal Activity in the Serotonergic Dorsal Raphe Nucleus , 2000, Neuropsychopharmacology.
[83] J. Vaughan,et al. Urocortin Expression in Rat Brain: Evidence Against a Pervasive Relationship of Urocortin‐Containing Projections With Targets Bearing Type 2 CRF Receptors , 1999, The Journal of comparative neurology.
[84] J John Mann,et al. Role of the Serotonergic System in the Pathogenesis of Major Depression and Suicidal Behavior , 1999, Neuropsychopharmacology.
[85] T. Insel,et al. Autoradiographic and in situ hybridization localization of corticotropin‐releasing factor 1 and 2 receptors in nonhuman primate brain , 1999, The Journal of comparative neurology.
[86] R. Vertes,et al. Projections of the median raphe nucleus in the rat , 1999, The Journal of comparative neurology.
[87] I. Lucki,et al. Effects of Corticotropin-Releasing Factor on Brain Serotonergic Activity , 1998, Neuropsychopharmacology.
[88] A. Arimura,et al. Distribution of urocortin‐like immunoreactivity in the central nervous system of the rat , 1998, The Journal of comparative neurology.
[89] T. Baram,et al. Corticotropin releasing factor receptor type II (CRF2) messenger ribonucleic acid levels in the hypothalamic ventromedial nucleus of the infant rat are reduced by maternal deprivation. , 1997, Endocrinology.
[90] C. Rampon,et al. Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods , 1997, Neuroscience.
[91] T. Sharp,et al. Functional Mapping of Dorsal and Median Raphe 5‐Hydroxytryptamine Pathways in Forebrain of the Rat Using Microdialysis , 1997, Journal of neurochemistry.
[92] David Lovejoy,et al. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor , 1995, Nature.
[93] E. De Souza,et al. Localization of novel corticotropin-releasing factor receptor (CRF2) mRNA expression to specific subcortical nuclei in rat brain: comparison with CRF1 receptor mRNA expression , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[94] K. Semba,et al. Extent of colocalization of serotonin and GABA in the neurons of the rat raphe nuclei , 1995, Brain Research.
[95] C. Donaldson,et al. Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[96] J. Seckl,et al. Modulation of serotonin and corticosteroid receptor gene expression in the rat hippocampus with circadian rhythm and stress. , 1995, Brain research. Molecular brain research.
[97] T. Lovenberg,et al. Cloning and characterization of a functionally distinct corticotropin-releasing factor receptor subtype from rat brain. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[98] M. Hamon,et al. Selective in vivo labelling of brain 5-HT1A receptors by [3H]WAY 100635 in the mouse. , 1994, European journal of pharmacology.
[99] T. Gray,et al. Amygdaloid CRF Pathways: Role in Autonomic, Neuroendocrine, and Behavioral Responses to Stress , 1993, Annals of the New York Academy of Sciences.
[100] K. Lewis,et al. Expression cloning of a human corticotropin-releasing-factor receptor. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[101] R. Vertes. A PHA‐L analysis of ascending projections of the dorsal raphe nucleus in the rat , 1991, The Journal of comparative neurology.
[102] G. Fink,et al. Central 5,7‐Dihydroxytryptamine Lesions Decrease Hippocampal Glucocorticoid and Mineralocorticoid Receptor Messenger Ribonucleic Acid Expression , 1990, Journal of neuroendocrinology.
[103] M. Hamon,et al. Quantitative autoradiography of multiple 5-HT1 receptor subtypes in the brain of control or 5,7-dihydroxytryptamine-treated rats , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[104] H. Steinbusch,et al. The distribution and origin of serotonin‐containing fibers in the septal area: A combined immunohistochemical and fluorescent retrograde tracing study in the rat , 1982, The Journal of comparative neurology.
[105] W. Vale,et al. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin. , 1982, Science.
[106] W. Vale,et al. Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin , 1981 .
[107] H. Steinbusch,et al. Distribution of serotonin-immunoreactivity in the central nervous system of the rat—Cell bodies and terminals , 1981, Neuroscience.
[108] H. Joosten,et al. Localization of serotonin in the central nervous system by immunohistochemistry: Description of a specific and sensitive technique and some applications , 1978, Neuroscience.
[109] F. Beuschlein,et al. Urocortin-1 and -2 double-deficient mice show robust anxiolytic phenotype and modified serotonergic activity in anxiety circuits , 2010, Molecular Psychiatry.
[110] T. Baram,et al. Corticotropin-Releasing Hormone (CRH) Downregulates the Function of Its Receptor (CRF 1 ) and Induces CRF 1 Expression in Hippocampal and Cortical Regions of the Immature Rat Brain , 2010 .
[111] D. R. Britton,et al. Effects of 5-HT-1A receptor agonists on CRF-induced behavior , 2005, Psychopharmacology.
[112] A. C. Linthorst. Chapter 4.6 – Stress, corticotropin-releasing factor and serotonergic neurotransmission , 2005 .
[113] H. J. Harris,et al. Intracellular Regeneration of Glucocorticoids by 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-1 Plays a Key Role in Regulation of the Hypothalamic-Pituitary-Adrenal Axis: Analysis of 11β-HSD-1-Deficient Mice** The Wellcome Trust supported this work through a program grant (to J.J.M. and J.R.S.) and a , 2001, Endocrinology.
[114] H. J. Harris,et al. Intracellular Regeneration of Glucocorticoids by 11β-Hydroxysteroid Dehydrogenase (11β-HSD)-1 Plays a Key Role in Regulation of the Hypothalamic-Pituitary-Adrenal Axis: Analysis of 11β-HSD-1-Deficient Mice1 , 2001 .
[115] G. Flügge. Regulation of monoamine receptors in the brain: dynamic changes during stress. , 2000, International review of cytology.
[116] A. Armario,et al. Hypothalamic-pituitary-adrenal response to chronic stress in five inbred rat strains: differential responses are mainly located at the adrenocortical level. , 1996, Neuroendocrinology.
[117] E. D. De Souza,et al. Autoradiographic localization of 3H‐paroxetine‐labeled serotonin uptake sites in rat brain , 1987, Synapse.
[118] F. Bloom,et al. Chemical and biological characterization of corticotropin releasing factor. , 1983, Recent progress in hormone research.