“Remdesivir”

[1]  Diana Tejada,et al.  Clinical course of patients with severe COVID-19 pneumonia treated with remdesivir: A real-life study , 2022, PloS one.

[2]  Tamer Z. Attia,et al.  Novel environment friendly TLC-densitometric method for the determination of anti-coronavirus drugs “Remdesivir and Favipiravir”: Green assessment with application to pharmaceutical formulations and human plasma , 2021, Microchemical Journal.

[3]  S. Chandrasekhar,et al.  Total synthesis of remdesivir , 2021, Tetrahedron Letters.

[4]  Ángel Piñeiro,et al.  Remdesivir interactions with sulphobutylether-β-cyclodextrins: A case study using selected substitution patterns , 2021, Journal of Molecular Liquids.

[5]  G. Peterson,et al.  Efficacy and safety of remdesivir in hospitalised COVID-19 patients: a systematic review and meta-analysis , 2021, Infection.

[6]  Lihong Liu,et al.  Quantitative HPLC-MS/MS determination of Nuc, the active metabolite of remdesivir, and its pharmacokinetics in rat , 2021, Analytical and Bioanalytical Chemistry.

[7]  Miranda F. Kamal,et al.  Accelerated Stability Study of the Ester Prodrug Remdesivir; Recently FDA Approved Covid-19 Antiviral Using RP-HPLC with Fluorimetric and Diode Array Detection. , 2021, Biomedical chromatography : BMC.

[8]  S. Deb,et al.  ADME and Pharmacokinetic Properties of Remdesivir: Its Drug Interaction Potential , 2021, Pharmaceuticals.

[9]  F. Belal,et al.  Green and sensitive spectrofluorimetric determination of Remdesivir, an FDA approved SARS-CoV-2 candidate antiviral; application in pharmaceutical dosage forms and spiked human plasma. , 2021, Analytical methods : advancing methods and applications.

[10]  Sivakumar Sekharan,et al.  Selecting a stable solid form of remdesivir using microcrystal electron diffraction and crystal structure prediction , 2021, RSC advances.

[11]  S. Shamshuddin,et al.  A Novel Liquid Chromatographic Method for the Quantitative Determination of Degradation Products in Remdesivir Injectable Drug product. , 2021, Journal of chromatographic science.

[12]  P. German,et al.  Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor , 2021, Clinical Pharmacokinetics.

[13]  H. Zhang,et al.  The efficacy and safety of remdesivir in the treatment of patients with COVID-19: a systematic review and meta-analysis , 2021, medRxiv.

[14]  P. German,et al.  Validation of LC-MS/MS methods for determination of remdesivir and its metabolites GS-441524 and GS-704277 in acidified human plasma and their application in COVID-19 related clinical studies , 2021, Analytical Biochemistry.

[15]  I. Kumar.  A review on pharmacokinetics, pharmacodynamics and clinical aspects of remdesivir and favipiravir for the treatment of coronavirus disease , 2021 .

[16]  I. Bulduk,et al.  A comparative study of HPLC and UV spectrophotometric methods for remdesivir quantification in pharmaceutical formulations , 2021, Acta Chromatographica.

[17]  Hongzhen Bai,et al.  Two polymorphs of remdesivir: crystal structure, solubility, and pharmacokinetic study , 2021 .

[18]  Yaser Pashaei.  Analytical methods for the determination of remdesivir as a promising antiviral candidate drug for the COVID-19 pandemic. , 2020, Drug discoveries & therapeutics.

[19]  C. Ke,et al.  Challenges and stepwise fit-for-purpose optimization for bioanalyses of remdesivir metabolites nucleotide monophosphate and triphosphate in mouse tissues using LC–MS/MS , 2020, Journal of Pharmaceutical and Biomedical Analysis.

[20]  J. Rybniker,et al.  Remdesivir against COVID-19 and Other Viral Diseases , 2020, Clinical Microbiology Reviews.

[21]  R. Williams,et al.  Development of Remdesivir as a Dry Powder for Inhalation by Thin Film Freezing , 2020, bioRxiv.

[22]  D. Annane,et al.  Quantification of plasma remdesivir and its metabolite GS-441524 using liquid chromatography coupled to tandem mass spectrometry. Application to a Covid-19 treated patient , 2020, Clinical chemistry and laboratory medicine.

[23]  Andrew C. Stevens,et al.  Development of a Large-Scale Cyanation Process Using Continuous Flow Chemistry En Route to the Synthesis of Remdesivir , 2020, Organic process research & development.

[24]  G. di Perri,et al.  Development and validation of a UHPLC-MS/MS method for quantification of the prodrug remdesivir and its metabolite GS-441524: a tool for clinical pharmacokinetics of SARS-CoV-2/COVID-19 and Ebola virus disease , 2020, The Journal of antimicrobial chemotherapy.

[25]  M. Kushnir,et al.  Theoretical Description for Anti-COVID-19 Drug Remdesivir Electrochemical Determination, Assisted by Squaraine Dye–Ag2O2 Composite , 2020 .

[26]  B. Kapoor,et al.  Development and Validation of UV Spectroscopic Method for Estimation of Baricitinib , 2019, Journal of Drug Delivery and Therapeutics.

[27]  William A. Lee,et al.  Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses , 2017, Journal of medicinal chemistry.

[28]  William A. Lee,et al.  Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys , 2016, Nature.

[29]  William A. Lee,et al.  Nucleotide analogue prodrug tenofovir disoproxil enhances lymphoid cell loading following oral administration in monkeys. , 2009, Molecular pharmaceutics.