The prostaglandin EP4 receptor is a master regulator of the expression of PGE2 receptors following inflammatory activation in human monocytic cells.
暂无分享,去创建一个
[1] A. Manning-Boğ,et al. Suppression of Inflammation with Conditional Deletion of the Prostaglandin E2 EP2 Receptor in Macrophages and Brain Microglia , 2013, The Journal of Neuroscience.
[2] E. Taylor,et al. Ca2+ signals evoked by histamine H1 receptors are attenuated by activation of prostaglandin EP2 and EP4 receptors in human aortic smooth muscle cells , 2013, British journal of pharmacology.
[3] K. Iwatsubo,et al. The Prostanoid EP4 Receptor and Its Signaling Pathway , 2013, Pharmacological Reviews.
[4] D. Rotondo,et al. Characterisation of the prostaglandin E2-ethanolamide suppression of tumour necrosis factor-α production in human monocytic cells. , 2013, Biochimica et biophysica acta.
[5] H. Leaver,et al. Therapeutic implications of disorders of cell death signalling: membranes, micro‐environment, and eicosanoid and docosanoid metabolism , 2012, British journal of pharmacology.
[6] Baohong Zhang,et al. miRDeepFinder: a miRNA analysis tool for deep sequencing of plant small RNAs , 2012, Plant Molecular Biology.
[7] V. Beneš,et al. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. , 2009, Clinical chemistry.
[8] J. Albina,et al. Prostaglandin E2 Suppresses Lipopolysaccharide-Stimulated IFN-β Production1 , 2008, The Journal of Immunology.
[9] I. Dougall,et al. Activation of E-prostanoid4 and E-prostanoid2 receptors inhibits TNF-α release from human alveolar macrophages , 2007, European Respiratory Journal.
[10] A. Mancini,et al. Early Growth Response Factor-1 Mediates Prostaglandin E2-dependent Transcriptional Suppression of Cytokine-induced Tumor Necrosis Factor-α Gene Expression in Human Macrophages and Rheumatoid Arthritis-affected Synovial Fibroblasts* , 2005, Journal of Biological Chemistry.
[11] R. Young. Discovery and Synthesis of a Potent, Selective and Orally Bioavailable EP4 Receptor Agonist , 2004 .
[12] W. Walker,et al. Prostaglandin E2 is a potent regulator of interleukin‐12‐ and interleukin‐18‐induced natural killer cell interferon‐γ synthesis , 2004, Immunology.
[13] D. Ganea,et al. Prostaglandin E2 inhibits TNF production in murine bone marrow-derived dendritic cells. , 2003, Cellular immunology.
[14] Thomas D. Schmittgen,et al. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.
[15] B. Koller,et al. Receptors for prostaglandin E(2) that regulate cellular immune responses in the mouse. , 2001, The Journal of clinical investigation.
[16] Soken Tsuchiya,et al. The Expression of Prostaglandin E Receptors EP2 and EP4 and Their Different Regulation by Lipopolysaccharide in C3H/HeN Peritoneal Macrophages1 , 2001, The Journal of Immunology.
[17] Y. Sugimoto,et al. Prostaglandin E(2) receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. , 2000, Biochemical and biophysical research communications.
[18] S. Al-Sedairy,et al. A carbocyclic nucleoside analogue is a TNF-alpha inhibitor with immunosuppressive action: role of prostaglandin E2 and protein kinase C and comparison with pentoxifylline. , 1998, Cellular immunology.
[19] P. Barnes,et al. Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide‐induced tumour necrosis factor‐α generation , 1997, British journal of pharmacology.
[20] K. Seibert,et al. Selective neutralization of prostaglandin E2 blocks inflammation, hyperalgesia, and interleukin 6 production in vivo , 1996, The Journal of experimental medicine.
[21] R. L. Jones,et al. Potentiation of aggregation and inhibition of adenylate cyclase in human platelets by prostaglandin E analogues , 1993, British journal of pharmacology.
[22] W. Dröge,et al. Tumor necrosis factor-induced activation of peritoneal macrophages is regulated by prostaglandin E2 and cAMP. , 1988, Journal of immunology.
[23] D. Remick,et al. Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression. , 1988, The Journal of biological chemistry.
[24] J. Larrick,et al. Regulation of macrophage tumor necrosis factor production by prostaglandin E2. , 1986, Biochemical and biophysical research communications.
[25] I. Mlinarič-Raščan,et al. Structural features of subtype-selective EP receptor modulators. , 2017, Drug discovery today.