Long-term effects of 56Fe irradiation on spatial memory of mice: role of sex and apolipoprotein E isoform.

[1]  J. Raber,et al.  Apolipoprotein E isoform-dependent effects on anxiety and cognition in female TR mice , 2012, Neurobiology of Aging.

[2]  J. Fike,et al.  Irradiation enhances hippocampus‐dependent cognition in mice deficient in extracellular superoxide dismutase , 2011, Hippocampus.

[3]  Richard A Britten,et al.  Low (60 cGy) Doses of 56Fe HZE-Particle Radiation Lead to a Persistent Reduction in the Glutamatergic Readily Releasable Pool in Rat Hippocampal Synaptosomes , 2010, Radiation research.

[4]  Richard A Britten,et al.  THE IDENTIFICATION OF SERUM BIOMARKERS OF HIGH-LET RADIATION EXPOSURE AND BIOLOGICAL SEQUELAE , 2010, Health physics.

[5]  Jia Bei Wang,et al.  Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level , 2009, BMC Neuroscience.

[6]  Jacob Raber,et al.  Sex‐dependent effects of 56Fe irradiation on contextual fear conditioning in C57BL/6J mice , 2009, Hippocampus.

[7]  J. Fike,et al.  Cranial irradiation alters the behaviorally induced immediate-early gene arc (activity-regulated cytoskeleton-associated protein). , 2008, Cancer research.

[8]  J. Raber,et al.  Effects of 137Cs γ Irradiation on Cognitive Performance and Measures of Anxiety in Apoe−/− and Wild-Type Female Mice , 2008, Radiation research.

[9]  Andre Obenaus,et al.  Hippocampal Neurogenesis and Neuroinflammation after Cranial Irradiation with 56Fe Particles , 2008, Radiation research.

[10]  K. Manda,et al.  Memory impairment, oxidative damage and apoptosis induced by space radiation: Ameliorative potential of α-lipoic acid , 2008, Behavioural Brain Research.

[11]  B. Shukitt-Hale,et al.  Beneficial effects of fruit extracts on neuronal function and behavior in a rodent model of accelerated aging , 2007, Neurobiology of Aging.

[12]  J. Raber.  Role of Apolipoprotein E in Anxiety , 2007, Neural plasticity.

[13]  J. Fike,et al.  Redox changes induced in hippocampal precursor cells by heavy ion irradiation , 2007, Radiation and environmental biophysics.

[14]  B. Shukitt-Hale,et al.  Amphetamine-induced taste aversion learning in young and old F-344 rats following exposure to 56Fe particles , 2007, AGE.

[15]  J. Raber,et al.  Sex-differences in age-related cognitive decline in C57BL/6J mice associated with increased brain microtubule-associated protein 2 and synaptophysin immunoreactivity , 2006, Neuroscience.

[16]  D. Hallahan,et al.  Lithium treatment prevents neurocognitive deficit resulting from cranial irradiation. , 2006, Cancer research.

[17]  J. Raber,et al.  Sex- and APOE Isoform-Dependent Effects of Radiation on Cognitive Function , 2006, Radiation research.

[18]  M. Adams,et al.  Spatial Learning and Memory Deficits after Whole-Brain Irradiation are Associated with Changes in NMDA Receptor Subunits in the Hippocampus , 2006, Radiation research.

[19]  C. Vorhees,et al.  Morris water maze: procedures for assessing spatial and related forms of learning and memory , 2006, Nature Protocols.

[20]  Bernard M. Rabin,et al.  A Longitudinal Study of Operant Responding in RatsIrradiated when 2 Months Old , 2005, Radiation research.

[21]  E. Klann,et al.  NADPH oxidase is required for NMDA receptor‐dependent activation of ERK in hippocampal area CA1 , 2005, Journal of neurochemistry.

[22]  Bernard M. Rabin,et al.  Effects of age and diet on the heavy particle-induced disruption of operant responding produced by a ground-based model for exposure to cosmic rays , 2005, Brain Research.

[23]  S. Vandenberg,et al.  Radiation-induced impairment of hippocampal neurogenesis is associated with cognitive deficits in young mice , 2004, Experimental Neurology.

[24]  Jacob Raber,et al.  Radiation-Induced Cognitive Impairments are Associated with Changes in Indicators of Hippocampal Neurogenesis , 2004, Radiation research.

[25]  A. Blokland,et al.  Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus , 2004, Neurobiology of Disease.

[26]  M. Monje,et al.  Extreme sensitivity of adult neurogenesis to low doses of X-irradiation. , 2003, Cancer research.

[27]  B. Shukitt-Hale,et al.  Effects of exposure to 56Fe particles or protons on fixed-ratio operant responding in rats. , 2002, Journal of radiation research.

[28]  R. Pearlstein,et al.  Apolipoprotein E expression and behavioral toxicity of high charge, high energy (HZE) particle radiation. , 2002, Journal of radiation research.

[29]  E. Klann,et al.  Hippocampal memory and plasticity in superoxide dismutase mutant mice , 2002, Physiology & Behavior.

[30]  B. Shukitt-Hale,et al.  Brain Signaling and Behavioral Responses Induced by Exposure to 56Fe-Particle Radiation , 2002, Radiation research.

[31]  B. Shukitt-Hale,et al.  Effects of heavy particle irradiation and diet on amphetamine- and lithium chloride-induced taste avoidance learning in rats , 2002, Brain Research.

[32]  E. Klann,et al.  Role of reactive oxygen species in hippocampal long‐term potentiation: Contributory or inhibitory? , 2002, Journal of neuroscience research.

[33]  N. Hirokawa,et al.  MAP2 is required for dendrite elongation, PKA anchoring in dendrites, and proper PKA signal transduction , 2002, The Journal of cell biology.

[34]  George Paxinos,et al.  The Mouse Brain in Stereotaxic Coordinates , 2001 .

[35]  Brian J. Wiltgen,et al.  Sex differences, context preexposure, and the immediate shock deficit in Pavlovian context conditioning with mice. , 2001, Behavioral neuroscience.

[36]  G. Barrionuevo,et al.  Impairment of Long-term Potentiation and Associative Memory in Mice That Overexpress Extracellular Superoxide Dismutase , 2000, The Journal of Neuroscience.

[37]  B. Shukitt-Hale,et al.  Spatial Learning and Memory Deficits Induced by Exposure to Iron-56-Particle Radiation , 2000, Radiation research.

[38]  R. A. Samatovicz,et al.  Genetics and brain injury: apolipoprotein E. , 2000, The Journal of head trauma rehabilitation.

[39]  M. Mattson,et al.  A Mechanism for the Neuroprotective Effect of Apolipoprotein E , 2000, Journal of neurochemistry.

[40]  R. Mahley,et al.  Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond. , 1999, Current opinion in lipidology.

[41]  G. Dawson,et al.  Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the β-amyloid precursor protein , 1999, Neuroscience.

[42]  E. Klann,et al.  Cell-permeable scavengers of superoxide prevent long-term potentiation in hippocampal area CA1. , 1998, Journal of neurophysiology.

[43]  J. Haines,et al.  Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. , 1997, JAMA.

[44]  J. Haines,et al.  Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease: A Meta-analysis , 1997 .

[45]  A. Roses,et al.  ApoE, Alzheimer's Disease, and Recovery from Brain Stress a , 1997, Annals of the New York Academy of Sciences.

[46]  J. Poirier.  Apolipoprotein E in animal models of CNS injury and in alzheimer's disease , 1994, Trends in Neurosciences.

[47]  M. Fanselow,et al.  Acquisition of contextual Pavlovian fear conditioning is blocked by application of an NMDA receptor antagonist D,L-2-amino-5-phosphonovaleric acid to the basolateral amygdala. , 1994, Behavioral neuroscience.

[48]  J. Haines,et al.  Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.

[49]  J. Joseph,et al.  Possible "accelerated striatal aging" induced by 56Fe heavy-particle irradiation: implications for manned space flights. , 1992, Radiation research.

[50]  J. Taylor,et al.  Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system. , 1985, The Journal of clinical investigation.

[51]  B. Shukitt-Hale,et al.  Elevated plus-maze performance of Fischer-344 rats as a function of age and of exposure to 56Fe particles , 2007 .

[52]  B. Shukitt-Hale,et al.  Cognitive deficits induced by 56Fe radiation exposure. , 2003, Advances in space research : the official journal of the Committee on Space Research.

[53]  J. Sweatt,et al.  Molecular psychology: roles for the ERK MAP kinase cascade in memory. , 2002, Annual review of pharmacology and toxicology.