Patterns of DSM-IV alcohol abuse and dependence criteria among adolescents and adults: results from the 2001 National Household Survey on Drug Abuse.

BACKGROUND Studies of the prevalence of DSM-IV alcohol use disorders (AUDs) in general population samples of adolescents and adults are rare. Comparisons of the prevalence of alcohol abuse and dependence in adolescent surveys with the prevalence in adult general population surveys are confounded by differences in survey design and measurement, thereby reducing their validity. The purpose of the present study was to examine the effects of age, sex, race/ethnicity, and drinking status on the prevalence of DSM-IV alcohol abuse and dependence (including diagnostic orphans) and associated diagnostic criteria among adolescents and adults aged 12-65 years in a single representative sample of the US population. METHODS This study was based on data from the 2001 National Household Survey on Drug Abuse public use file. Of the 55,561 subjects in the survey, 33,576 (60.5%) reported alcohol use in the past year and provided information on DSM-IV AUD criteria. DSM-IV AUD criteria were assessed by questions related to specific symptoms occurring during the past 12 months. RESULTS Overall, the most prevalent criteria of DSM-IV alcohol dependence were "tolerance" and "time spent obtaining alcohol, drinking, or getting over its effects." The most prevalent criterion of DSM-IV alcohol abuse was "hazardous use." The prevalence of alcohol abuse only and of dependence with and without abuse was highest among respondents aged 18-23 years, followed by respondents aged 12-17 years, and lowest among respondents aged 50 years and older. Among subgroups of current and heavier drinkers, differences between adolescents and young adults were less pronounced, especially among females. For each age group, the prevalence of alcohol abuse only was greater than the prevalence of dependence (with or without abuse). The abuse-to-dependence ratios also were generally consistent across age groups and slightly higher among males (2.1:1.0) than females (1.6:1.0). CONCLUSIONS The higher prevalence for some dependence criteria among adolescents and young adults as measured in the present study may blur the distinction between symptom reports associated with the normative development of drinking patterns and clinically relevant aspects of DSM-IV alcohol dependence.

[1]  B. Grant,et al.  The 12-Month Prevalence and Trends in DSM–IV Alcohol Abuse and Dependence , 2004, Drug and alcohol dependence.

[2]  M. Schuckit,et al.  A five-year prospective study of diagnostic orphans for alcohol use disorders. , 2003, Journal of studies on alcohol.

[3]  J. Anthony,et al.  Possible age-associated bias in reporting of clinical features of drug dependence: epidemiological evidence on adolescent-onset marijuana use. , 2003, Addiction.

[4]  E. Wagner,et al.  Racial/ethnic and gender differences in the incidence and onset age of DSM-IV alcohol use disorder symptoms among adolescents. , 2002, Journal of studies on alcohol.

[5]  T. Chung,et al.  Prevalence of DSM-IV alcohol diagnoses and symptoms in adolescent community and clinical samples. , 2002, Journal of the American Academy of Child and Adolescent Psychiatry.

[6]  T. Chung,et al.  Concurrent and discriminant validity of DSM-IV symptoms of impaired control over alcohol consumption in adolescents. , 2002, Alcoholism, clinical and experimental research.

[7]  J. Anthony,et al.  From First Drug Use to Drug Dependence: Developmental Periods of Risk for Dependence upon Marijuana, Cocaine, and Alcohol , 2002, Neuropsychopharmacology.

[8]  K. Lynch,et al.  Health problems in adolescents with alcohol use disorders: self-report, liver injury, and physical examination findings and correlates. , 2001, Alcoholism, clinical and experimental research.

[9]  B. Muthén,et al.  The dimensionality of alcohol abuse and dependence: a multivariate analysis of DSM-IV symptom items in the National Longitudinal Survey of Youth. , 2001, Journal of studies on alcohol.

[10]  K. Winters,et al.  Assessment of alcohol tolerance in adolescents. , 2001, Journal of studies on alcohol.

[11]  K. Bucholz,et al.  Using cluster analysis of alcohol use disorders to investigate 'diagnostic orphans': subjects with alcohol dependence symptoms but no diagnosis. , 2000, Drug and alcohol dependence.

[12]  M. Schuckit,et al.  The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders. , 2000, Journal of studies on alcohol.

[13]  D. Dawson,et al.  The link between family history and early onset alcoholism: earlier initiation of drinking or more rapid development of dependence? , 2000, Journal of studies on alcohol.

[14]  B. Muthén,et al.  Integrating person-centered and variable-centered analyses: growth mixture modeling with latent trajectory classes. , 2000, Alcoholism, clinical and experimental research.

[15]  P. Schnurr,et al.  Risk factors for adolescent substance abuse and dependence: data from a national sample. , 2000, Journal of consulting and clinical psychology.

[16]  B. Muthén,et al.  The development of heavy drinking and alcohol-related problems from ages 18 to 37 in a U.S. national sample. , 2000, Journal of studies on alcohol.

[17]  K. Kendler,et al.  A multivariate genetic analysis of the use of tobacco, alcohol, and caffeine in a population based sample of male and female twins. , 1999, Drug and alcohol dependence.

[18]  C. Martin,et al.  Diagnostic orphans: adolescents with alcohol symptom who do not qualify for DSM-IV abuse or dependence diagnoses. , 1999, The American journal of psychiatry.

[19]  D. Hasin,et al.  Dependence symptoms but no diagnosis: diagnostic 'orphans' in a 1992 national sample. , 1999, Drug and alcohol dependence.

[20]  K. Kendler,et al.  Age at first drink and risk for alcoholism: a noncausal association. , 1999, Alcoholism, clinical and experimental research.

[21]  T. Beebe,et al.  DSM-IV substance use disorder criteria for adolescents: a critical examination based on a statewide school survey. , 1998, The American journal of psychiatry.

[22]  D. Hasin,et al.  Dependence symptoms but no diagnosis: diagnostic 'orphans' in a community sample. , 1998, Drug and alcohol dependence.

[23]  R. Caetano,et al.  Prevalence, incidence and stability of drinking problems among whites, blacks and Hispanics: 1984-1992. , 1997, Journal of studies on alcohol.

[24]  M. Bates,et al.  Adolescent risk factors and the prediction of persistent alcohol and drug use into adulthood. , 1997, Alcoholism, clinical and experimental research.

[25]  James W. Langenbucher,et al.  Alcohol Abuse: Adding Content to Category , 1996 .

[26]  T. Chung,et al.  Staging in the onset of DSM-IV alcohol symptoms in adolescents: survival/ hazard analyses. , 1996, Journal of studies on alcohol.

[27]  S. Maisto,et al.  Patterns of DSM-IV alcohol abuse and dependence symptoms in adolescent drinkers. , 1995, Journal of studies on alcohol.

[28]  T. Chung,et al.  Onset and staging of DSM-IV alcohol dependence using mean age and survival-hazard methods. , 1995, Journal of abnormal psychology.

[29]  D. Kandel,et al.  The natural history of drug use from adolescence to the mid-thirties in a general population sample. , 1995, American journal of public health.

[30]  R. Kessler,et al.  Lifetime and 12-month prevalence of DSM-III-R psychiatric disorders in the United States. Results from the National Comorbidity Survey. , 1994, Archives of general psychiatry.

[31]  Jacob Cohen,et al.  An epidemiological study of disorders in late childhood and adolescence--I. Age- and gender-specific prevalence. , 1993, Journal of child psychology and psychiatry, and allied disciplines.

[32]  C. G. Costello Research on Symptoms Versus Research on Syndromes , 1992, British Journal of Psychiatry.

[33]  P. Albert,et al.  Models for longitudinal data: a generalized estimating equation approach. , 1988, Biometrics.

[34]  S. Zeger,et al.  Longitudinal data analysis using generalized linear models , 1986 .