Aflatoxin M1 Contamination in Pasteurized Milk in Mashhad, Iran

The aim of this study was to evaluate aflatoxin M 1 (AFM 1 ) contamination in pasteurized milk samples in Mashhad, Iran. One hundred and ten milk samples from different supermarkets were collected during three months in spring and investigated by Enzyme Linked Immuno Sorbent Assay (ELISA). AFM 1 was found in 100% of the milk samples. About 5.4% of the samples contained AFM 1 greater than the maximum tolerance limit (0.05 μg/l) accepted by European Union. There was not a significant difference among the mean value of AFM 1 in three months.

[1]  D. Wagner,et al.  Aflatoxin Residues in Milk of Dairy Cows after Ingestion of Naturally Contaminated Grain. , 1986, Journal of food protection.

[2]  S. Girotti,et al.  Aflatoxin M1 in milk: Reliability of the immunoenzymatic assay , 2007 .

[3]  F. Chu.  Mycotoxins: food contamination, mechanism, carcinogenic potential and preventive measures. , 1991, Mutation research.

[4]  F. Galvano,et al.  Detoxification methods of aflatoxins. A review , 1995 .

[5]  Timothy D Phillips,et al.  Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions. , 2004, The American journal of clinical nutrition.

[6]  J. Blanco,et al.  Presence of aflatoxin M1 in commercial ultra-high-temperature-treated milk , 1988, Applied and environmental microbiology.

[7]  A. Kamkar,et al.  A study on the occurrence of aflatoxin M1 in raw milk produced in Sarab city of Iran , 2005 .

[8]  Ismail Y.S. Rustom.  Aflatoxin in food and feed: occurrence, legislation and inactivation by physical methods , 1997 .

[9]  Aldo Roda,et al.  Development and validation of an ultrasensitive chemiluminescent enzyme immunoassay for aflatoxin M1 in milk. , 2005, Journal of agricultural and food chemistry.

[10]  C. Polan,et al.  Consumption and fate of aflatoxin B1 by lactating cows. , 1974, Journal of agricultural and food chemistry.

[11]  Y. Soini,et al.  Reactive oxygen species and antioxidant mechanisms in human tissues and their relation to malignancies , 2007, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[12]  Amos J. Peaslee,et al.  German Federal Republic , 1974 .

[13]  Behrooz Astaneh,et al.  Aflatoxin M1 contamination in pasteurized milk in Shiraz (south of Iran) , 2006 .

[14]  L. Bullerman,et al.  Significance of Mycotoxins to Food Safety and Human Health 1, 2. , 1979, Journal of food protection.

[15]  A J Hall,et al.  Dietary aflatoxin exposure and impaired growth in young children from Benin and Togo: cross sectional study , 2002, BMJ : British Medical Journal.

[16]  Douglas L. Park,et al.  Effect of processing on aflatoxin. , 2002, Advances in experimental medicine and biology.

[17]  B. Jannat,et al.  Presence of aflatoxin M1 in milk and infant milk products in Tehran, Iran , 2007 .