The Nasopulmonary Reflex in the Awake Animal

Changes in pulmonary resistance and compliance, secondary to excitation of a nasopulmonary reflex, were studied in awake and anesthetized dogs. Resistance increased in all dogs after stimulation of the nasal mucosa. Because the direction and magnitude of compliance changes varied widely in both awake and anesthetized dogs, no predictable pattern could be established. A physiologic as well as an anatomic alliance links the upper and lower parts of the respiratory tract. The pathophysiologic significance of this relationship must be determined.

[1]  J. Whicker,et al.  Long-Term Canine Tracheal Stoma , 1972, The Annals of otology, rhinology, and laryngology.

[2]  B. Drettner.  Pathophysiological Relationship between the Upper and Lower Airways , 1970, The Annals of otology, rhinology, and laryngology.

[3]  J. Kaufman,et al.  The effect of nasal and nasopharyngeal irritation on airway resistance in man. , 1969, The American review of respiratory disease.

[4]  Z. Tomori,et al.  Muscular, bronchomotor and cardiovascular reflexes elicited by mechanical stimulation of the respiratory tract , 1969, The Journal of physiology.

[5]  J. Ogura,et al.  The effect of nasal obstruction on pulmonary, airway and tissue resistance , 1968, The Laryngoscope.

[6]  K. Togawa,et al.  EXPERIMENTAL OBSERVATIONS OF THE RELATIONSHIPS BETWEEN UPPER AIRWAY OBSTRUCTION AND PULMONARY FUNCTION. , 1964, Transactions of the ... annual meeting of the American Laryngological Association. American Laryngological Association. Annual Meeting.

[7]  T. Lloyd,et al.  Evaluation of methods used in detecting changes of airway resistance in man. , 2015, The American review of respiratory disease.

[8]  J. H. Comroe,et al.  Design of a body plethysmograph for studying cardiopulmonary physiology. , 1959, Journal of applied physiology.

[9]  R. J. Harrison,et al.  The Lung: Clinical Physiology and Pulmonary Function Tests , 1956 .

[10]  T. G. Brodie,et al.  Contributions to the physiology of the lungs , 1903 .