Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation
暂无分享,去创建一个
Hong Jiang | Peter Schirmacher | Han-Woong Lee | Hiromitsu Nakauchi | Zhenyu Ju | Arnold Ganser | P. Schirmacher | A. Ganser | H. Nakauchi | J. Buer | K. Rudolph | Han-Woong Lee | A. Stępczyńska | T. Zglinicki | Z. Ju | T. von Zglinicki | A. Lechel | Hong Jiang | Jan Buer | Chunfang Wang | Thomas von Zglinicki | Aaheli Roy Choudhury | Meta W Djojosubroto | Andrea Schienke | Andre Lechel | Sonja Schaetzlein | Anna Stepczynska | Chunfang Wang | K Lenhard Rudolph | K. Rudolph | S. Schaetzlein | A. Schienke | M. Djojosubroto | Anna Stępczyńska
[1] M. Lieber,et al. Ageing, repetitive genomes and DNA damage , 2004, Nature Reviews Molecular Cell Biology.
[2] K. Udupa,et al. Effect of age on hematopoiesis in man. , 1984, Blood.
[3] C. Greider,et al. Developmental and tissue-specific regulation of mouse telomerase and telomere length. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[4] Sandy Chang,et al. Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice , 1999, Cell.
[5] John M Sedivy,et al. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). , 2004, Molecular cell.
[6] C B Harley,et al. Telomere length predicts replicative capacity of human fibroblasts. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[7] Lynda Chin,et al. p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis , 1999, Cell.
[8] R. DePinho,et al. Telomere dysfunction and evolution of intestinal carcinoma in mice and humans , 2001, Nature Genetics.
[9] L. Chin,et al. Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse , 1999, Cell.
[10] Frederick W. Alt,et al. DNA Repair, Genome Stability, and Aging , 2005, Cell.
[11] A. Wagers,et al. Cellular and Molecular Signatures of Muscle Regeneration: Current Concepts and Controversies in Adult Myogenesis , 2005, Cell.
[12] N. Carter,et al. A DNA damage checkpoint response in telomere-initiated senescence , 2003, Nature.
[13] D. Beach,et al. Absence of p21WAF1 cooperates with c-myc in bypassing Ras-induced senescence and enhances oncogenic cooperation , 2004, Oncogene.
[14] Hyeyoung Min,et al. Effects of aging on early B‐ and T‐cell development , 2005, Immunological reviews.
[15] J. Lauber,et al. Telomere shortening impairs organ regeneration by inhibiting cell cycle re‐entry of a subpopulation of cells , 2003, The EMBO journal.
[16] D. Scadden,et al. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. , 2000, Science.
[17] D. Fisher,et al. Mechanisms of Hair Graying: Incomplete Melanocyte Stem Cell Maintenance in the Niche , 2005, Science.
[18] M. Manns,et al. The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo , 2005, EMBO reports.
[19] J. Shay,et al. The two-stage mechanism controlling cellular senescence and immortalization , 1992, Experimental Gerontology.
[20] Margaret A. Strong,et al. The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability , 2001, Cell.
[21] María A Blasco,et al. Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA , 1997, Cell.
[22] Margaret A. Strong,et al. Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity , 2005, Cell.
[23] T. Vulliamy,et al. Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC , 2004, Nature Genetics.
[24] Wenyi Wei,et al. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. , 1997, Science.
[25] I. Weissman,et al. Characterization of a Population of Cells in the Bone Marrow that Phenotypically Mimics Hematopoietic Stem Cells: Resting Stem Cells or Mystery Population? , 1998, Stem cells.
[26] R. DePinho,et al. Essential role of mouse telomerase in highly proliferative organs , 1998, Nature.
[27] M. Blasco,et al. Disease states associated with telomerase deficiency appear earlier in mice with short telomeres , 1999, The EMBO journal.
[28] Lynda Chin,et al. Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice , 2000, Nature.
[29] H. Nakauchi,et al. Age-Associated Characteristics of Murine Hematopoietic Stem Cells , 2000, The Journal of experimental medicine.
[30] Stephen J. Elledge,et al. Mice Lacking p21 CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control , 1995, Cell.