论文信息 - Benefits in using model based predictive control during drying and lyophilisation

Benefits in using model based predictive control during drying and lyophilisation

Since 1998 [3], the yearly mean publication rate of papers using a first principle model for control has been multiplied by 11! This increase is quiet similar to the increase of the control papers in drying based on optimal control strategies, like MPC. With 60 000 products dried and 100 dryer types used worldwide [1], a real potential exists. With control tools like MPC, it is expected that the industrial drying operation will continue to improve its energy efficiency while enhancing product quality and reducing the negative environmental impact of dryers.

[1] Pascal Dufour,et al. Control Engineering in Drying Technology: Review and Trends , 2006 .

[2] S. Joe Qin,et al. A survey of industrial model predictive control technology , 2003 .

[3] Hasan Sadikoglu,et al. Mathematical Modelling of the Primary and Secondary Drying Stages of Bulk Solution Freeze-Drying in Trays: Parameter Estimation and Model Discrimination by Comparison of Theoretical Results With Experimental Data , 1997 .

[4] Hassan Hammouri,et al. Optimal operation of sublimation time of the freeze drying process by predictive control: Application of the MPC@CB software , 2008 .