Temperature modulated histamine‐itch in lesional and nonlesional skin in atopic eczema – a combined psychophysical and neuroimaging study

Background: Itch is the major symptom of many allergic diseases; yet it is still difficult to measure objectively. The aim of this study was to use an evaluated itch stimulus model in lesional (LS) and nonlesional (NLS) atopic eczema (AE) skin and to characterize cerebral responses using functional magnetic resonance imaging (fMRI).

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