Biosensors for fermentation control.

Over the past year, biosensor development has been an active area of research. The actual application of biosensors in process monitoring and control is limited to a few cases, mainly as a result of difficulties relating to their long-range stability and their sensitivity to interfering compounds. Steam sterilization is no longer a problem though, as the great majority of sensors are part of flow-injection analysis systems.

[1]  John Villadsen,et al.  Flow-injection analysis of micromolar concentrations of glucose and lactate in fermentation media , 1992 .

[2]  Thomas Scheper,et al.  Immunological on-line detection of specific proteins during fermentation processes , 1991 .

[3]  N. Kiba,et al.  Column liquid chromatographic determination of sucrose and fructose with use of an enzyme reactor and spectrofluorimetric detection , 1992 .

[4]  Rolf D. Schmid,et al.  Optimisation of the biosensor for in situ fermentation monitoring of glucose concentration , 1991 .

[5]  J. Polster,et al.  Penicillinase optodes : substrate determinations using batch, continuous flow and flow injection analysis operation conditions , 1992 .

[6]  F. Jähnig,et al.  A biosensor based on the membrane protein lactose permease , 1992 .

[7]  Andreas Manz,et al.  An improved micro enzyme sensor for bioprocess monitoring by flow injection analysis , 1992 .

[8]  B. Maïsterrena,et al.  Reliable amperometric determination of glycerol and glycerol-3-phosphate with a bienzymatic nylon membrane electrode , 1992 .

[9]  Developing biosensors with pH-ISFET transducers utilizing lipid bilayer membranes with transport proteins , 1992 .

[10]  C. G. D. María,et al.  Sequential determination of glucose, fructose and sucrose by flow-injection analysis with immobilized enzyme reactors and spectrophotometric detection , 1992 .

[11]  K. Kitabatake,et al.  Amperometric detection of alcohol in beer using a flow cell and immobilized alcohol dehydrogenase. , 1991, Analytical Chemistry.

[12]  F. Plötz,et al.  Applications of biosensor systems for bioprocess monitoring , 1991 .

[13]  C. Tran-Minh,et al.  Determination of penicillin-V in standard solution and in fermentation broth by flow-injection analysis using fast-responding enzyme glass electrodes in different detection cells , 1992 .

[14]  J H Luong,et al.  Monitoring glutamine in mammalian cell cultures using an amperometric biosensor. , 1992, Biosensors & bioelectronics.

[15]  Ingrid G. Marenchic,et al.  Antibody- and receptor-based biosensors for detection and process control , 1991 .

[16]  Koon Gee Neoh,et al.  Microbial membrane-modified dissolved oxygen probe for rapid biochemical oxygen demand measurement , 1992 .

[17]  I. Bennion,et al.  A single mode fibre-optic evanescent wave biosensor. , 1992, Biosensors & bioelectronics.

[18]  Bo Mattiasson,et al.  Flow-injection ELISA for process monitoring and control , 1991 .

[19]  B. Danielsson,et al.  Recent investigations on calorimetric biosensors , 1992 .

[20]  M. Smyth,et al.  Determination of glutathione at enzyme-modified and unmodified glassy carbon electrodes , 1991 .

[21]  T. Kuwana,et al.  Ion channel sensors for glutamic acid. , 1991, Analytical chemistry.

[22]  M. Meyerhoff,et al.  Operation of ion-selective electrode detectors in the sub-Nernstian/linear response range: application to flow-injection/enzymatic determination of L-glutamine in bioreactor media. , 1991, Analytical chemistry.

[23]  R D Schmid,et al.  On-line determination of glucose and lactate concentrations in animal cell culture based on fibre optic detection of oxygen in flow-injection analysis. , 1992, Biosensors & bioelectronics.

[24]  Björn Persson,et al.  Selective detection in flow analysis based on the combination of immobilized enzymes and chemically modified electrodes , 1991 .

[25]  Roberta Virgili,et al.  Analysis of sensory and instrumental data on apricot purées with pattern recognition techniques , 1992 .

[26]  Kiyoshi Matsumoto,et al.  Determination of l-glutamate by amperometric flow-injection analysis using immobilized glutamate oxidase: manifold for simultaneous detection of component signal and blank signal , 1992 .

[27]  U. Prinzing,et al.  Flow-injection systems for the determination of oxidoreductase substrates : applications in food quality control and process monitoring , 1991 .

[28]  J H Luong,et al.  A chemiluminescence fiber-optic biosensor system for the determination of glutamine in mammalian cell cultures. , 1992, Biosensors & bioelectronics.

[29]  C. Tran-Minh,et al.  Rapid measurement of penicillin contained in complex media using enzyme-loaded glass electrodes , 1991 .

[30]  U. Wollenberger,et al.  A lysine dehydrogenase-based electrode for biosensing of L-lysine. , 1992, Biosensors & bioelectronics.