A k2A-positive Klebsiella pneumoniae causes liver and brain abscess in a Saint Kitt's man

Klebsiella pneumoniae isolated in community-acquired pneumonia is increasingly found in primary pyogenic liver abscesses. The presence of magA in K. pneumoniae has been implicated in hypermucoviscosity and virulence of liver abscess isolates. The K2 serotype has also been strongly associated with hypervirulence. We report the isolation of non-magA, K2 K. pneumoniae strain from a liver abscess of a Saint Kitt's man who survived the invasive syndrome.

[1]  Ling-Hui Li,et al.  Genome Sequencing and Comparative Analysis of Klebsiella pneumoniae NTUH-K2044, a Strain Causing Liver Abscess and Meningitis , 2009, Journal of bacteriology.

[2]  Y. Keynan,et al.  The changing face of Klebsiella pneumoniae infections in the community. , 2007, International journal of antimicrobial agents.

[3]  R. Domiati-Saad,et al.  Invasive Klebsiella pneumoniae syndrome in North America. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[4]  Shih-Feng Liu,et al.  Acute respiratory failure in adult patients with dengue virus infection. , 2007, The American journal of tropical medicine and hygiene.

[5]  W. Ko,et al.  Polymerase chain reaction analysis for detecting capsule serotypes K1 and K2 of Klebsiella pneumoniae causing abscesses of the liver and other sites. , 2007, The Journal of infectious diseases.

[6]  Y. Keynan,et al.  Pyogenic liver abscess caused by hypermucoviscous Klebsiella pneumoniae , 2007, Scandinavian journal of infectious diseases.

[7]  Te‐Li Chen,et al.  Capsular Serotype K1 or K2, Rather than magA and rmpA, Is a Major Virulence Determinant for Klebsiella pneumoniae Liver Abscess in Singapore and Taiwan , 2006, Journal of Clinical Microbiology.

[8]  W. Ko,et al.  Clinical implications of hypermucoviscosity phenotype in Klebsiella pneumoniae isolates: association with invasive syndrome in patients with community‐acquired bacteraemia , 2006, Journal of internal medicine.

[9]  Shan-Chwen Chang,et al.  Genetic determinants of capsular serotype K1 of Klebsiella pneumoniae causing primary pyogenic liver abscess. , 2006, The Journal of infectious diseases.

[10]  Kuender D Yang,et al.  Clinical characteristics and risk factors for concurrent bacteremia in adults with dengue hemorrhagic fever. , 2005, The American journal of tropical medicine and hygiene.

[11]  Chia-Tung Shun,et al.  A Novel Virulence Gene in Klebsiella pneumoniae Strains Causing Primary Liver Abscess and Septic Metastatic Complications , 2004, The Journal of experimental medicine.

[12]  R. Podschun,et al.  Klebsiella spp. as Nosocomial Pathogens: Epidemiology, Taxonomy, Typing Methods, and Pathogenicity Factors , 1998, Clinical Microbiology Reviews.

[13]  S. H. Han.  Review of hepatic abscess from Klebsiella pneumoniae. An association with diabetes mellitus and septic endophthalmitis. , 1995, The Western journal of medicine.