Depletion of naive T cells using clinical grade magnetic CD45RA beads: a new approach for GVHD prophylaxis

[1]  R. Handgretinger.  Negative depletion of CD3+ and TcR&agr;&bgr;+ T cells , 2012, Current opinion in hematology.

[2]  S. Tenzer,et al.  Varicella-zoster virus glycoproteins B and E are major targets of CD4+ and CD8+ T cells reconstituting during zoster after allogeneic transplantation , 2012, Haematologica.

[3]  M. Kester,et al.  Successful generation of primary virus-specific and anti-tumor T-cell responses from the naïve donor T-cell repertoire is determined by the balance between antigen-specific precursor T cells and regulatory T cells , 2011, Haematologica.

[4]  M. Theobald,et al.  Alloreactive and leukemia-reactive T cells are preferentially derived from naïve precursors in healthy donors: implications for immunotherapy with memory T cells , 2011, Haematologica.

[5]  H. Kohrt,et al.  CD8+CD44(hi) but not CD4+CD44(hi) memory T cells mediate potent graft antilymphoma activity without GVHD. , 2011, Blood.

[6]  K. Rezvani.  Peptide vaccine therapy for leukemia , 2011, International journal of hematology.

[7]  M. Theobald,et al.  IL-21-treated naive CD45RA+ CD8+ T cells represent a reliable source for producing leukemia-reactive cytotoxic T lymphocytes with high proliferative potential and early differentiation phenotype , 2011, Cancer Immunology, Immunotherapy.

[8]  H. Einsele,et al.  Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation. , 2010, Blood.

[9]  M. Leppert,et al.  Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells. , 2010, Blood.

[10]  H. Einsele,et al.  Immune reconstitution after allogeneic transplantation and expanding options for immunomodulation: an update. , 2010, Blood.

[11]  A. Amir,et al.  Allo-HLA reactivity of virus-specific memory T cells is common. , 2010, Blood.

[12]  Shamsul A. Khan,et al.  Selective Depletion of Alloreactive T Lymphocytes Using Patient-Derived Nonhematopoietic Stimulator Cells in Allograft Engineering , 2008, Transplantation.

[13]  V. Appay,et al.  Phenotype and function of human T lymphocyte subsets: Consensus and issues , 2008, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[14]  C. Huber,et al.  Acute myeloid leukemia (AML)-reactive cytotoxic T lymphocyte clones rapidly expanded from CD8(+) CD62L((high)+) T cells of healthy donors prevent AML engraftment in NOD/SCID IL2Rgamma(null) mice. , 2008, Experimental hematology.

[15]  R. Andreesen,et al.  Only the CD45RA+ subpopulation of CD4+CD25high T cells gives rise to homogeneous regulatory T-cell lines upon in vitro expansion. , 2006, Blood.

[16]  C. Huber,et al.  Preemptive Transfer of GMP-Grade CD8-Depleted Donor Lymphocytes after T-Cell Depleted Reduced-Intensity Transplantation. , 2005 .

[17]  D. Roelen,et al.  The putative mechanism of the immunomodulating effect of HLA-DR shared allogeneic blood transfusions on the alloimmune response. , 2005, Transfusion medicine reviews.

[18]  C. Craddock,et al.  Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers , 2005, The Journal of experimental medicine.

[19]  A. Barrett,et al.  Selective depletion strategies in allogeneic stem cell transplantation. , 2005, Cytotherapy.

[20]  S. Alexander,et al.  Human CD62L- memory T cells are less responsive to alloantigen stimulation than CD62L+ naive T cells: potential for adoptive immunotherapy and allodepletion. , 2004, Blood.

[21]  Virander S. Chauhan,et al.  Flexibility in MHC and TCR Recognition: Degenerate Specificity at the T Cell Level in the Recognition of Promiscuous Th Epitopes Exhibiting No Primary Sequence Homology , 2001, The Journal of Immunology.

[22]  D. Speiser,et al.  High Frequencies of Naive Melan-a/Mart-1–Specific Cd8+ T Cells in a Large Proportion of Human Histocompatibility Leukocyte Antigen (Hla)-A2 Individuals , 1999, The Journal of experimental medicine.

[23]  Gastone Castellani,et al.  CD45 isoforms expression on CD4+ and CD8+ T cells throughout life, from newborns to centenarians: implications for T cell memory , 1996, Mechanisms of Ageing and Development.

[24]  J. Burrows,et al.  An alloresponse in humans is dominated by cytotoxic T lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: implications for graft-versus-host disease , 1994, The Journal of experimental medicine.

[25]  H. Sytwu,et al.  Cell transplantation. , 2014, Journal of neurosurgery.

[26]  Benny J Chen.  Allogeneic memory T cell response. , 2008, Biology of Blood and Marrow Transplantation.

[27]  C. Huber,et al.  Prophylactic transfer of CD8-depleted donor lymphocytes after T-cell-depleted reduced-intensity transplantation. , 2007, Blood.