Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation
暂无分享,去创建一个
Ping Wang | Yanhui Xu | R. Gong | Jingdong Cheng | Huirong Yang | Lixiang Ma | Jian Fang | Ze Li
[1] S. Anant,et al. DNA Methyltransferases: A Novel Target for Prevention and Therapy , 2013, Front. Oncol..
[2] G. Liang,et al. Synergistic Re-Activation of Epigenetically Silenced Genes by Combinatorial Inhibition of DNMTs and LSD1 in Cancer Cells , 2013, PloS one.
[3] Anindya Dutta,et al. Deubiquitination of Tip60 by USP7 Determines the Activity of the p53-Dependent Apoptotic Pathway , 2013, Molecular and Cellular Biology.
[4] Zachary D. Smith,et al. DNA methylation: roles in mammalian development , 2013, Nature Reviews Genetics.
[5] Yan Sun,et al. Human embryonic stem cell-derived GABA neurons correct locomotion deficits in quinolinic acid-lesioned mice. , 2012, Cell stem cell.
[6] M. Sowa,et al. M phase phosphorylation of the epigenetic regulator UHRF1 regulates its physical association with the deubiquitylase USP7 and stability , 2012, Proceedings of the National Academy of Sciences.
[7] A. Guimarães,et al. Analysis of p16CDKN2A Methylation and HPV-16 Infection in Oral Mucosal Dysplasia , 2012, Pathobiology.
[8] T. Sixma,et al. Mechanism of USP7/HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase. , 2011, Molecular cell.
[9] Peter A. Jones,et al. A decade of exploring the cancer epigenome — biological and translational implications , 2011, Nature Reviews Cancer.
[10] H. Leonhardt,et al. Regulation of DNA methyltransferase 1 by interactions and modifications , 2011, Nucleus.
[11] E. Kremmer,et al. The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1 , 2011, Nucleic acids research.
[12] F. Fuks,et al. Regulation of mammalian DNA methyltransferases: a route to new mechanisms , 2011, EMBO reports.
[13] T. Sharif,et al. Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties , 2011, Journal of experimental & clinical cancer research : CR.
[14] B. Nicholson,et al. The Multifaceted Roles of USP7: New Therapeutic Opportunities , 2011, Cell Biochemistry and Biophysics.
[15] D. Patel,et al. Structure of DNMT1-DNA Complex Reveals a Role for Autoinhibition in Maintenance DNA Methylation , 2011, Science.
[16] H. Leonhardt,et al. Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1 , 2011, Journal of cellular biochemistry.
[17] Yiqing Zhao,et al. DNMT1 Stability Is Regulated by Proteins Coordinating Deubiquitination and Acetylation-Driven Ubiquitination , 2010, Science Signaling.
[18] J. Shea,et al. Phenotype and Genotype of Pancreatic Cancer Cell Lines , 2010, Pancreas.
[19] M. Mann,et al. Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions , 2009, Science.
[20] Ying Zhang,et al. DUBs and cancer: The role of deubiquitinating enzymes as oncogenes, non-oncogenes and tumor suppressors , 2009, Cell cycle.
[21] Y. Gong,et al. Significance of DNA methyltransferase-1 and histone deacetylase-1 in pancreatic cancer. , 2009, Oncology reports.
[22] S. Jacobsen,et al. Regulation of DNMT1 stability through SET7-mediated lysine methylation in mammalian cells , 2009, Proceedings of the National Academy of Sciences.
[23] M. Bernstein,et al. Preclinical evaluation of the antineoplastic action of 5-aza-2'-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cells , 2008, Cancer Cell International.
[24] Pier Paolo Pandolfi,et al. The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network , 2008, Nature.
[25] P. Atadja,et al. Inhibition of Histone Deacetylases Promotes Ubiquitin-Dependent Proteasomal Degradation of DNA Methyltransferase 1 in Human Breast Cancer Cells , 2008, Molecular Cancer Research.
[26] K. Mitsuya,et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA , 2007, Nature.
[27] T. Ichisaka,et al. Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.
[28] J. Qin,et al. ICBP90, a Novel Methyl K9 H3 Binding Protein Linking Protein Ubiquitination with Heterochromatin Formation , 2007, Molecular and Cellular Biology.
[29] S. Jacobsen,et al. UHRF1 Plays a Role in Maintaining DNA Methylation in Mammalian Cells , 2007, Science.
[30] S. Gery,et al. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells , 2007, International journal of cancer.
[31] Randy J. Read,et al. Phaser crystallographic software , 2007, Journal of applied crystallography.
[32] R. Larson,et al. Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] N. Grishin,et al. Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. , 2006, Molecular cell.
[34] John M Bennett,et al. Decitabine improves patient outcomes in myelodysplastic syndromes , 2006, Cancer.
[35] Yigong Shi,et al. Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53–MDM2 Pathway , 2006, PLoS biology.
[36] S. Hirohashi,et al. Increased DNA methyltransferase 1 (DNMT1) protein expression in precancerous conditions and ductal carcinomas of the pancreas , 2005, Cancer science.
[37] T. Bestor,et al. Eukaryotic cytosine methyltransferases. , 2005, Annual review of biochemistry.
[38] C. Arrowsmith,et al. Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1 implications for EBV-mediated immortalization. , 2005, Molecular cell.
[39] F. Karch,et al. GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. , 2005, Molecular cell.
[40] P. Emsley,et al. High-resolution structure of a retroviral protease folded as a monomer , 2011, Acta Crystallographica Section D: Biological Crystallography.
[41] James B. Mitchell,et al. Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach. , 2004, Cancer cell.
[42] C. Arrowsmith,et al. Protein Interaction Domains of the Ubiquitin-specific Protease, USP7/HAUSP* , 2003, Journal of Biological Chemistry.
[43] M. Bernstein,et al. Preclinical evaluation of antineoplastic activity of inhibitors of DNA methylation (5-aza-2'-deoxycytidine) and histone deacetylation (trichostatin A, depsipeptide) in combination against myeloid leukemic cells. , 2003, Leukemia research.
[44] A. Bird,et al. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals , 2003, Nature Genetics.
[45] Randy J Read,et al. Electronic Reprint Biological Crystallography Phenix: Building New Software for Automated Crystallographic Structure Determination Biological Crystallography Phenix: Building New Software for Automated Crystallographic Structure Determination , 2022 .
[46] R. Everett,et al. A novel ubiquitin‐specific protease is dynamically associated with the PML nuclear domain and binds to a herpesvirus regulatory protein , 1997, The EMBO journal.
[47] J. Thornton,et al. PROCHECK: a program to check the stereochemical quality of protein structures , 1993 .
[48] S. Pradhan,et al. Regulation of expression and activity of DNA (cytosine-5) methyltransferases in mammalian cells. , 2011, Progress in molecular biology and translational science.
[49] E. Li,et al. The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation , 2009, Nature Genetics.
[50] A. Bird. DNA methylation patterns and epigenetic memory. , 2002, Genes & development.
[51] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[52] Z. Otwinowski,et al. Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.