Statistical Models of Dengue Fever

We use Bayesian data analysis to predict dengue fever outbreaks and quantify the link between outbreaks and meteorological precursors tied to the breeding conditions of vector mosquitos. We use Hamiltonian Monte Carlo sampling to estimate a seasonal Gaussian process modeling infection rate, and aperiodic basis coefficients for the rate of an “outbreak level” of infection beyond seasonal trends across two separate regions. We use this outbreak level to estimate an autoregressive moving average (ARMA) model from which we extrapolate a forecast. We show that the resulting model has useful forecasting power in the 6–8 week range. The forecasts are not significantly more accurate with the inclusion of meteorological covariates than with infection trends alone.

[1]  S. Hales,et al.  Potential effect of population and climate changes on global distribution of dengue fever: an empirical model , 2002, The Lancet.

[2]  Daniel P Weikel,et al.  Phenomenological forecasting of disease incidence using heteroskedastic Gaussian processes: a dengue case study , 2017, 1702.00261.

[3]  Richard K. Kiang,et al.  Modeling and Predicting Seasonal Influenza Transmission in Warm Regions Using Climatological Parameters , 2010, PloS one.

[4]  Sasikiran Kandula,et al.  Superensemble forecasts of dengue outbreaks , 2016, Journal of The Royal Society Interface.

[5]  Cameron P. Simmons,et al.  Current concepts: Dengue , 2012 .

[6]  Lakshminarayanan Subramanian,et al.  Characterizing dengue spread and severity using internet media sources , 2013, ACM DEV '13.

[7]  Erhan Guven,et al.  Ensemble method for dengue prediction , 2018, PloS one.

[8]  Anna L. Buczak,et al.  A data-driven epidemiological prediction method for dengue outbreaks using local and remote sensing data , 2012, BMC Medical Informatics and Decision Making.

[9]  Hiroki Masui,et al.  Assessing potential countermeasures against the dengue epidemic in non-tropical urban cities , 2016, Theoretical Biology and Medical Modelling.

[10]  Michelle L. Kirian,et al.  Prediction of gastrointestinal disease with over-the-counter diarrheal remedy sales records in the San Francisco Bay Area , 2010, BMC Medical Informatics Decis. Mak..

[11]  Evan L. Ray,et al.  Infectious disease prediction with kernel conditional density estimation , 2017, Statistics in medicine.

[12]  Gerard Borsboom,et al.  Forecasting malaria incidence from historical morbidity patterns in epidemic‐prone areas of Ethiopia: a simple seasonal adjustment method performs best , 2002, Tropical medicine & international health : TM & IH.

[13]  Julie E Shortridge,et al.  Public health and pipe breaks in water distribution systems: analysis with internet search volume as a proxy. , 2014, Water research.

[14]  Derek A T Cummings,et al.  Prospective forecasts of annual dengue hemorrhagic fever incidence in Thailand, 2010–2014 , 2018, Proceedings of the National Academy of Sciences.

[15]  Lakshminarayanan Subramanian,et al.  Fine-grained dengue forecasting using telephone triage services , 2016, Science Advances.