Use of proton pump inhibitors is associated with increased mortality due to nosocomial pneumonia in bedridden patients receiving tube feeding

To investigate the association between the use of proton pump inhibitors (PPI) and nosocomial pneumonia and gastrointestinal bleeding in bedridden patients receiving tube feeding.

[1]  M. Chou,et al.  Association of Proton Pump Inhibitors Usage with Risk of Pneumonia in Dementia Patients , 2017, Journal of the American Geriatrics Society.

[2]  Y. Amano,et al.  Therapeutic effects of mosapride citrate and lansoprazole for prevention of aspiration pneumonia in patients receiving gastrostomy feeding , 2013, Journal of Gastroenterology.

[3]  J. Rassen,et al.  Type of stress ulcer prophylaxis and risk of nosocomial pneumonia in cardiac surgical patients: cohort study , 2013, BMJ : British Medical Journal.

[4]  M. Howell,et al.  Erratum to: Risk Factors for Nosocomial Gastrointestinal Bleeding and Use of Acid-Suppressive Medication in Non-Critically Ill Patients , 2013, Journal of General Internal Medicine.

[5]  H. Arai,et al.  Survival period after tube feeding in bedridden older patients , 2012, Geriatrics & gerontology international.

[6]  Sang-Soo Lee,et al.  Risk of fracture and pneumonia from acid suppressive drugs. , 2011, World journal of methodology.

[7]  K. Murakami,et al.  Prevalence and independent factors for gastroduodenal ulcers/erosions in asymptomatic patients taking low-dose aspirin and gastroprotective agents: the OITA-GF study. , 2011, QJM : monthly journal of the Association of Physicians.

[8]  Charles J. Kahi,et al.  ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use , 2010, The American Journal of Gastroenterology.

[9]  Tasbirul Islam,et al.  Nosocomial Pneumonia Risk and Stress Ulcer Prophylaxis , 2010 .

[10]  R. Hunt,et al.  International Consensus Recommendations on the Management of Patients With Nonvariceal Upper Gastrointestinal Bleeding , 2010, Annals of Internal Medicine.

[11]  Michael D Howell,et al.  Acid-suppressive medication use and the risk for hospital-acquired pneumonia. , 2009, JAMA.

[12]  T. Kubo,et al.  Long‐term outcome after placement of a percutaneous endoscopic gastrostomy tube , 2008, Geriatrics & gerontology international.

[13]  A. E. El Solh,et al.  Pharmacologic prevention of aspiration pneumonia: a systematic review. , 2007, The American journal of geriatric pharmacotherapy.

[14]  S. Stawicki,et al.  Complications related to percutaneous endoscopic gastrostomy (PEG) tubes. A comprehensive clinical review. , 2007, Journal of gastrointestinal and liver diseases : JGLD.

[15]  H. Arai,et al.  MOSAPRIDE CITRATE PROLONGS SURVIVAL IN STROKE PATIENTS WITH GASTROSTOMY , 2007, Journal of the American Geriatrics Society.

[16]  R. Regal,et al.  Acid Suppressive Therapy Use on an Inpatient Internal Medicine Service , 2006, The Annals of pharmacotherapy.

[17]  D. Yadav,et al.  Gastrostomy, esophagitis, and gastrointestinal bleeding in older adults. , 2004, Journal of the American Medical Directors Association.

[18]  W. Graninger,et al.  Omeprazole treatment diminishes intra- and extracellular neutrophil reactive oxygen production and bactericidal activity* , 2002, Critical care medicine.

[19]  R. Vender,et al.  Overuse of acid-suppressive therapy in hospitalized patients , 2000, American Journal of Gastroenterology.

[20]  A. Hawthorne,et al.  Long-term outcome of percutaneous endoscopic gastrostomy feeding in patients with dysphagic stroke. , 1998, Age and ageing.

[21]  C. Aybay,et al.  The effect of omeprazole on human natural killer cell activity. , 1995, General pharmacology.

[22]  B. Garvey,et al.  Effects of gastric alkalization on bacterial colonization in critically ill patients. , 1989, Critical care medicine.

[23]  M. Howell,et al.  Risk Factors for Nosocomial Gastrointestinal Bleeding and Use of Acid-Suppressive Medication in Non-Critically Ill Patients , 2012, Journal of General Internal Medicine.