Liposomes for specific depletion of macrophages from organs and tissues.

[1]  N. Van Rooijen,et al.  Subpopulations of Mouse Blood Monocytes Differ in Maturation Stage and Inflammatory Response1 , 2004, The Journal of Immunology.

[2]  N. Rooijen,et al.  Microglia Promote the Death of Developing Purkinje Cells , 2004, Neuron.

[3]  N. Rooijen,et al.  Macrophage depletion in the rat after intraperitoneal administration of liposome-encapsulated clodronate: Depletion kinetics and accelerated repopulation of peritoneal and omental macrophages by administration of freund's adjuvant , 1995, Cell and Tissue Research.

[4]  N. Rooijen Extracellular and intracellular action of clodronate in osteolytic bone diseases? A hypothesis , 1993, Calcified Tissue International.

[5]  N. Rooijen,et al.  Depletion and repopulation of macrophages in spleen and liver of rat after intravenous treatment with liposome-encapsulated dichloromethylene diphosphonate , 1990, Cell and Tissue Research.

[6]  N. Rooijen,et al.  Elimination of phagocytic cells in the spleen after intravenous injection of liposome-encapsulated dichloromethylene diphosphonate , 1984, Cell and Tissue Research.

[7]  P. Marrack,et al.  Liposomal clodronate as a novel agent for treating autoimmune hemolytic anemia in a mouse model. , 2003, Blood.

[8]  N. Rooijen,et al.  Clodronate liposomes: perspectives in research and therapeutics. , 2002 .

[9]  P. H. Goede,et al.  A method for the selective depletion of perivascular and meningeal macrophages in the central nervous system , 2001, Journal of Neuroimmunology.

[10]  T. Papadopoulos,et al.  Importance of Kupffer cells for T-cell-dependent liver injury in mice. , 2000, The American journal of pathology.

[11]  M. Isturiz,et al.  Treatment with liposome-encapsulated clodronate as a new strategic approach in the management of immune thrombocytopenic purpura in a mouse model. , 2000, Blood.

[12]  J. Beijnen,et al.  Synovial macrophage depletion with clodronate-containing liposomes in rheumatoid arthritis. , 2000, Arthritis and rheumatism.

[13]  H. Fleisch Bisphosphonates in Bone Disease: From the Laboratory to the Patient , 2000 .

[14]  N. Van Rooijen,et al.  Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice. , 1998, Journal of immunology.

[15]  D. Klatzmann,et al.  Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover. , 1998, Journal of immunology.

[16]  N. Van Rooijen,et al.  Elimination, blocking, and activation of macrophages: three of a kind? , 1997, Journal of leukocyte biology.

[17]  I. Huitinga,et al.  A novel bone marrow frozen section assay for studying hematopoietic interactions in situ: the role of stromal bone marrow macrophages in erythroblast binding. , 1996, Journal of cell science.

[18]  T. K. van den Berg,et al.  Apoptosis of macrophages induced by liposome-mediated intracellular delivery of clodronate and propamidine. , 1996, Journal of immunological methods.

[19]  N. Van Rooijen,et al.  Kupffer cell depletion by liposome‐delivered drugs: Comparative activity of intracellular clodronate, propamidine, and ethylenediaminetetraacetic acid , 1996, Hepatology.

[20]  N. Van Rooijen,et al.  Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. , 1994, Journal of immunological methods.

[21]  N. Van Rooijen,et al.  Effect of liposome size on the circulation time and intraorgan distribution of amphipathic poly(ethylene glycol)-containing liposomes. , 1994, Biochimica et biophysica acta.

[22]  W. B. van den Berg,et al.  In vivo role of phagocytic synovial lining cells in onset of experimental arthritis. , 1993, The American journal of pathology.

[23]  N. Van Rooijen,et al.  Liposome-mediated macrophage depletion: an experimental approach to study the role of testicular macrophages in the rat. , 1993, The Journal of endocrinology.

[24]  N. Van Rooijen,et al.  Monoclonal antibody mediated targeting of enzymes. A comparative study using the mouse spleen as a model system. , 1992, Journal of immunological methods.

[25]  N. Van Rooijen,et al.  A new method for removal of mononuclear phagocytes from heterogeneous cell populations in vitro, using the liposome-mediated macrophage 'suicide' technique. , 1990, Journal of immunological methods.

[26]  B. Uitdehaag,et al.  Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages , 1990, The Journal of experimental medicine.

[27]  N. Rooijen,et al.  Repopulation of Macrophages in Popliteal Lymph Nodes of Mice After Liposome‐Mediated Depletion , 1990, Journal of leukocyte biology.

[28]  N. Rooijen The liposome-mediated macrophage ‘suicide’ technique , 1989 .

[29]  N. Van Rooijen,et al.  Alveolar macrophage elimination in vivo is associated with an increase in pulmonary immune response in mice , 1989, The Journal of experimental medicine.

[30]  N. Rooijen,et al.  Macrophage Subset Repopulation in the Spleen: Differential Kinetics After Liposome‐Mediated Elimination , 1989, Journal of leukocyte biology.