Patterns of growth in verbal abilities among children with autism spectrum disorder.

Verbal skills were assessed at approximately ages 2, 3, 5, and 9 years for 206 children with a clinical diagnosis of autism (n = 98), pervasive developmental disorders-not otherwise specified (PDD-NOS; n = 58), or nonspectrum developmental disabilities (n = 50). Growth curve analyses were used to analyze verbal skills trajectories over time. Nonverbal IQ and joint attention emerged as strong positive predictors of verbal outcome. The gap between the autism and other 2 groups widened with time as the latter improved at a higher rate. However, there was considerable variability within diagnostic groups. Children with autism most at risk for more serious language impairments later in life can be identified with considerable accuracy at a very young age, while improvement can range from minimal to dramatic.

[1]  S. Bradley-Johnson Mullen Scales of Early Learning , 1997 .

[2]  C. Lord,et al.  A follow-up study of high-functioning autistic children. , 1992, Journal of child psychology and psychiatry, and allied disciplines.

[3]  G. Delong Autism , 1999, Neurology.

[4]  S. Rogers Play Interventions for Young Children with Autism Spectrum Disorders. , 2005 .

[5]  F. Volkmar,et al.  Handbook of Autism and Pervasive Developmental Disorders , 1987 .

[6]  P. Diggle,et al.  Analysis of Longitudinal Data. , 1997 .

[7]  C. Lord,et al.  The Pre-Linguistic Autism Diagnostic Observation Schedule , 1995, Journal of autism and developmental disorders.

[8]  C. Lord,et al.  Regression and word loss in autistic spectrum disorders. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[9]  P Howlin,et al.  Autism and developmental receptive language disorder--a follow-up comparison in early adult life. II: Social, behavioural, and psychiatric outcomes. , 2000, Journal of child psychology and psychiatry, and allied disciplines.

[10]  G. Baird,et al.  Outcome at 7 years of children diagnosed with autism at age 2: predictive validity of assessments conducted at 2 and 3 years of age and pattern of symptom change over time. , 2005, Journal of child psychology and psychiatry, and allied disciplines.

[11]  C. Gillberg,et al.  Outcome and prognostic factors in infantile autism and similar conditions: A population-based study of 46 cases followed through puberty , 1987, Journal of autism and developmental disorders.

[12]  Jonathan Green,et al.  A new social communication intervention for children with autism: pilot randomised controlled treatment study suggesting effectiveness. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[13]  M. Sigman,et al.  Continuity and change in the social competence of children with autism, Down syndrome, and developmental delays. , 1999, Monographs of the Society for Research in Child Development.

[14]  C. Lord,et al.  The Autism Diagnostic Observation Schedule: Revised Algorithms for Improved Diagnostic Validity , 2007, Journal of autism and developmental disorders.

[15]  C. Lord,et al.  Stability of assessment results of autistic and non-autistic language-impaired children from preschool years to early school age. , 1989, Journal of child psychology and psychiatry, and allied disciplines.

[16]  G. Dawson,et al.  Early social attention impairments in autism: social orienting, joint attention, and attention to distress. , 2004, Developmental psychology.

[17]  M. Sigman,et al.  Improvement in Cognitive and Language Skills from Preschool to Adolescence in Autism , 2005, Journal of autism and developmental disorders.

[18]  R. Adolphs,et al.  Neuroanatomical substrates of social cognition dysfunction in autism. , 2004, Mental retardation and developmental disabilities research reviews.

[19]  R. Kobayashi,et al.  A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, Japan , 1992, Journal of autism and developmental disorders.

[20]  A. Neal,et al.  Neural plasticity, joint attention, and a transactional social-orienting model of autism* , 2000 .

[21]  Paul J. Yoder,et al.  Predicting Spoken Language Level in Children with Autism Spectrum Disorders , 2001, Autism : the international journal of research and practice.

[22]  L Atkinson,et al.  Fourteen-year follow-up of speech/language-impaired and control children: psychiatric outcome. , 2001, Journal of the American Academy of Child and Adolescent Psychiatry.

[23]  M. Rutter,et al.  Autism and developmental receptive language disorder--a comparative follow-up in early adult life. I: Cognitive and language outcomes. , 2000, Journal of child psychology and psychiatry, and allied disciplines.

[24]  M. Sigman,et al.  Relations Among Joint Attention, Amount of Intervention and Language Gain in Autism , 2004, Journal of autism and developmental disorders.

[25]  P. Mundy,et al.  A longitudinal study of joint attention and language development in autistic children , 1990, Journal of autism and developmental disorders.

[26]  G. Baird,et al.  Research into Early Intervention for Children with Autism and Related Disorders: Methodological and Design Issues , 2003, Autism : the international journal of research and practice.

[27]  Craig Newschaffer,et al.  Predictors of Language Acquisition in Preschool Children with Autism Spectrum Disorders , 2007, Journal of autism and developmental disorders.

[28]  T. Oakland,et al.  A Review of the Vineland Adaptive Behavior Scales, Survey Form , 1985 .

[29]  D. Wechsler Wechsler Intelligence Scale for Children , 2020, Definitions.

[30]  Tristram Smith,et al.  Randomized Trial of Intensive Early Intervention for Children With Pervasive Developmental Disorder , 2000 .

[31]  Brian Everitt,et al.  Statistical analysis of medical data : new developments , 2000 .

[32]  B. Leventhal,et al.  The Autism Diagnostic Observation Schedule—Generic: A Standard Measure of Social and Communication Deficits Associated with the Spectrum of Autism , 2000, Journal of autism and developmental disorders.

[33]  G. Baird,et al.  Predicting language outcome in infants with autism and pervasive developmental disorder. , 2003, International journal of language & communication disorders.

[34]  Connie Kasari,et al.  Early intervention in autism: Joint attention and symbolic play , 2000 .

[35]  M. Sigman,et al.  The Behaviors of Parents of Children with Autism Predict the Subsequent Development of Their Children's Communication , 2002, Journal of autism and developmental disorders.

[36]  M. Rutter,et al.  Mothers' speech to autistic children: a preliminary causal analysis. , 1989, Journal of child psychology and psychiatry, and allied disciplines.

[37]  K. Roeder,et al.  A SAS Procedure Based on Mixture Models for Estimating Developmental Trajectories , 2001 .

[38]  G. Molenberghs,et al.  Linear Mixed Models for Longitudinal Data , 2001 .

[39]  P. J. Krantz,et al.  The facilitative effects of incidental teaching on preposition use by autistic children. , 1985, Journal of applied behavior analysis.

[40]  W. Stone,et al.  Follow-up of children with autism spectrum disorders from age 2 to age 9 , 2006, Autism : the international journal of research and practice.

[41]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[42]  M. Stevens,et al.  Subgroups of children with autism by cluster analysis: a longitudinal examination. , 2000, Journal of the American Academy of Child and Adolescent Psychiatry.

[43]  C. Lord,et al.  Autism from 2 to 9 years of age. , 2006, Archives of general psychiatry.