Counterregulation of cAMP-directed kinase activities controls ciliogenesis

[1]  J. Höhfeld,et al.  The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover , 2017, Cell.

[2]  S. Züchner,et al.  STUB1/CHIP mutations cause Gordon Holmes syndrome as part of a widespread multisystemic neurodegeneration: evidence from four novel mutations , 2017, Orphanet Journal of Rare Diseases.

[3]  B. Dynlacht,et al.  Cilium assembly and disassembly , 2016, Nature Cell Biology.

[4]  Susan S. Taylor,et al.  Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling , 2016, Proceedings of the National Academy of Sciences.

[5]  B. Dynlacht,et al.  Tethering of an E3 ligase by PCM1 regulates the abundance of centrosomal KIAA0586/Talpid3 and promotes ciliogenesis , 2016, eLife.

[6]  P. Jackson,et al.  The primary cilium as a cellular receiver: organizing ciliary GPCR signaling. , 2016, Current opinion in cell biology.

[7]  Junmin Pan,et al.  A NIMA-related kinase, CNK4, regulates ciliary stability and length , 2016, Molecular biology of the cell.

[8]  Marco Y. Hein,et al.  A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances , 2015, Cell.

[9]  L. Rinaldi,et al.  A dynamic interface between ubiquitylation and cAMP signaling , 2015, Front. Pharmacol..

[10]  S. Neuhauss,et al.  MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma , 2015, Proceedings of the National Academy of Sciences.

[11]  E. Nigg,et al.  The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis , 2015, Journal of Cell Science.

[12]  Saikat Mukhopadhyay,et al.  Primary cilium and sonic hedgehog signaling during neural tube patterning: Role of GPCRs and second messengers , 2015, Developmental neurobiology.

[13]  N. Katsanis,et al.  Metabolic regulation and energy homeostasis through the primary Cilium. , 2015, Cell metabolism.

[14]  J. Gestwicki,et al.  Targeting Hsp90/Hsp70-based protein quality control for treatment of adult onset neurodegenerative diseases. , 2015, Annual review of pharmacology and toxicology.

[15]  A. Hyman,et al.  Pericentriolar material structure and dynamics , 2014, Philosophical Transactions of the Royal Society B: Biological Sciences.

[16]  M. Kirschner,et al.  The master cell cycle regulator APC-Cdc20 regulates ciliary length and disassembly of the primary cilium , 2014, eLife.

[17]  S. Züchner,et al.  Phenotype and frequency of STUB1 mutations: next-generation screenings in Caucasian ataxia and spastic paraplegia cohorts , 2014, Orphanet Journal of Rare Diseases.

[18]  J. Schisler,et al.  Ataxia and hypogonadism caused by the loss of ubiquitin ligase activity of the U box protein CHIP. , 2014, Human molecular genetics.

[19]  E. Valente,et al.  Primary cilia in neurodevelopmental disorders , 2014, Nature Reviews Neurology.

[20]  Junnian Zheng,et al.  Diverse roles of C-terminal Hsp70-interacting protein (CHIP) in tumorigenesis , 2014, Journal of Cancer Research and Clinical Oncology.

[21]  Jun Wang,et al.  Identification of CHIP as a Novel Causative Gene for Autosomal Recessive Cerebellar Ataxia , 2013, PloS one.

[22]  John D. Scott,et al.  AKAP signaling complexes: pointing towards the next generation of therapeutic targets? , 2013, Trends in pharmacological sciences.

[23]  N. Mailand,et al.  A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis , 2013, The EMBO journal.

[24]  W. Marshall,et al.  Ciliary Regulation: Disassembly Takes the Spotlight , 2013, Current Biology.

[25]  Susan S. Taylor,et al.  PKA: lessons learned after twenty years. , 2013, Biochimica et biophysica acta.

[26]  G. Baillie,et al.  Reciprocal regulation of PKA and Rac signaling , 2013, Proceedings of the National Academy of Sciences.

[27]  A. Brunetti,et al.  Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth , 2013, Nature Communications.

[28]  P. Verde,et al.  miR-204 Targeting of Ankrd13A Controls Both Mesenchymal Neural Crest and Lens Cell Migration , 2013, PloS one.

[29]  Boyan Zhang,et al.  PCM1 recruits Plk1 to the pericentriolar matrix to promote primary cilia disassembly before mitotic entry , 2013, Journal of Cell Science.

[30]  L. Rangell,et al.  The Ciliary G-Protein-Coupled Receptor Gpr161 Negatively Regulates the Sonic Hedgehog Pathway via cAMP Signaling , 2013, Cell.

[31]  V. Tiranti,et al.  Mutations in COX7B cause microphthalmia with linear skin lesions, an unconventional mitochondrial disease. , 2012, American journal of human genetics.

[32]  R. Bayliss,et al.  Cell cycle regulation by the NEK family of protein kinases , 2012, Journal of Cell Science.

[33]  T. S. Jørgensen,et al.  Primary cilia and aberrant cell signaling in epithelial ovarian cancer , 2012, Cilia.

[34]  S. Michnick,et al.  PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades , 2011, Nature communications.

[35]  V. Stambolic,et al.  Nek family of kinases in cell cycle, checkpoint control and cancer , 2011, Cell Division.

[36]  Surya M. Nauli,et al.  Mechanisms regulating cilia growth and cilia function in endothelial cells , 2011, Cellular and Molecular Life Sciences.

[37]  Juxiang Chen,et al.  Carboxyl terminus of Hsp70‐interacting protein (CHIP) contributes to human glioma oncogenesis , 2011, Cancer science.

[38]  W. Marshall,et al.  Ciliogenesis: building the cell's antenna , 2011, Nature Reviews Molecular Cell Biology.

[39]  T. Jin,et al.  Dual Phosphorylation of Suppressor of Fused (Sufu) by PKA and GSK3β Regulates Its Stability and Localization in the Primary Cilium* , 2011, The Journal of Biological Chemistry.

[40]  N. Tanimoto,et al.  Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye , 2011, Development.

[41]  V. Stambolic,et al.  Nek10 Mediates G2/M Cell Cycle Arrest and MEK Autoactivation in Response to UV Irradiation , 2010, Molecular and Cellular Biology.

[42]  P. Bovolenta,et al.  miR-204 is required for lens and retinal development via Meis2 targeting , 2010, Proceedings of the National Academy of Sciences.

[43]  Leonardo Beccari,et al.  Proper differentiation of photoreceptors and amacrine cells depends on a regulatory loop between NeuroD and Six6 , 2010, Development.

[44]  J. Shah,et al.  Identification of Signaling Pathways Regulating Primary Cilium Length and Flow-Mediated Adaptation , 2010, Current Biology.

[45]  S. Pons,et al.  Sonic-hedgehog-mediated proliferation requires the localization of PKA to the cilium base , 2010, Journal of Cell Science.

[46]  G. V. Prendergast,et al.  Protein Kinase A and B-Raf Mediate Extracellular Signal-Regulated Kinase Activation by Thyrotropin , 2009, Molecular Pharmacology.

[47]  L. Petrucelli,et al.  CHIP regulates leucine-rich repeat kinase-2 ubiquitination, degradation, and toxicity , 2009, Proceedings of the National Academy of Sciences.

[48]  Stephen W. Wilson,et al.  Convergent extension movements and ciliary function are mediated by ofd1, a zebrafish orthologue of the human oral-facial-digital type 1 syndrome gene , 2008, Human molecular genetics.

[49]  E. Golemis,et al.  Primary cilia and the cell cycle. , 2009, Methods in cell biology.

[50]  J. Gleeson,et al.  CEP290 interacts with the centriolar satellite component PCM-1 and is required for Rab8 localization to the primary cilium. , 2008, Human molecular genetics.

[51]  Akira Sawa,et al.  Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses. , 2008, Archives of general psychiatry.

[52]  Andrew J. Murray Pharmacological PKA Inhibition: All May Not Be What It Seems , 2008, Science Signaling.

[53]  J. Eisen,et al.  Controlling morpholino experiments: don't stop making antisense , 2008, Development.

[54]  E. Golemis,et al.  Cell cycle-dependent ciliogenesis and cancer. , 2008, Cancer research.

[55]  G. Dianov,et al.  CHIP-mediated degradation and DNA damage-dependent stabilization regulate base excision repair proteins. , 2008, Molecular cell.

[56]  P. Cohen,et al.  The selectivity of protein kinase inhibitors: a further update. , 2007, The Biochemical journal.

[57]  J. Wittbrodt,et al.  Meganuclease and transposon mediated transgenesis in medaka , 2007, Genome Biology.

[58]  P. Bovolenta,et al.  Comprehensive characterization of the cis-regulatory code responsible for the spatio-temporal expression of olSix3.2 in the developing medaka forebrain , 2007, Genome Biology.

[59]  Susan S. Taylor,et al.  α4 Integrins are Type I cAMP-dependent protein kinase-anchoring proteins , 2007, Nature Cell Biology.

[60]  L. Petrucelli,et al.  Brain CHIP: removing the culprits in neurodegenerative disease. , 2007, Trends in molecular medicine.

[61]  Holly McDonough,et al.  CHIP-mediated stress recovery by sequential ubiquitination of substrates and Hsp70 , 2006, Nature.

[62]  T. Iwamatsu Stages of normal development in the medaka Oryzias latipes , 1994, Mechanisms of Development.

[63]  T. Hashikawa,et al.  CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. , 2002, Molecular cell.

[64]  P. Stork,et al.  PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. , 2002, Molecular cell.

[65]  C. Patterson,et al.  Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling , 2001, Current Biology.

[66]  D. Cyr,et al.  The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation , 2000, Nature Cell Biology.

[67]  R. Idzerda,et al.  Role of Regulatory Subunits and Protein Kinase Inhibitor (PKI) in Determining Nuclear Localization and Activity of the Catalytic Subunit of Protein Kinase A* , 1999, The Journal of Biological Chemistry.

[68]  W. Zimmer,et al.  PCM-1, A 228-kD centrosome autoantigen with a distinct cell cycle distribution , 1994, The Journal of cell biology.