Spontaneous Arrest of Sporadic Spinal Hemangioblastoma Growth after Postoperative Nodular Recurrence: Case Report

Hemangioblastomas are rare, slow-growing, highly vascularized tumors of the central nervous system which often occur in the spinal cord. When presenting as sporadic, isolated tumors without Von-Hippel Lindau disease, they are curable through surgery with a low rate of recurrence. Tumor recurrence in these cases is usually associated with prior subtotal resection. However, to the best of our knowledge, cases of recurrent, sporadic spinal hemangioblastoma have not been reported to spontaneously arrest without intervention or symptoms. We report a patient who underwent an initial complete resection of a cervical spinal hemangioblastoma, a subtotal resection of tumor recurrence four and a half years later, and nine years of neurologic and radiographic stability with no additional interventions.

[1]  Meic H. Schmidt,et al.  The genetic basis of intradural spinal tumors and its impact on clinical treatment. , 2015, Neurosurgical focus.

[2]  M. Pamir,et al.  Sporadic spinal hemangioblastomas can be effectively treated by microsurgery alone. , 2014, World neurosurgery.

[3]  M. Reni,et al.  Mechanisms, indications and results of salvage systemic therapy for sporadic and von Hippel-Lindau related hemangioblastomas of the central nervous system. , 2013, Critical reviews in oncology/hematology.

[4]  Chang Hyun Park,et al.  Surgical Outcome of Spinal Cord Hemangioblastomas , 2012, Journal of Korean Neurosurgical Society.

[5]  U. Bürgel,et al.  Intramedullary hemangioblastomas: timing of surgery, microsurgical technique and follow-up in 23 patients , 2008, European Spine Journal.

[6]  D. Yoon,et al.  Surgical management of spinal cord haemangioblastoma , 2008, Acta Neurochirurgica.

[7]  L. Malis Atraumatic bloodless removal of intramedullary hemangioblastomas of the spinal cord. , 2002, Journal of neurosurgery.

[8]  R. Harden,et al.  Complex regional pain syndrome. , 2001, British journal of anaesthesia.

[9]  C. L. White,et al.  Recurrent (Nonfamilial) Hemangioblastomas Involving Spinal Nerve Roots: Case Report , 2000, Neurosurgery.

[10]  C. Kruchko,et al.  CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. , 2012, Neuro-oncology.

[11]  Kim Js,et al.  Sporadic spinal hemangioblastomas can be effectively treated by microsurgery alone. , 2011 .

[12]  N. Saito,et al.  Comparative analysis of spinal hemangioblastomas in sporadic disease and Von Hippel-Lindau syndrome. , 2010, Neurologia medico-chirurgica.