The placement of Bluetooth beacon has immediate impact on the accuracy and stability of indoor positioning. Affected by the shelter of building and human, Bluetooth shows uncertain spatial transmission characteristics. Therefore, the scientific deployment of the beacon nodes is closely related to the indoor space environment. In the study of positioning technology using Bluetooth, some scholars have discussed the deployment of Bluetooth beacon in different scenarios. In the principle of avoiding shelter, general method deploys Bluetooth beacon under the triangular grid staggered deployment with 6-8 meters of equal spacing. Although this kind of method can provide good positioning accuracy with a high-density placed Bluetooth, it also increases the cost and cause waste of resources. Bluetooth combined with INS (Inertial Navigation System) is a new trend in indoor positioning and has good performance in application. However current research mostly focused on the fusion of the two techniques during the positioning process, but rarely considers the influence of combinatorial positioning on the deployment of Bluetooth beacon. Also the study of the placement of Bluetooth has not yet fully utilized the characteristics of INS. This paper proposes an optimal Bluetooth beacon nodes placement method using the minimum number of beacons in the general space scene, making LBS 2018 http://doi.org/10.3929/ethz-b-000225588