Gigantism with slipped capital femoral epiphysis.

Acromegalic gigantism is rare, particularly in children. 1.2 This case is reported to cite the heretofore unreported, to our knowledge, association of a slipped capital femoral epiphysis with endogenous growth hormone excess, to discuss the possible cause-and-effect relationship, and to review briefly some of the subtle presenting features in gigantism. Report of a Case .—A white girl was initially hospitalized in May 1976, at age 13 years and 11 months, for the pinning of a slipped right capital femoral epiphysis. The right leg pain began six weeks prior to admission, after the patient fell on a stairway. Some of her physical findings suggested growth hormone excess. After a short interval, she was readmitted for a pituitary evaluation and pituitary surgery. There was a history of excess perspiration, but no history of headaches, visual difficulties, weakness, fatigability, or hirsutism. Menarche had not occurred. She had been tall since early childhood although