ABCA1-mediated Cholesterol Efflux Is Defective in Free Cholesterol-loaded Macrophages
暂无分享,去创建一个
[1] S. Yokoyama,et al. Helical Apolipoproteins Stabilize ATP-binding Cassette Transporter A1 by Protecting It from Thiol Protease-mediated Degradation* , 2002, The Journal of Biological Chemistry.
[2] G. Schmitz,et al. ATP-binding cassette (ABC) transporters in atherosclerosis , 2002, Current atherosclerosis reports.
[3] W. Fung-Leung,et al. Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[4] W. J. Johnson,et al. Effects of Enrichment of Fibroblasts with Unesterified Cholesterol on the Efflux of Cellular Lipids to Apolipoprotein A-I* , 2002, The Journal of Biological Chemistry.
[5] O. Francone,et al. Increased Atherosclerosis in Hyperlipidemic Mice With Inactivation of ABCA1 in Macrophages , 2002, Arteriosclerosis, thrombosis, and vascular biology.
[6] J. Oram,et al. Unsaturated Fatty Acids Inhibit Cholesterol Efflux from Macrophages by Increasing Degradation of ATP-binding Cassette Transporter A1* , 2002, The Journal of Biological Chemistry.
[7] A. Zwinderman,et al. Association between increased arterial-wall thickness and impairment in ABCA1-driven cholesterol efflux: an observational study , 2002, The Lancet.
[8] A. Horwitz,et al. Stably transfected ABCA1 antisense cell line has decreased ABCA1 mRNA and cAMP-induced cholesterol efflux to apolipoprotein AI and HDL. , 2001, Biochimica et biophysica acta.
[9] A. Tall,et al. Acid Sphingomyelinase-deficient Macrophages Have Defective Cholesterol Trafficking and Efflux* , 2001, The Journal of Biological Chemistry.
[10] Carrie M. Welch,et al. Preferential ATP-binding Cassette Transporter A1-mediated Cholesterol Efflux from Late Endosomes/Lysosomes* , 2001, The Journal of Biological Chemistry.
[11] P. M. Yao,et al. Free Cholesterol Loading of Macrophages Is Associated with Widespread Mitochondrial Dysfunction and Activation of the Mitochondrial Apoptosis Pathway* , 2001, The Journal of Biological Chemistry.
[12] E. Ikonen,et al. Mass spectrometric analysis reveals an increase in plasma membrane polyunsaturated phospholipid species upon cellular cholesterol loading. , 2001, Biochemistry.
[13] Y. Ouchi,et al. Foam cell formation containing lipid droplets enriched with free cholesterol by hyperlipidemic serum. , 2001, Journal of lipid research.
[14] M. Hayden,et al. Pivotal role of ABCA1 in reverse cholesterol transport influencing HDL levels and susceptibility to atherosclerosis. , 2001, Journal of lipid research.
[15] A. Kinsara. 2000 Guidelines for Cardiopulmonary Resuscitation Emergency Cardiovascular Care. , 2001, Circulation.
[16] A. Tall,et al. ATP-binding Cassette Transporter A1 (ABCA1) Functions as a Cholesterol Efflux Regulatory Protein* , 2001, The Journal of Biological Chemistry.
[17] R. Lawn,et al. ABCA1. The gatekeeper for eliminating excess tissue cholesterol. , 2001, Journal of lipid research.
[18] H. Rigneault,et al. Specific Docking of Apolipoprotein A-I at the Cell Surface Requires a Functional ABCA1 Transporter* , 2001, The Journal of Biological Chemistry.
[19] Robert V Farese,et al. Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. , 2001, The Journal of clinical investigation.
[20] I. Tabas,et al. Cholesterol and phospholipid metabolism in macrophages. , 2000, Biochimica et biophysica acta.
[21] A. Tall,et al. Tangier disease as a test of the reverse cholesterol transport hypothesis. , 2000, The Journal of clinical investigation.
[22] P. M. Yao,et al. Macrophages deficient in CTP:Phosphocholine cytidylyltransferase-alpha are viable under normal culture conditions but are highly susceptible to free cholesterol-induced death. Molecular genetic evidence that the induction of phosphatidylcholine biosynthesis in free cholesterol-loaded macrophages is , 2000, The Journal of biological chemistry.
[23] R. Lawn,et al. ABCA1 Is the cAMP-inducible Apolipoprotein Receptor That Mediates Cholesterol Secretion from Macrophages* , 2000, The Journal of Biological Chemistry.
[24] C. Fielding,et al. A two-step mechanism for free cholesterol and phospholipid efflux from human vascular cells to apolipoprotein A-1. , 2000, Biochemistry.
[25] R. Virmani,et al. Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death. , 2000, The American journal of pathology.
[26] P. M. Yao,et al. Free Cholesterol Loading of Macrophages Induces Apoptosis Involving the Fas Pathway* , 2000, The Journal of Biological Chemistry.
[27] T. Steck,et al. Cholesterol Movement in Niemann-Pick Type C Cells and in Cells Treated with Amphiphiles* , 2000, The Journal of Biological Chemistry.
[28] Y. Geng,et al. Cytotoxic cholesterol is generated by the hydrolysis of cytoplasmic cholesteryl ester and transported to the plasma membrane. , 1999, Atherosclerosis.
[29] I. Tabas,et al. Macrophage-targeted CTP:phosphocholine cytidylyltransferase (1-314) transgenic mice. , 1999, Biochimica et biophysica acta.
[30] J. Freyssinet,et al. Shed membrane microparticles with procoagulant potential in human atherosclerotic plaques: a role for apoptosis in plaque thrombogenicity. , 1999, Circulation.
[31] W. Pavan,et al. Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene. , 1997, Science.
[32] M. Bennett,et al. Cell death in atherosclerotic plaques , 1996, Current opinion in lipidology.
[33] I. Tabas,et al. Evidence That the Initial Up-regulation of Phosphatidylcholine Biosynthesis in Free Cholesterol-loaded Macrophages Is an Adaptive Response That Prevents Cholesterol-induced Cellular Necrosis , 1996, The Journal of Biological Chemistry.
[34] L. Liscum,et al. Quantitative analysis of hydrophobic amine inhibition of intracellular cholesterol transport. , 1996, Journal of lipid research.
[35] M. Houweling,et al. Stimulation of CTP:Phosphocholine Cytidylyltransferase by Free Cholesterol Loading of Macrophages Involves Signaling through Protein Dephosphorylation (*) , 1995, The Journal of Biological Chemistry.
[36] J. Skepper,et al. Evidence that the death of macrophage foam cells contributes to the lipid core of atheroma. , 1995, Atherosclerosis.
[37] W. J. Johnson,et al. Cell Toxicity Induced by Inhibition of Acyl Coenzyme A:Cholesterol Acyltransferase and Accumulation of Unesterified Cholesterol * , 1995, The Journal of Biological Chemistry.
[38] H. Greten,et al. Selective uptake of low-density lipoprotein-associated cholesteryl esters by human fibroblasts, human HepG2 hepatoma cells and J774 macrophages in culture. , 1995, Biochimica et biophysica acta.
[39] R. Ross,et al. Cell biology of atherosclerosis. , 1995, Annual review of physiology.
[40] I. Tabas,et al. Free cholesterol loading of macrophages stimulates phosphatidylcholine biosynthesis and up-regulation of CTP: phosphocholine cytidylyltransferase. , 1994, The Journal of biological chemistry.
[41] Steven K. Clinton,et al. The role of macrophages in atherogenesis , 1993 .
[42] V. Fuster,et al. The pathogenesis of coronary artery disease and the acute coronary syndromes (2). , 1992, The New England journal of medicine.
[43] M. Bond,et al. Immunohistochemical localization of heat shock protein-70 in normal-appearing and atherosclerotic specimens of human arteries. , 1990, The American journal of pathology.
[44] L. Liscum,et al. The intracellular transport of low density lipoprotein-derived cholesterol is inhibited in Chinese hamster ovary cells cultured with 3-beta-[2-(diethylamino)ethoxy]androst-5-en-17-one. , 1989, The Journal of biological chemistry.
[45] A. Tall,et al. Foam cell-forming J774 macrophages have markedly elevated acyl coenzyme A:cholesterol acyl transferase activity compared with mouse peritoneal macrophages in the presence of low density lipoprotein (LDL) despite similar LDL receptor activity. , 1987, The Journal of clinical investigation.
[46] B Lundberg,et al. Chemical composition and physical state of lipid deposits in atherosclerosis. , 1985, Atherosclerosis.
[47] M. Bond,et al. Physicochemical and histological changes in the arterial wall of nonhuman primates during progression and regression of atherosclerosis. , 1984, The Journal of clinical investigation.
[48] A. Ross,et al. Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035. , 1984, The Journal of biological chemistry.
[49] D. S. Lin,et al. Lipids of human atherosclerotic plaques and xanthomas: clues to the mechanism of plaque progression. , 1983, Journal of lipid research.
[50] H. Brewer,et al. Coronary heart disease prevalence and other clinical features in familial high-density lipoprotein deficiency (Tangier disease). , 1980, Annals of internal medicine.
[51] H. Shio,et al. Characterization of lipid-laden aortic cells from cholesterol-fed rabbits. III. Intracellular localization of cholesterol and cholesteryl ester. , 1979, Laboratory investigation; a journal of technical methods and pathology.
[52] M. Brown,et al. Degradation of cationized low density lipoprotein and regulation of cholesterol metabolism in homozygous familial hypercholesterolemia fibroblasts. , 1976, Proceedings of the National Academy of Sciences of the United States of America.
[53] R. Havel,et al. The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum. , 1955, The Journal of clinical investigation.
[54] O. H. Lowry,et al. Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.