Health status measurement in chronic obstructive pulmonary disease

Health status measurement is a common feature of studies in chronic obstructive pulmonary disease (COPD). This review assesses recent evidence for the validity of these measurements and their role as measures of the overall impact of the disease on the patient's daily life and wellbeing. It reviews the mostly widely used COPD specific questionnaires and examines the contribution that they make to an assessment of the overall effect of treatment. Finally, it addresses the question of how symptomatic benefit may be assessed in individual patients in routine practice.

[1]  M. R. Mölken,et al.  An empirical comparison of the St George's Respiratory Questionnaire (SGRQ) and the Chronic Respiratory Disease Questionnaire (CRQ) in a clinical trial setting. , 1999, Thorax.

[2]  G. Guyatt,et al.  Quality of life in patients with chronic airflow limitation. , 1987, British journal of diseases of the chest.

[3]  P. Jones,et al.  Asthma health status measurement in clinical practice: validity of a new short and simple instrument. , 1998, Respiratory medicine.

[4]  E. Wouters,et al.  Determinants of health-related quality of life in patients with chronic obstructive pulmonary disease. , 1996, Thorax.

[5]  P M Calverley,et al.  Health status deterioration in patients with chronic obstructive pulmonary disease. , 2001, American journal of respiratory and critical care medicine.

[6]  P. Jones,et al.  A comparison of global questions versus health status questionnaires as measures of the severity and impact of asthma. , 1999, The European respiratory journal.

[7]  C Pichard,et al.  Health-related quality of life in patients under long-term oxygen therapy: a home-based descriptive study. , 1997, Respiratory medicine.

[8]  P. Jones,et al.  Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hypercapnic COPD. , 1995, American journal of respiratory and critical care medicine.

[9]  P. Jones,et al.  Analysis of factors that characterize health impairment in patients with chronic respiratory failure. Quality of Life in Chronic Respiratory Failure Group. , 1999, The European respiratory journal.

[10]  M. Morgan,et al.  A short outpatient pulmonary rehabilitation programme: immediate and longer-term effects on exercise performance and quality of life. , 1998, Respiratory medicine.

[11]  N. Jones,et al.  Dyspnea and leg effort during incremental cycle ergometry. , 1992, The American review of respiratory disease.

[12]  P. Jones,et al.  Differentiation between the intensity of breathlessness and the distress it evokes in normal subjects during exercise. , 1991, Clinical science.

[13]  N. Jones,et al.  Respiratory muscles and dyspnea. , 1988, Clinics in chest medicine.

[14]  P. Jones,et al.  Usefulness of the Medical Research Council (MRC) dyspnoea scale as a measure of disability in patients with chronic obstructive pulmonary disease , 1999, Thorax.

[15]  K. E. Bendstrup,et al.  Out-patient rehabilitation improves activities of daily living, quality of life and exercise tolerance in chronic obstructive pulmonary disease. , 1997, The European respiratory journal.

[16]  T. Seemungal,et al.  Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease. , 1998, American journal of respiratory and critical care medicine.

[17]  F. Maltais,et al.  Aerobic and strength training in patients with chronic obstructive pulmonary disease. , 1999, American journal of respiratory and critical care medicine.

[18]  N. Payne,et al.  Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial , 2000, The Lancet.

[19]  R. Zuwallack,et al.  Body composition and health-related quality of life in patients with obstructive airways disease. , 1997, The European respiratory journal.

[20]  P. Jones,et al.  Home assessment of activities of daily living in patients with severe chronic obstructive pulmonary disease on long-term oxygen therapy. , 1997, The European respiratory journal.

[21]  P. Jones,et al.  Quality of life in patients with chronic obstructive pulmonary disease and severe hypoxaemia. , 1996, Thorax.

[22]  M. Connolly,et al.  Impact of obstructive airways disease on quality of life in older adults. , 1996, Thorax.

[23]  M. Tsukino,et al.  Comparison of discriminative properties among disease-specific questionnaires for measuring health-related quality of life in patients with chronic obstructive pulmonary disease. , 1998, American journal of respiratory and critical care medicine.

[24]  P. Jones,et al.  Development and validation of a standardized measure of activity of daily living in patients with severe COPD: the London Chest Activity of Daily Living scale (LCADL). , 2000, Respiratory medicine.

[25]  J. Wright,et al.  The minimal important difference: who's to say what is important? , 1996, Journal of clinical epidemiology.

[26]  P. Jones,et al.  Quality of life changes in COPD patients treated with salmeterol. , 1997, American journal of respiratory and critical care medicine.

[27]  G. Guyatt,et al.  Measurement of health status. Ascertaining the minimal clinically important difference. , 1989, Controlled clinical trials.

[28]  A. Grassino,et al.  Role of inspiratory muscle dysfunction in chronic hypercapnia. , 1990, Chest.

[29]  T. Weaver,et al.  The development and psychometric evaluation of the Pulmonary Functional Status Scale: an instrument to assess functional status in pulmonary disease. , 1998, Journal of cardiopulmonary rehabilitation.

[30]  S. Spencer,et al.  Randomised, double blind, placebo controlled study of fluticasone propionate in patients with moderate to severe chronic obstructive pulmonary disease: the ISOLDE trial , 2000, BMJ : British Medical Journal.

[31]  R. Zuwallack,et al.  Improvement in Quality of Life Is Unrelated to Improvement in Excercise Endurance After Outpatient Pulmonary Rehabilitation , 1993 .

[32]  M. Belman,et al.  Inhaled bronchodilators reduce dynamic hyperinflation during exercise in patients with chronic obstructive pulmonary disease. , 1996, American journal of respiratory and critical care medicine.

[33]  P. Jones,et al.  A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire. , 1992, The American review of respiratory disease.

[34]  P. Jones,et al.  The St George's Respiratory Questionnaire. , 1991, Respiratory medicine.

[35]  J. G. Douglas,et al.  Quality of life and hospital re-admission in patients with chronic obstructive pulmonary disease. , 1997, Thorax.

[36]  G. Guyatt,et al.  Generic and specific measurement of health-related quality of life in a clinical trial of respiratory rehabilitation. , 1999, Journal of clinical epidemiology.

[37]  M J Connolly,et al.  Quality of life in elderly patients with COPD: measurement and predictive factors. , 1998, Respiratory medicine.

[38]  M. Wittmann [Meta-analysis of respiratory rehabilitation in chronic obstructive pulmonary disease]. , 1997, Pneumologie.

[39]  S. Lareau,et al.  Functional status instruments: outcome measure in the evaluation of patients with chronic obstructive pulmonary disease. , 1996, Heart & lung : the journal of critical care.

[40]  E. Wouters,et al.  Evidence for a relation between metabolic derangements and increased levels of inflammatory mediators in a subgroup of patients with chronic obstructive pulmonary disease. , 1996, Thorax.

[41]  G. Guyatt,et al.  On the debate over methods for estimating the clinically important difference. , 1996, Journal of clinical epidemiology.

[42]  A. Goris,et al.  Tissue depletion and health related quality of life in patients with chronic obstructive pulmonary disease. , 2000, Respiratory medicine.

[43]  J. Brazier,et al.  Comparison of outcome measures for patients with chronic obstructive pulmonary disease (COPD) in an outpatient setting. , 1997, Thorax.

[44]  G. Guyatt,et al.  Assessing the minimal important difference in symptoms: a comparison of two techniques. , 1996, Journal of clinical epidemiology.

[45]  P. Jones,et al.  Differentiation between the intensity of breathlessness and the distress it evokes in normal subjects during exercise. , 1991 .

[46]  T. W. van der Mark,et al.  Relation of lung function, maximal inspiratory pressure, dyspnoea, and quality of life with exercise capacity in patients with chronic obstructive pulmonary disease. , 1994, Thorax.

[47]  A. Grassino,et al.  Inspiratory muscle dysfunction and chronic hypercapnia in chronic obstructive pulmonary disease. , 1991, The American review of respiratory disease.

[48]  J. Dijkman,et al.  The development of the 'Quality-of-life for Respiratory Illness Questionnaire (QOL-RIQ)': a disease-specific quality-of-life questionnaire for patients with mild to moderate chronic non-specific lung disease. , 1997, Respiratory medicine.

[49]  P. Jones,et al.  A novel, short, and simple questionnaire to measure health-related quality of life in patients with chronic obstructive pulmonary disease. , 1999, American journal of respiratory and critical care medicine.

[50]  H. Magnussen,et al.  Factor analysis of changes in dyspnea and lung function parameters after bronchodilation in chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[51]  M. Sullivan,et al.  Functional status and well being in chronic obstructive pulmonary disease with regard to clinical parameters and smoking: a descriptive and comparative study. , 1996, Thorax.

[52]  C. van der Schans,et al.  Perception of fatigue and quality of life in patients with COPD. , 1998, Chest.

[53]  G. Guyatt,et al.  A measure of quality of life for clinical trials in chronic lung disease. , 1987, Thorax.

[54]  T. Seemungal,et al.  Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease. , 2000, American journal of respiratory and critical care medicine.

[55]  P. Jones,et al.  Randomized controlled trial of pulmonary rehabilitation in severe chronic obstructive pulmonary disease patients, stratified with the MRC dyspnoea scale. , 1998, The European respiratory journal.

[56]  E. Wouters,et al.  Nutritional depletion in relation to respiratory and peripheral skeletal muscle function in out-patients with COPD. , 1994, The European respiratory journal.

[57]  D. O’Donnell,et al.  Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. , 1999, American journal of respiratory and critical care medicine.

[58]  M. Decramer,et al.  Peripheral muscle weakness contributes to exercise limitation in COPD. , 1996, American journal of respiratory and critical care medicine.

[59]  Teresa M. Danawicz IMPROVEMENT IN THE QUALITY OF LIFE IS UNRELATED TO IMPROVEMENT IN THE EXERCISE ENDURANCE AFTER OUTPATIENT PULMONARY REHABILITATION. , 1995 .

[60]  G. Guyatt,et al.  Quality of life in patients with chronic respiratory disease: the Spanish version of the Chronic Respiratory Questionnaire (CRQ) , 1998, The European respiratory journal.

[61]  P. Jones Quality of life measurement for patients with diseases of the airways. , 1991, Thorax.