Dysregulated immune system networks in war veterans with PTSD is an outcome of altered miRNA expression and DNA methylation

[1]  J. Ginsberg,et al.  Evidence for Epigenetic Regulation of Pro-Inflammatory Cytokines, Interleukin-12 and Interferon Gamma, in Peripheral Blood Mononuclear Cells from PTSD Patients , 2016, Journal of Neuroimmune Pharmacology.

[2]  Tanja Jovanovic,et al.  Diagnostic Biomarkers for Posttraumatic Stress Disorder: Promising Horizons from Translational Neuroscience Research , 2015, Biological Psychiatry.

[3]  N. Greenberg,et al.  Latest developments in post-traumatic stress disorder: diagnosis and treatment. , 2015, British medical bulletin.

[4]  T. Neylan,et al.  Elevated Risk for Autoimmune Disorders in Iraq and Afghanistan Veterans with Posttraumatic Stress Disorder , 2015, Biological Psychiatry.

[5]  D. Schübeler Function and information content of DNA methylation , 2015, Nature.

[6]  Michael S. Breen,et al.  Gene Networks Specific for Innate Immunity Define Post-Traumatic Stress Disorder , 2015, Molecular Psychiatry.

[7]  R. Alon,et al.  Leukocyte migration into inflamed tissues. , 2014, Immunity.

[8]  Daehyun Baek,et al.  mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues. , 2014, Molecular cell.

[9]  B. Strahl,et al.  Interpreting the language of histone and DNA modifications. , 2014, Biochimica et biophysica acta.

[10]  C. M. Eischen,et al.  Cell survival is dicey without Dicer , 2014, Molecular & cellular oncology.

[11]  J. Ginsberg,et al.  Dysregulation in microRNA Expression Is Associated with Alterations in Immune Functions in Combat Veterans with Post-Traumatic Stress Disorder , 2014, PloS one.

[12]  R. Germain,et al.  The multiple faces of leukocyte interstitial migration , 2014, Seminars in Immunopathology.

[13]  W. Krzyzosiak,et al.  The panorama of miRNA-mediated mechanisms in mammalian cells , 2014, Cellular and Molecular Life Sciences.

[14]  Graham M Lord,et al.  T-bet: a bridge between innate and adaptive immunity , 2013, Nature Reviews Immunology.

[15]  P. Casali,et al.  Epigenetics of the antibody response. , 2013, Trends in immunology.

[16]  Louisa Flintoft,et al.  Non-coding RNA: Structure and function for lncRNAs , 2013, Nature Reviews Genetics.

[17]  K. Mark Ansel,et al.  MicroRNA-mediated regulation of T helper cell differentiation and plasticity , 2013, Nature Reviews Immunology.

[18]  Louisa Flintoft,et al.  Evolution: Speciation meets microbiomes , 2013, Nature Reviews Genetics.

[19]  M. Muers Gene expression: Disentangling DNA methylation , 2013, Nature Reviews Genetics.

[20]  B. Suarez-Alvarez,et al.  Epigenetic modulation of the immune function , 2013, Epigenetics.

[21]  J. Bluestone,et al.  MicroRNA regulation of T‐cell differentiation and function , 2013, Immunological reviews.

[22]  S. Abrignani,et al.  Role of microRNAs and long‐non‐coding RNAs in CD4+ T‐cell differentiation , 2013, Immunological reviews.

[23]  Cole Trapnell,et al.  TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions , 2013, Genome Biology.

[24]  J. Gill,et al.  Epigenetic Mechanisms Shape the Biological Response to Trauma and Risk for PTSD: A Critical Review , 2013, Nursing research and practice.

[25]  T. Elbert,et al.  Posttraumatic stress disorder is associated with an enhanced spontaneous production of pro-inflammatory cytokines by peripheral blood mononuclear cells , 2013, BMC Psychiatry.

[26]  Anushya Muruganujan,et al.  PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees , 2012, Nucleic Acids Res..

[27]  K. Oestreich,et al.  Transcriptional mechanisms that regulate T helper 1 cell differentiation. , 2012, Current opinion in immunology.

[28]  G. Newton,et al.  Emerging mechanisms of neutrophil recruitment across endothelium. , 2011, Trends in immunology.

[29]  A. Luster,et al.  Neutrophils cascading their way to inflammation. , 2011, Trends in immunology.

[30]  L. Glimcher,et al.  T-bet in disease , 2011, Nature Immunology.

[31]  S. Galea,et al.  Epigenetic and immune function profiles associated with posttraumatic stress disorder , 2010, Proceedings of the National Academy of Sciences.

[32]  Cole Trapnell,et al.  Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.

[33]  Terry L. Schell,et al.  Disparate prevalence estimates of PTSD among service members who served in Iraq and Afghanistan: possible explanations. , 2010, Journal of traumatic stress.

[34]  J. Gill,et al.  PTSD is associated with an excess of inflammatory immune activities. , 2009, Perspectives in psychiatric care.

[35]  Steven J. M. Jones,et al.  Circos: an information aesthetic for comparative genomics. , 2009, Genome research.

[36]  E. Shevach Mechanisms of foxp3+ T regulatory cell-mediated suppression. , 2009, Immunity.

[37]  Brad T. Sherman,et al.  Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists , 2008, Nucleic acids research.

[38]  Jay K Kolls,et al.  The Biological Functions of T Helper 17 Cell Effector Cytokines in Inflammation , 2022 .

[39]  J. O’Shea,et al.  Cytokine signaling modules in inflammatory responses. , 2008, Immunity.

[40]  H. Lodish,et al.  Micromanagement of the immune system by microRNAs , 2008, Nature Reviews Immunology.

[41]  Olga V. Demler,et al.  Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. , 2005, Archives of general psychiatry.

[42]  C. Burge,et al.  Conserved Seed Pairing, Often Flanked by Adenosines, Indicates that Thousands of Human Genes are MicroRNA Targets , 2005, Cell.

[43]  Joseph A Boscarino,et al.  Posttraumatic Stress Disorder and Physical Illness: Results from Clinical and Epidemiologic Studies , 2004, Annals of the New York Academy of Sciences.

[44]  V. Ambros The functions of animal microRNAs , 2004, Nature.

[45]  Lin He,et al.  MicroRNAs: small RNAs with a big role in gene regulation , 2004, Nature Reviews Genetics.

[46]  D. Bartel MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[47]  Steffen Jung,et al.  Blood monocytes consist of two principal subsets with distinct migratory properties. , 2003, Immunity.

[48]  Yusuke Nakamura,et al.  Identification of AXUD1, a novel human gene induced by AXIN1 and its reduced expression in human carcinomas of the lung, liver, colon and kidney , 2001, Oncogene.

[49]  A. Zlotnik,et al.  Chemokines: a new classification system and their role in immunity. , 2000, Immunity.

[50]  M. Perretti,et al.  Lipocortin 1 and chemokine modulation of granulocyte and monocyte accumulation in experimental inflammation. , 1998, General pharmacology.

[51]  J. Westwick,et al.  Chemokines and T lymphocytes: more than an attraction. , 1998, Immunity.

[52]  E. Blanchard,et al.  Psychometric properties of the PTSD Checklist (PCL). , 1996, Behaviour research and therapy.

[53]  G. Trinchieri,et al.  Immune interferon: a pleiotropic lymphokine with multiple effects. , 1985, Immunology today.

[54]  M. Nagarkatti,et al.  Dysregulation in microRNA expression in peripheral blood mononuclear cells of sepsis patients is associated with immunopathology. , 2015, Cytokine.

[55]  G. Fan,et al.  DNA Methylation and Its Basic Function , 2013, Neuropsychopharmacology.

[56]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[57]  P. Hordijk Endothelial signaling in leukocyte transmigration , 2007, Cell Biochemistry and Biophysics.

[58]  J. Talbott Prevalence, Severity, and Comorbidity of 12-Month DSM-IV Disorders in the National Comorbidity Survey Replication , 2006 .

[59]  Eric J Kunkel,et al.  Chemokines and the tissue-specific migration of lymphocytes. , 2002, Immunity.

[60]  J. Cyster,et al.  CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity. , 2002, Immunity.

[61]  H. Schellekens,et al.  Cytokines and the immune response , 1996, Biotherapy.

[62]  D. Charney,et al.  The development of a Clinician-Administered PTSD Scale , 1995, Journal of traumatic stress.