A safe non-toxic Brucella abortus ghosts induce immune responses and confer protection in BALB/c mice.

[1]  Hui Zhang,et al.  Deletion of the transcriptional regulator GntR down regulated the expression of Genes Related to Virulence and Conferred Protection against Wild‐Type Brucella Challenge in BALB/c Mice , 2017, Molecular immunology.

[2]  Han-Oh Park,et al.  A Salmonella typhimurium ghost vaccine induces cytokine expression in vitro and immune responses in vivo and protects rats against homologous and heterologous challenges , 2017, PloS one.

[3]  Xinglong Wang,et al.  A safe and molecular-tagged Brucella canis ghosts confers protection against virulent challenge in mice. , 2017, Veterinary microbiology.

[4]  G. Tadesse.  Correction: Brucellosis Seropositivity in Animals and Humans in Ethiopia: A Meta-analysis , 2016, PLoS neglected tropical diseases.

[5]  D. Pascual,et al.  Brucellosis vaccines for livestock. , 2016, Veterinary immunology and immunopathology.

[6]  T. Hahn,et al.  Booster vaccination with safe, modified, live-attenuated mutants of Brucella abortus strain RB51 vaccine confers protective immunity against virulent strains of B. abortus and Brucella canis in BALB/c mice. , 2015, Microbiology.

[7]  W. Zhou,et al.  Immune responses and protection induced by Brucella suis S2 bacterial ghosts in mice. , 2015, Veterinary immunology and immunopathology.

[8]  A. Cloeckaert,et al.  The new strains Brucella inopinata BO1 and Brucella species 83-210 behave biologically like classic infectious Brucella species and cause death in murine models of infection. , 2014, The Journal of infectious diseases.

[9]  Chuangfu Chen,et al.  Brucella melitensis 16MΔhfq attenuation confers protection against wild‐type challenge in BALB/c mice , 2013, Microbiology and immunology.

[10]  M. Doğanay,et al.  Brucella as a potential agent of bioterrorism. , 2013, Recent patents on anti-infective drug discovery.

[11]  R. Bhatnagar,et al.  Intradermal immunization with outer membrane protein 25 protects Balb/c mice from virulent B. abortus 544. , 2012, Molecular immunology.

[12]  X. Ji,et al.  Mice vaccinated with enteropathogenic Escherichia coli ghosts show significant protection against lethal challenges , 2012, Letters in applied microbiology.

[13]  A. Atrasheuskaya,et al.  Rectal single dose immunization of mice with Escherichia coli O157:H7 bacterial ghosts induces efficient humoral and cellular immune responses and protects against the lethal heterologous challenge , 2012, Microbial biotechnology.

[14]  Yufei Wang,et al.  The 16MΔvjbR as an ideal live attenuated vaccine candidate for differentiation between Brucella vaccination and infection. , 2011, Veterinary microbiology.

[15]  R. Ashman,et al.  Immunisation with the glycolytic enzyme enolase confers effective protection against Candida albicans infection in mice. , 2011, Vaccine.

[16]  T. Ficht.  Brucella taxonomy and evolution. , 2010, Future microbiology.

[17]  H. Liu,et al.  Intragastric immunization of mice with enterohemorrhagic Escherichia coli O157:H7 bacterial ghosts reduces mortality and shedding and induces a Th2-type dominated mixed immune response. , 2010, Canadian journal of microbiology.

[18]  G. Vergnaud,et al.  Brucella inopinata sp. nov., isolated from a breast implant infection. , 2010, International journal of systematic and evolutionary microbiology.

[19]  W. Chu,et al.  Effect of oral immunization with Aeromonas hydrophila ghosts on protection against experimental fish infection , 2010, Letters in applied microbiology.

[20]  B. Sánchez,et al.  Evaluation of vaccination with Brucella abortus S19 vaccine in cattle naturally infected with brucellosis in productive systems found in the Mexican tropic. , 2009 .

[21]  Xuepeng Wang,et al.  Mice orally vaccinated with Edwardsiella tarda ghosts are significantly protected against infection. , 2009, Vaccine.

[22]  Eun Hye Lee,et al.  Generation of Vibrio anguillarum Ghost by Coexpression of PhiX 174 Lysis E gene and Staphylococcal Nuclease A Gene , 2009, Molecular biotechnology.

[23]  Eun Hye Lee,et al.  Generation of safety enhanced Edwardsiella tarda ghost vaccine. , 2008, Diseases of aquatic organisms.

[24]  Z. Hubálek,et al.  Brucella microti sp. nov., isolated from the common vole Microtus arvalis. , 2008, International journal of systematic and evolutionary microbiology.

[25]  J. Godfroid,et al.  Brucella ceti sp. nov. and Brucella pinnipedialis sp. nov. for Brucella strains with cetaceans and seals as their preferred hosts. , 2007, International journal of systematic and evolutionary microbiology.

[26]  R. Gilman,et al.  Human brucellosis. , 2007, The Lancet. Infectious diseases.

[27]  I. Moriyón,et al.  Increases of efficacy as vaccine against Brucella abortus infection in mice by simultaneous inoculation with avirulent smooth bvrS/bvrR and rough wbkA mutants. , 2006, Vaccine.

[28]  N. Casali,et al.  Regulation of the Mycobacterium tuberculosis mce1 Operon , 2006, Journal of bacteriology.

[29]  C. Lambert,et al.  Systematic Targeted Mutagenesis of Brucella melitensis 16M Reveals a Major Role for GntR Regulators in the Control ofVirulence , 2005, Infection and Immunity.

[30]  G. Riccardi,et al.  Protective Properties of Rifampin-Resistant Rough Mutants of Brucella melitensis , 2005, Infection and Immunity.

[31]  C. Woods,et al.  Adverse events in humans associated with accidental exposure to the livestock brucellosis vaccine RB51. , 2004, Vaccine.

[32]  W. Lubitz,et al.  Dynamics of PhiX174 protein E-mediated lysis of Escherichia coli , 2004, Archives of Microbiology.

[33]  E. Moreno,et al.  Rough vaccines in animal brucellosis: structural and genetic basis and present status. , 2004, Veterinary research.

[34]  R. Ugalde,et al.  Evaluation of Brucella abortus Phosphoglucomutase (pgm) Mutant as a New Live Rough-Phenotype Vaccine , 2003, Infection and Immunity.

[35]  R. Berkelman.  Human illness associated with use of veterinary vaccines. , 2003, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[36]  F. Eko,et al.  Recombinant Vibrio cholerae ghosts as a delivery vehicle for vaccinating against Chlamydia trachomatis. , 2003, Vaccine.

[37]  A. Hensel,et al.  Bacterial ghosts as vaccine candidates for veterinary applications. , 2002, Journal of controlled release : official journal of the Controlled Release Society.

[38]  D. O’Callaghan,et al.  Brucellosis: a worldwide zoonosis. , 2001, Current opinion in microbiology.

[39]  D. Scott,et al.  Immunity and protection against Brucella abortus. , 2001, Microbes and infection.

[40]  Z. Bercovich.  The use of skin delayed‐type hypersensitivity as an adjunct test to diagnose brucellosis in cattle: A review , 2000, The Veterinary quarterly.

[41]  J. Letesson,et al.  Quantitative assessment by flow cytometry of T-lymphocytes producing antigen-specific gamma-interferon in Brucella immune cattle. , 1998, Veterinary immunology and immunopathology.

[42]  S. Hagius,et al.  Safety of Brucella abortus Strain RB51 in Bison , 1998, Journal of wildlife diseases.

[43]  R. Maizels,et al.  Th1-Th2: reliable paradigm or dangerous dogma? , 1997, Immunology today.

[44]  P. Thompson,et al.  Brucella species infection in North Sea seal and cetacean populations , 1996, Veterinary Record.

[45]  S. Olsen,et al.  Antibody responses to Brucella abortus 2308 in cattle vaccinated with B. abortus RB51 , 1996, Infection and immunity.

[46]  G. Schurig,et al.  Electroporation of a suicide plasmid bearing a transposon into Brucella abortus. , 1990, Microbial pathogenesis.

[47]  L. Araya,et al.  Comparative protection of mice against virulent and attenuated strains of Brucella abortus by passive transfer of immune T cells or serum , 1990, Infection and immunity.

[48]  H. Erdem.  Brucellosis , 1954, The Lancet.