论文信息 - Transient Pseudohypoaldosteronism in an infant with urinary tract anomaly

Transient Pseudohypoaldosteronism in an infant with urinary tract anomaly

Transient pseudohypoaldosteronism (TPHA) due to renal tubular unresponsiveness to aldosterone and manifested by hyperkalemia, hyponatremia, metabolic acidosis and marked increase in plasma aldosterone concentration, has been previously identified in infants with obstructive uropathy and urinary tract infection (UTI). 1,2 TPHA can be cured by treatment for the UTI or surgery. 1 We report a case of TPHA caused by urinary tract infection associated with left vesicoureteral reflux.

[1] E. Schoen,et al. Transient pseudohypoaldosteronism with hyponatremia-hyperkalemia in infant urinary tract infection. , 2002, The Journal of urology.

[2] G. Marra,et al. Acute pyelonephritis as a cause of hyponatremia/hyperkalemia in young infants with urinary tract malformations , 1995, The Pediatric infectious disease journal.

[3] A. Vallo,et al. Normokalaemic pseudohypoaldosteronism is present in children with acute pyelonephritis , 1992, Acta paediatrica.

[4] G. Marra,et al. Increased sodium requirement following early postnatal surgical correction of congenital uropathies in infants , 1990, Pediatric Nephrology.

[5] E. Schoen. The foreskin and urinary tract infections. , 1989, The Journal of pediatrics.

[6] G. Marra,et al. Persistent tubular resistance to aldosterone in infants with congenital hydronephrosis corrected neonatally. , 1987, The Journal of pediatrics.

[7] A. Vallo,et al. Transient pseudohypoaldosteronism secondary to obstructive uropathy in infancy. , 1983, The Journal of pediatrics.