An elastic liposomal formulation for RNAi-based topical treatment of skin disorders: Proof-of-concept in the treatment of psoriasis.

[1]  S. Bracke,et al.  Characterization data on the topical carrier DDC642 , 2016, Data in brief.

[2]  A. Molinari,et al.  Liposomes as nanomedical devices , 2015, International journal of nanomedicine.

[3]  R. Hickerson,et al.  In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[4]  S. Mitragotri,et al.  Topical delivery of siRNA into skin using SPACE-peptide carriers. , 2014, Journal of controlled release : official journal of the Controlled Release Society.

[5]  S. Bracke,et al.  Targeted silencing of DEFB4 in a bioengineered skin‐humanized mouse model for psoriasis: development of siRNA SECosome‐based novel therapies , 2014, Experimental dermatology.

[6]  Christopher H Contag,et al.  Gene Silencing in Skin After Deposition of Self-Delivery siRNA With a Motorized Microneedle Array Device , 2013, Molecular therapy. Nucleic acids.

[7]  M. Singh,et al.  Novel colloidal carriers for psoriasis: current issues, mechanistic insight and novel delivery approaches. , 2013, Journal of controlled release : official journal of the Controlled Release Society.

[8]  S. Ghanbarzadeh,et al.  Enhanced Transdermal Delivery of Diclofenac Sodium via Conventional Liposomes, Ethosomes, and Transfersomes , 2013, BioMed research international.

[9]  S. Bracke,et al.  Identifying targets for topical RNAi therapeutics in psoriasis: assessment of a new in vitro psoriasis model , 2013, Archives of Dermatological Research.

[10]  O. De Wever,et al.  miR-145 overexpression suppresses the migration and invasion of metastatic melanoma cells. , 2013, International journal of oncology.

[11]  A. Attama,et al.  Lipid Nanoparticulate Drug Delivery Systems: A Revolution in Dosage Form Design and Development , 2012 .

[12]  P. Mura,et al.  Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib , 2012, Drug delivery.

[13]  J. Chen,et al.  Progress on RNAi-based molecular medicines , 2012, International journal of nanomedicine.

[14]  S. Mitragotri,et al.  Delivery of siRNA and other macromolecules into skin and cells using a peptide enhancer , 2011, Proceedings of the National Academy of Sciences.

[15]  Daniel A. Balazs,et al.  Liposomes for Use in Gene Delivery , 2010, Journal of drug delivery.

[16]  S. D. De Smedt,et al.  Flexible Nanosomes (SECosomes) Enable Efficient siRNA Delivery in Cultured Primary Skin Cells and in the Viable Epidermis of Ex Vivo Human Skin , 2010 .

[17]  R. Patlolla,et al.  Interaction of nanoparticles and cell-penetrating peptides with skin for transdermal drug delivery , 2010, Molecular membrane biology.

[18]  D. Leake,et al.  Silencing of reporter gene expression in skin using siRNAs and expression of plasmid DNA delivered by a soluble protrusion array device (PAD). , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[19]  V. Torchilin,et al.  Intracellular transduction using cell-penetrating peptides. , 2010, Molecular bioSystems.

[20]  J. Lambert,et al.  Cutaneous short-interfering RNA therapy , 2009, Expert opinion on drug delivery.

[21]  Andrea W. M. Evers,et al.  β-Defensin-2 Protein Is a Serum Biomarker for Disease Activity in Psoriasis and Reaches Biologically Relevant Concentrations in Lesional Skin , 2009, PloS one.

[22]  J. Lambert,et al.  Knockdown of myosin Va isoforms by RNAi as a tool to block melanosome transport in primary human melanocytes. , 2008, The Journal of investigative dermatology.

[23]  G. E. El Maghraby,et al.  Liposomes and skin: from drug delivery to model membranes. , 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[24]  J. Hadgraft,et al.  Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants , 2007, The Journal of pharmacy and pharmacology.

[25]  P. Janson,et al.  MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis? , 2007, PloS one.

[26]  O. Abdallah,et al.  Deformable liposomes and ethosomes as carriers for skin delivery of ketotifen. , 2007, Die Pharmazie.

[27]  Y. Tsutsumi,et al.  Creation of novel cell-penetrating peptides for intracellular drug delivery using systematic phage display technology originated from Tat transduction domain. , 2007, Biological & pharmaceutical bulletin.

[28]  M. Manoharan,et al.  RNAi therapeutics: a potential new class of pharmaceutical drugs , 2006, Nature chemical biology.

[29]  M. L. González-Rodríguez,et al.  Effect of cholesterol and ethanol on dermal delivery from DPPC liposomes. , 2005, International journal of pharmaceutics.

[30]  L. Schwichtenberg,et al.  Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid. , 2004, The Journal of investigative dermatology.

[31]  Y. Barenholz,et al.  Nanostructure of cationic lipid-oligonucleotide complexes. , 2004, Biophysical journal.

[32]  W. Ahn,et al.  Enhanced p53 gene transfer to human ovarian cancer cells using the cationic nonviral vector, DDC. , 2003, Gynecologic oncology.

[33]  F. Speleman,et al.  Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes , 2002, Genome Biology.

[34]  A. Ulrich Biophysical Aspects of Using Liposomes as Delivery Vehicles , 2002, Bioscience reports.

[35]  Frank Speleman,et al.  Elimination of primer-dimer artifacts and genomic coamplification using a two-step SYBR green I real-time RT-PCR. , 2002, Analytical biochemistry.

[36]  P. Cullis,et al.  On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids , 2001, Gene Therapy.

[37]  T. Tuschl,et al.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.

[38]  J. Rothbard,et al.  Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation , 2000, Nature Medicine.

[39]  C. Socaciu,et al.  Competitive carotenoid and cholesterol incorporation into liposomes: effects on membrane phase transition, fluidity, polarity and anisotropy. , 2000, Chemistry and physics of lipids.

[40]  B. Godin,et al.  Ethosomes - novel vesicular carriers for enhanced delivery: characterization and skin penetration properties. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[41]  B. Battersby,et al.  Lipid-DNA complex formation: reorganization and rupture of lipid vesicles in the presence of DNA as observed by cryoelectron microscopy. , 1999, Biophysical journal.

[42]  Y. Barenholz,et al.  Electrostatic and structural properties of complexes involving plasmid DNA and cationic lipids commonly used for gene delivery. , 1998, Biochimica et biophysica acta.

[43]  F. Szoka,et al.  Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. , 1996, Biochemistry.

[44]  B. Gilchrest,et al.  Pigment content of cultured human melanocytes does not correlate with tyrosinase message level , 1991, The British journal of dermatology.

[45]  H. Green,et al.  Seria cultivation of strains of human epidemal keratinocytes: the formation keratinizin colonies from single cell is , 1975, Cell.

[46]  J. Vandesompele,et al.  Identification of miR-145 as a key regulator of the pigmentary process. , 2013, The Journal of investigative dermatology.

[47]  Arthur G Erdman,et al.  The big picture on nanomedicine: the state of investigational and approved nanomedicine products. , 2013, Nanomedicine : nanotechnology, biology, and medicine.

[48]  N. Seth,et al.  Formulation and Evaluation of Elastic Liposomes of Clotrimazole , 2012 .

[49]  Carol Davila,et al.  ELASTIC VESICLES AS DRUGS CARRIERS THROUGH THE SKIN , 2010 .

[50]  André Reis,et al.  Psoriasis is associated with increased β-defensin genomic copy number , 2008, Nature Genetics.

[51]  M. Reza Mozafari,et al.  Nanomaterials and nanosystems for biomedical applications , 2007 .

[52]  Chong-Kook Kim,et al.  Effect of edge activators on the formation and transfection efficiency of ultradeformable liposomes. , 2005, Biomaterials.

[53]  H. Benson,et al.  Transdermal drug delivery: penetration enhancement techniques. , 2005, Current drug delivery.

[54]  I. Kwon,et al.  Optimization of Lipid Composition in Cationic Emulsion as In Vitro and In Vivo Transfection Agents , 2004, Pharmaceutical Research.

[55]  Chong-K. Kim,et al.  In vitro and in vivo transfection efficiency of a novel ultradeformable cationic liposome. , 2004, Biomaterials.

[56]  W. Ahn,et al.  Nonviral vector for efficient gene transfer to human ovarian adenocarcinoma cells. , 2002, Gynecologic oncology.

[57]  G. Cevc Transfersomes, liposomes and other lipid suspensions on the skin: permeation enhancement, vesicle penetration, and transdermal drug delivery. , 1996, Critical reviews in therapeutic drug carrier systems.

[58]  T. McIntosh,et al.  [38] Depth of water penetration into lipid bilayers , 1986 .