Age and sex differences in muscle sympathetic nerve activity in relation to haemodynamics, blood volume and left ventricular size

What is the central question of this study? The study was designed to investigate the age‐ and sex‐related differences in muscle sympathetic nerve activity (MSNA) in relation to age‐ and sex‐related differences in haemodynamics, blood volume and left ventricular size and function. What is the main finding and its importance? Age‐related increases in MSNA were associated with decreases in blood volume in men only, and only in men was there a significant relation between MSNA and forearm vascular resistance. These results show that age and sex independently alter the neural control of blood pressure and may provide insights into the pathogenesis of hypertension.

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