Mitochondrial detachment of hexokinase 1 in mood and psychotic disorders: implications for brain energy metabolism and neurotrophic signaling.
暂无分享,去创建一个
[1] Pierre J Magistretti,et al. In Vivo Evidence for Lactate as a Neuronal Energy Source , 2011, The Journal of Neuroscience.
[2] C. Konradi,et al. Mitochondrial dysfunction and pathology in bipolar disorder and schizophrenia , 2011, International Journal of Developmental Neuroscience.
[3] S. Dittmann,et al. Cognitive abilities and clinical variables in bipolar I depressed and euthymic patients and controls. , 2011, Journal of Psychiatric Research.
[4] Jesús Pujol,et al. Cross-Sectional and Longitudinal Assessment of Structural Brain Alterations in Melancholic Depression , 2011, Biological Psychiatry.
[5] W. Klein,et al. Amyloid-β Triggers the Release of Neuronal Hexokinase 1 from Mitochondria , 2010, PloS one.
[6] György Buzsáki,et al. Predominant Enhancement of Glucose Uptake in Astrocytes versus Neurons during Activation of the Somatosensory Cortex , 2010, The Journal of Neuroscience.
[7] S. Pizzo,et al. Antibodies against the voltage-dependent anion channel (VDAC) and its protective ligand hexokinase-I in children with autism , 2010, Journal of Neuroimmunology.
[8] J. Quevedo,et al. Effects of mood stabilizers on mitochondrial respiratory chain activity in brain of rats treated with d-amphetamine. , 2010, Journal of psychiatric research.
[9] M. Maj,et al. Bipolar Disorder: Clinical and Neurobiological Foundations , 2010 .
[10] M. Berk,et al. Mitochondrial Dysfunction and Oxidative Stress , 2010 .
[11] Anne E Carpenter,et al. Abnormalities in mitochondrial structure in cells from patients with bipolar disorder. , 2010, The American journal of pathology.
[12] Ann K. Shinn,et al. Default mode network abnormalities in bipolar disorder and schizophrenia , 2010, Psychiatry Research: Neuroimaging.
[13] H. Manji,et al. Altered levels of extracellular signal-regulated kinase signaling proteins in postmortem frontal cortex of individuals with mood disorders and schizophrenia. , 2010, Journal of affective disorders.
[14] J. Lieberman,et al. Brain volumes in psychotic youth with schizophrenia and mood disorders. , 2010, Journal of psychiatry & neuroscience : JPN.
[15] R. Myers,et al. Mitochondrial Variants in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder , 2009, PloS one.
[16] R. Conley,et al. Elevated Cerebrospinal Fluid Lactate Concentrations in Patients with Bipolar Disorder and Schizophrenia: Implications for the Mitochondrial Dysfunction Hypothesis , 2009, Biological Psychiatry.
[17] R. Gullapalli,et al. Relationship of cerebrospinal fluid glucose metabolites to MRI deep white matter hyperintensities and treatment resistance in bipolar disorder patients. , 2008, Bipolar disorders.
[18] N. Sims,et al. Isolation of mitochondria from rat brain using Percoll density gradient centrifugation , 2008, Nature Protocols.
[19] Laura L. Vernon,et al. Cognitive correlates of schizophrenia signs and symptoms: II. Emotional disturbances , 2008, Psychiatry Research.
[20] T. Hansen,et al. The estrogen hypothesis of Schizophrenia implicates glucose metabolism: Association study in three independent samples , 2008, BMC Medical Genetics.
[21] C. Broeckhoven,et al. Chromosome 10q harbors a susceptibility locus for bipolar disorder in Ashkenazi Jewish families , 2008, Molecular Psychiatry.
[22] P. Fernyhough,et al. Blockade of hexokinase activity and binding to mitochondria inhibits neurite outgrowth in cultured adult rat sensory neurons , 2008, Neuroscience Letters.
[23] P. Mehta,et al. Intranasal insulin improves cognition and modulates β-amyloid in early AD , 2008, Neurology.
[24] H. Manji,et al. Mitochondrially Mediated Plasticity in the Pathophysiology and Treatment of Bipolar Disorder , 2008, Neuropsychopharmacology.
[25] R. Myers,et al. Mitochondrial involvement in psychiatric disorders , 2008, Annals of medicine.
[26] Jaskaran Singh,et al. Regional Cerebral Glucose Metabolic Abnormalities in Bipolar II Depression , 2007, Biological Psychiatry.
[27] O. Mors,et al. A genome‐wide linkage search for bipolar disorder susceptibility loci in a large and complex pedigree from the eastern part of Cuba , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[28] C. Sabatti,et al. Convergent linkage evidence from two Latin-American population isolates supports the presence of a susceptibility locus for bipolar disorder in 5q31-34. , 2006, Human molecular genetics.
[29] P. van Eerdewegh,et al. Genome scan of Han Chinese schizophrenia families from Taiwan: confirmation of linkage to 10q22.3. , 2006, The American journal of psychiatry.
[30] N. Hay,et al. Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt , 2006, Oncogene.
[31] Elaine Holmes,et al. Metabolic Profiling of CSF: Evidence That Early Intervention May Impact on Disease Progression and Outcome in Schizophrenia , 2006, PLoS medicine.
[32] R. Myers,et al. Mitochondrial-related gene expression changes are sensitive to agonal-pH state: implications for brain disorders , 2006, Molecular Psychiatry.
[33] D. Butterfield,et al. Adriamycin-induced, TNF-α-mediated central nervous system toxicity , 2006, Neurobiology of Disease.
[34] Jun-Feng Wang,et al. Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder. , 2006, Journal of psychiatry & neuroscience : JPN.
[35] V. Haroutunian,et al. Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction , 2006, Schizophrenia Research.
[36] Gary Christopher,et al. The impact of clinical depression on working memory , 2005, Cognitive neuropsychiatry.
[37] A. Schapira,et al. Isolation of transcriptomal changes attributable to LHON mutations and the cybridization process. , 2005, Brain : a journal of neurology.
[38] P. Hauser,et al. Relationship of white matter hyperintensities to cerebrospinal fluid glucose polyol pathway metabolites-a pilot study in treatment-resistant affective disorder patients. , 2005, Journal of affective disorders.
[39] N. Hay,et al. Mitochondrial Hexokinases: Guardians of the Mitochondria , 2005, Cell cycle.
[40] A. Verkhratsky,et al. Insulin enhances mitochondrial inner membrane potential and increases ATP levels through phosphoinositide 3-kinase in adult sensory neurons , 2005, Molecular and Cellular Neuroscience.
[41] Kazuya Iwamoto,et al. Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis. , 2005, Human molecular genetics.
[42] C. Thompson,et al. Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak. , 2004, Molecular cell.
[43] R. Moreno-Sánchez,et al. Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense , 2004, Journal of Biological Chemistry.
[44] E T Bullmore,et al. Reduced volume of parietal and frontal association areas in patients with schizophrenia characterized by passivity delusions , 2004, Psychological Medicine.
[45] J. McGrath,et al. Genomewide linkage scan for bipolar-disorder susceptibility loci among Ashkenazi Jewish families. , 2004, American journal of human genetics.
[46] R. Yolken,et al. Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress , 2004, Molecular Psychiatry.
[47] Ming T Tsuang,et al. Evidence for linkage between regulatory enzymes in glycolysis and schizophrenia in a multiplex sample , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[48] M. Phelps,et al. Acute changes in regional cerebral (18)F-FDG kinetics in patients with traumatic brain injury. , 2004, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[49] In Kyoon Lyoo,et al. Brain metabolic alterations in medication-free patients with bipolar disorder. , 2004, Archives of general psychiatry.
[50] P. Hauser,et al. Post-mortem evidence from human brain tissue of disturbed glucose metabolism in mood and psychotic disorders , 2004, Molecular Psychiatry.
[51] M. Erb,et al. Parietal somatosensory association cortex mediates affective blindsight , 2004, Nature Neuroscience.
[52] Huda Akil,et al. Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditions. , 2004, Human molecular genetics.
[53] Stephan Heckers,et al. Molecular evidence for mitochondrial dysfunction in bipolar disorder. , 2004, Archives of general psychiatry.
[54] N. Freimer,et al. Genetic mapping using haplotype and model‐free linkage analysis supports previous evidence for a locus predisposing to severe bipolar disorder at 5q31‐33 , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.
[55] M. Daly,et al. Genome-wide scan in Portuguese Island families identifies 5q31–5q35 as a susceptibility locus for schizophrenia and psychosis , 2004, Molecular Psychiatry.
[56] N. Kato,et al. Reduced intracellular pH in the basal ganglia and whole brain measured by 31P‐MRS in bipolar disorder , 2004, Psychiatry and clinical neurosciences.
[57] Jalal A Al-jamal. Effect of different thyroid states on mitochondrial porin synthesis and hexokinase activity in developing rabbit brain. , 2004, Journal of biochemistry.
[58] John Eric Wilson. Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function , 2003, Journal of Experimental Biology.
[59] Natalia Ojeda,et al. Functional neuroanatomy of sustained attention in schizophrenia: Contribution of parietal cortices , 2002, Human brain mapping.
[60] E. Kandel,et al. Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase. , 2001, Genes & development.
[61] A. Damasio,et al. Subcortical and cortical brain activity during the feeling of self-generated emotions , 2000, Nature Neuroscience.
[62] J B Poline,et al. Working memory control in patients with schizophrenia: a PET study during a random number generation task. , 2000, The American journal of psychiatry.
[63] N. Kato,et al. Mitochondrial dysfunction in bipolar disorder. , 2000, Bipolar disorders.
[64] F. Mechler,et al. Cerebral blood flow and glucose metabolism in mitochondrial disorders , 2000, Neurology.
[65] R. Yolken,et al. The Stanley Foundation brain collection and Neuropathology Consortium , 2000, Schizophrenia Research.
[66] P. Hauser,et al. Elevated sorbitol concentration in the cerebrospinal fluid of patients with mood disorders , 2000, Psychoneuroendocrinology.
[67] N. Kato,et al. Association of bipolar disorder with the 5178 polymorphism in mitochondrial DNA. , 2000, American journal of medical genetics.
[68] R. Roberts,et al. Mitochondrial pathology in human schizophrenic striatum: a postmortem ultrastructural study , 1999 .
[69] Edward E. Smith,et al. The Role of Parietal Cortex in Verbal Working Memory , 1998, The Journal of Neuroscience.
[70] F. McMahon,et al. Increased levels of a mitochondrial DNA deletion in the brain of patients with bipolar disorder , 1997, Biological Psychiatry.
[71] B. Dutrillaux,et al. Intracellular pH governs the subcellular distribution of hexokinase in a glioma cell line. , 1996, The Biochemical journal.
[72] J. Wilson,et al. Application of a double isotopic labeling method to a study of the interaction of mitochondrially bound rat brain hexokinase with intramitochondrial compartments of ATP generated by oxidative phosphorylation. , 1995, Archives of biochemistry and biophysics.
[73] B. Dutrillaux,et al. Mitochondria‐bound hexokinase as target for therapy of malignant gliomas , 1995, International journal of cancer.
[74] P. Magistretti,et al. Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[75] André Luxen,et al. Frontal and parietal metabolic disturbances in unipolar depression , 1994, Biological Psychiatry.
[76] M. Hayden,et al. Somatic and gonadal mosaicism of the Huntington disease gene CAG repeat in brain and sperm , 1994, Nature Genetics.
[77] N. Arnheim,et al. Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain , 1992, Nature Genetics.
[78] John Eric Wilson,et al. Coordinated regulation of cerebral glycolytic and oxidative metabolism, mediated by mitochondrially bound hexokinase dependent on intramitochondrially generated ATP. , 1992, Archives of biochemistry and biophysics.
[79] R. Lynch,et al. Modulation of hexokinase association with mitochondria analyzed with quantitative three-dimensional confocal microscopy , 1991, The Journal of cell biology.
[80] C. Nahmias,et al. Increased frontal and reduced parietal glucose metabolism in acute untreated schizophrenia , 1989, Psychiatry Research.
[81] I. Silver,et al. ATP and Brain Function , 1989, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[82] S. Ohno,et al. Three subtypes of chronic schizophrenia identified using 11C-glucose positron emission tomography , 1987, Psychiatry Research.
[83] John Eric Wilson,et al. Relative Levels of Hexokinase in Isolated Neuronal, Astrocytic, and Oligodendroglial Fractions from Rat Brain , 1983, Journal of neurochemistry.
[84] H. Jörnvall,et al. Enzyme relationships in a sorbitol pathway that bypasses glycolysis and pentose phosphates in glucose metabolism. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[85] N. Baquer,et al. Hexokinase isoenzymes in diabetes , 1980, Journal of Biosciences.
[86] J J Bartko,et al. Signs and symptoms as predictors of outcome: a report from the International Pilot Study of Schizophrenia. , 1978, The American journal of psychiatry.
[87] R. Berger,et al. Development of mitochondrial energy metabolism in rat brain. , 1977, The Biochemical journal.
[88] H. Knull,et al. Insulin effects on brain energy metabolism and the related hexokinase distribution. , 1974, The Journal of biological chemistry.
[89] K. Gabbay,et al. Sorbitol Pathway: Presence in Nerve and Cord with Substrate Accumulation in Diabetes , 1966, Science.
[90] A. Sols,et al. The association of hexokinase with particulate fractions of brain and other tissue homogenates. , 1953, The Journal of biological chemistry.
[91] Jan Hutny,et al. Further studies on the role of phospholipids in determining the characteristics of mitochondrial binding sites for type I hexokinase. , 2000, Acta biochimica Polonica.