Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI3K and microglia in mice
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F. Cunha | R. Casagrande | W. Verri | S. Ferreira | T. Cunha | Ana C Zarpelon | A. C. Zarpelon | S. S. Mizokami | Gabriela F. Pavão-de-Souza | Giovana C. Tedeschi | Joice S. Sanson | Sandra S. Mizokami
[1] F. Cunha,et al. Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice , 2011, Pharmacology Biochemistry and Behavior.
[2] Z. Tanfin,et al. MAPK14 Cooperates with MAPK3/1 to Regulate Endothelin-1-Mediated Prostaglandin Synthase 2 Induction and Survival in Leiomyoma but Not in Normal Myometrial Cells1 , 2011, Biology of reproduction.
[3] A. Newton,et al. Spinal Phosphinositide 3-Kinase–Akt–Mammalian Target of Rapamycin Signaling Cascades in Inflammation-Induced Hyperalgesia , 2011, The Journal of Neuroscience.
[4] R. Burstein,et al. Tumor necrosis factor-α induces sensitization of meningeal nociceptors mediated via local COX and p38 MAP kinase actions , 2011, PAIN®.
[5] A. Light,et al. Peripheral formalin injury induces 2 stages of microglial activation in the spinal cord. , 2010, The journal of pain : official journal of the American Pain Society.
[6] G. Landreth,et al. Genetic Targeting of ERK1 Suggests a Predominant Role for ERK2 in Murine Pain Models , 2010, The Journal of Neuroscience.
[7] D. Tian,et al. Effect of pre-electroacupuncture on p38 and c-Fos expression in the spinal dorsal horn of rats suffering from visceral pain. , 2010, Chinese medical journal.
[8] Yan Yuan,et al. Phosphatidylinositol 3-kinase mediates pain behaviors induced by activation of peripheral ephrinBs/EphBs signaling in mice , 2010, Pharmacology Biochemistry and Behavior.
[9] L. Sorkin,et al. Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior , 2010, PAIN®.
[10] J. Mao,et al. Systemic minocycline differentially influences changes in spinal microglial markers following formalin-induced nociception , 2010, Journal of Neuroimmunology.
[11] R. Ji,et al. Chemokines, neuronal-glial interactions, and central processing of neuropathic pain. , 2010, Pharmacology & therapeutics.
[12] C. Svensson,et al. Role of spinal p38α and β MAPK in inflammatory hyperalgesia and spinal COX-2 expression , 2010, Neuroreport.
[13] D. Cho,et al. IL-18 downregulates collagen production in human dermal fibroblasts via the ERK pathway. , 2010, The Journal of investigative dermatology.
[14] M. Zheng,et al. Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors , 2010, Molecular Pain.
[15] M. Fonseca,et al. Quercetin reduces inflammatory pain: inhibition of oxidative stress and cytokine production. , 2009, Journal of natural products.
[16] T. Stankowich. Behavior , 2009, The Quarterly Review of Biology.
[17] L. Sorkin,et al. MKK3, an upstream activator of p38, contributes to formalin phase 2 and late allodynia in mice , 2009, Neuroscience.
[18] J. Seo,et al. Cytokine production through PKC/p38 signaling pathways, not through JAK/STAT1 pathway, in mast cells stimulated with IFNgamma. , 2009, Cytokine.
[19] Hui-sheng Chen,et al. Differential roles of peripheral mitogen-activated protein kinase signal transduction pathways in bee venom-induced nociception and inflammation in conscious rats. , 2009, The journal of pain : official journal of the American Pain Society.
[20] F. Cunha,et al. Teleantagonism: A pharmacodynamic property of the primary nociceptive neuron , 2008, Proceedings of the National Academy of Sciences.
[21] K. Noguchi,et al. Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury , 2008, The Journal of Neuroscience.
[22] F. Liew,et al. Role of IL-18 in overt pain-like behaviour in mice. , 2008, European journal of pharmacology.
[23] John Grist,et al. Phosphatidylinositol 3-Kinase Is a Key Mediator of Central Sensitization in Painful Inflammatory Conditions , 2008, The Journal of Neuroscience.
[24] F. Liew,et al. IL-33 mediates antigen-induced cutaneous and articular hypernociception in mice , 2008, Proceedings of the National Academy of Sciences.
[25] H. Cao,et al. Evidence for suppression of electroacupuncture on spinal glial activation and behavioral hypersensitivity in a rat model of monoarthritis , 2008, Brain Research Bulletin.
[26] Ji-Tian Xu,et al. Activation of phosphatidylinositol 3-kinase and protein kinase B/Akt in dorsal root ganglia and spinal cord contributes to the neuropathic pain induced by spinal nerve ligation in rats , 2007, Experimental Neurology.
[27] F. Cunha,et al. Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. , 2007, European journal of pharmacology.
[28] M. Bähr,et al. Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation , 2007, Neurobiology of Disease.
[29] L. Duan,et al. Blocking the glial function suppresses subcutaneous formalin-induced nociceptive behavior in the rat , 2007, Neuroscience Research.
[30] F. Cunha,et al. Hypernociceptive role of cytokines and chemokines: targets for analgesic drug development? , 2006, Pharmacology & therapeutics.
[31] L. Duan,et al. The lumbar spinal cord glial cells actively modulate subcutaneous formalin induced hyperalgesia in the rat , 2006, Neuroscience Research.
[32] T. Bártfai,et al. MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[33] Robert W. Gereau,et al. Acute p38-Mediated Modulation of Tetrodotoxin-Resistant Sodium Channels in Mouse Sensory Neurons by Tumor Necrosis Factor-α , 2006, The Journal of Neuroscience.
[34] C. Svensson,et al. Intrathecal minocycline attenuates peripheral inflammation‐induced hyperalgesia by inhibiting p38 MAPK in spinal microglia , 2005, The European journal of neuroscience.
[35] T. Yamashita,et al. c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity. , 2005, Biochemical and biophysical research communications.
[36] S. Ho,et al. Inhibition of p38 mitogen‐activated protein kinase attenuates interleukin‐1β‐induced thermal hyperalgesia and inducible nitric oxide synthase expression in the spinal cord , 2005, Journal of neurochemistry.
[37] S. Maier,et al. Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation , 2005, Pain.
[38] C. Woolf,et al. ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model , 2005, Pain.
[39] Yi Dai,et al. Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats , 2004, The European journal of neuroscience.
[40] R. Ji,et al. Cell Signaling and the Genesis of Neuropathic Pain , 2004, Science's STKE.
[41] D. Clapham,et al. Phosphatidylinositol 3-Kinase Activates ERK in Primary Sensory Neurons and Mediates Inflammatory Heat Hyperalgesia through TRPV1 Sensitization , 2004, The Journal of Neuroscience.
[42] J. Chichorro,et al. Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin‐induced orofacial nociception in rats , 2004, British journal of pharmacology.
[43] N. Calcutt,et al. Activation of p38 mitogen‐activated protein kinase in spinal microglia is a critical link in inflammation‐induced spinal pain processing , 2003, Journal of neurochemistry.
[44] Shokei Kim,et al. Stress and vascular responses: mitogen-activated protein kinases and activator protein-1 as promising therapeutic targets of vascular remodeling. , 2003, Journal of pharmacological sciences.
[45] S. Maier,et al. Spinal Glia and Proinflammatory Cytokines Mediate Mirror-Image Neuropathic Pain in Rats , 2003, The Journal of Neuroscience.
[46] S. Kulkarni,et al. Role of cysteinyl leukotrienes in nociceptive and inflammatory conditions in experimental animals. , 2001, European journal of pharmacology.
[47] F. Cunha,et al. Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice. , 2000, European journal of pharmacology.
[48] J. Vane,et al. Nociception in cyclooxygenase isozyme-deficient mice. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[49] S. Maier,et al. Reversal of spinal cord non-opiate analgesia by conditioned anti-analgesia in the rat , 1997, Pain.
[50] C. Marshall,et al. Tyrosine 763 of the murine granulocyte colony-stimulating factor receptor mediates Ras-dependent activation of the JNK/SAPK mitogen-activated protein kinase pathway , 1997, Molecular and cellular biology.
[51] A. Eschalier,et al. A method to perform direct transcutaneous intrathecal injection in rats. , 1994, Journal of pharmacological and toxicological methods.
[52] J. Joris,et al. Bradykinin is increased during acute and chronic inflammation: Therapeutic implications , 1988, Clinical pharmacology and therapeutics.
[53] S. Ferreira,et al. Central and peripheral antialgesic action of aspirin-like drugs. , 1978, European journal of pharmacology.
[54] D. Dubuisson,et al. The formalin test: A quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats , 1977, Pain.
[55] H. Collier,et al. The abdominal constriction response and its suppression by analgesic drugs in the mouse. , 1968, British journal of pharmacology and chemotherapy.
[56] S. Je,et al. Analgesic acitivity of namoxyrate (2-[4-biphenylyl] butyric acid 2-dimethylaminoethanol salt). , 1967 .
[57] B. Yoburn,et al. Pharmacology, Biochemistry and Behavior , 2012 .
[58] J. Emele,et al. Analgesic acitivity of namoxyrate (2-[4-biphenylyl] butyric acid 2-dimethylaminoethanol salt). , 1967, Archives internationales de pharmacodynamie et de therapie.