of Clinical and Basic Cardiology

beta-blockers improve prognosis post myocardial infarction; benefit being demonstrated in many categories, particular value has been shown in patients with poor left ventricular function. The first non-predicted use of beta-blockers demonstrated was their antihypertensive effect. They are now accepted by major international guidelines as first line therapy. Beta 1 -selective agents are more effective than non-selective agents, and contrary to some earlier evidence based on non-selective agents, they are often effective in younger (under 65) black patients. Beta-blockers have been shown to improve prognosis in younger patients while in the elderly, diuretics appear superior in primary prevention. Since