A case of schizophrenia with meige syndrome induced by perospirone successfully treated with biperiden.

To the Editor: Meige syndrome is a focal dystonia involving symmetrical blepharospasm and oromandibular dystonia. The typical symptom is difficulty in keeping the eyelids open. This syndrome has been reported to be induced by several atypical antipsychotics, including risperidone, olanzapine, quetiapine, and aripiprazole. Here, we report a case of Meige syndrome emerging with an atypical antipsychotic, perospirone, which was successfully treated with biperiden. To our knowledge, this is the first report of Meige syndrome induced by perospirone.

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