Synthesis of new tetrahydropyridopyrazine derivatives via continuous flow chemistry approach and their spectroscopic characterizations

[1]  H. Joshi,et al.  Microwave-Assisted Three-Component Domino Synthesis of Polysubstituted 4H-Pyran Derivatives and Their Anticancer Activity , 2020, Russian Journal of Organic Chemistry.

[2]  L. Mologni Inhibitors of the anaplastic lymphoma kinase , 2012, Expert opinion on investigational drugs.

[3]  R. Reynolds,et al.  Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors. , 2011, Bioorganic & medicinal chemistry.

[4]  R. Goldman,et al.  Discovery and validation of new antitubercular compounds as potential drug leads and probes. , 2009, Tuberculosis.

[5]  D. Hazuda,et al.  Dihydroxypyridopyrazine-1,6-dione HIV-1 integrase inhibitors. , 2007, Bioorganic & medicinal chemistry letters.

[6]  Steven V. Ley,et al.  Optimisation of Conditions for O‐Benzyl and N‐Benzyloxycarbonyl Protecting Group Removal using an Automated Flow Hydrogenator , 2007 .

[7]  C. Müller,et al.  Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists. , 2006, Bioorganic & medicinal chemistry.

[8]  N. J. Gaikwad,et al.  Synthesis and preliminary evaluation of some pyrazine containing thiazolines and thiazolidinones as antimicrobial agents. , 2004, Bioorganic & medicinal chemistry.

[9]  R. Chicharro,et al.  Synthesis of tri- and tetracyclic condensed quinoxalin-2-ones fused across the C-3 - N-4 bond , 2003 .

[10]  M. Goodman,et al.  Solid-phase synthesis of pyridones and pyridopyrazines as peptidomimetic scaffolds. , 1999, Organic letters.

[11]  M. Abou-Gharbia,et al.  Tetrahydropyrrolo[1,2-a]quinoxalines and tetrahydropyrrolo[1,2-a]pyrido[3,2-a]pyrazines: vascular smooth muscle relaxants and antihypertensive agents. , 1984, Journal of medicinal chemistry.

[12]  L. Trnka,et al.  Comparison of the antituberculous activity of morphazinamide and pyrazinamide on chronic experimental tuberculosis. I. The antimycobacterial efficacy made in vitro and in vivo. , 1964, Chemotherapia.

[13]  J. Christopher Orexin receptor antagonists. , 2012, Pharmaceutical patent analyst.

[14]  Jeffrey Y. Pan,et al.  Construction and validation of an automated flow hydrogenation instrument for application in high-throughput organic chemistry. , 2008, Journal of combinatorial chemistry.

[15]  Ferenc Darvas,et al.  Continuous-flow high pressure hydrogenation reactor for optimization and high-throughput synthesis. , 2006, Journal of combinatorial chemistry.